Limits...
Sudden Death by Pulmonary Thromboembolism due to a Large Uterine Leiomyoma with a Parasitic Vein to the Mesentery.

Podduturi V, Armstrong-Briley DR, Guileyardo JM - Case Rep Obstet Gynecol (2014)

Bottom Line: The pathophysiology of venous thrombosis is classically attributed to alterations in one or more components of Virchow's triad: hypercoagulability, stasis, and damage to the vascular endothelium.Deep vein thrombosis (DVT) may lead to pulmonary thromboembolism (PE), and the latter is culpable for many deaths annually in the United States; however, DVT as a complication of uterine leiomyoma has rarely been reported.We report a case of a 57-year-old woman whose death was due to a large pedunculated subserosal leiomyoma externally compressing the pelvic veins resulting in stasis and venous thrombosis leading to fatal PE.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Baylor University Medical Center, Dallas, TX, USA.

ABSTRACT
The pathophysiology of venous thrombosis is classically attributed to alterations in one or more components of Virchow's triad: hypercoagulability, stasis, and damage to the vascular endothelium. Deep vein thrombosis (DVT) may lead to pulmonary thromboembolism (PE), and the latter is culpable for many deaths annually in the United States; however, DVT as a complication of uterine leiomyoma has rarely been reported. We report a case of a 57-year-old woman whose death was due to a large pedunculated subserosal leiomyoma externally compressing the pelvic veins resulting in stasis and venous thrombosis leading to fatal PE. The association of large pelvic masses with venous thrombosis has clinical implications, since prophylactic surgery could be life-saving.

No MeSH data available.


Related in: MedlinePlus

Ultrasound image showing a large pelvic mass.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4283384&req=5

fig1: Ultrasound image showing a large pelvic mass.

Mentions: Physical examination found diffuse rales, rhonchi, wheezing, and generalized abdominal tenderness. No lower extremity swelling was noted. Her body mass index was 31.8 kg/m2. Chest X-ray showed cardiomegaly and bilateral pulmonary infiltrates suggesting pneumonia. Pelvic sonogram found a large mass suggestive of a fibroid uterus, posterosuperior to the bladder (Figure 1). A nasal swab was positive for H1N1 influenza by PCR. She was placed on empiric antibiotics and BiPAP; however, her respiratory function continued to decline. Thirteen days after admission, she experienced sudden cardiopulmonary arrest and died.


Sudden Death by Pulmonary Thromboembolism due to a Large Uterine Leiomyoma with a Parasitic Vein to the Mesentery.

Podduturi V, Armstrong-Briley DR, Guileyardo JM - Case Rep Obstet Gynecol (2014)

Ultrasound image showing a large pelvic mass.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4283384&req=5

fig1: Ultrasound image showing a large pelvic mass.
Mentions: Physical examination found diffuse rales, rhonchi, wheezing, and generalized abdominal tenderness. No lower extremity swelling was noted. Her body mass index was 31.8 kg/m2. Chest X-ray showed cardiomegaly and bilateral pulmonary infiltrates suggesting pneumonia. Pelvic sonogram found a large mass suggestive of a fibroid uterus, posterosuperior to the bladder (Figure 1). A nasal swab was positive for H1N1 influenza by PCR. She was placed on empiric antibiotics and BiPAP; however, her respiratory function continued to decline. Thirteen days after admission, she experienced sudden cardiopulmonary arrest and died.

Bottom Line: The pathophysiology of venous thrombosis is classically attributed to alterations in one or more components of Virchow's triad: hypercoagulability, stasis, and damage to the vascular endothelium.Deep vein thrombosis (DVT) may lead to pulmonary thromboembolism (PE), and the latter is culpable for many deaths annually in the United States; however, DVT as a complication of uterine leiomyoma has rarely been reported.We report a case of a 57-year-old woman whose death was due to a large pedunculated subserosal leiomyoma externally compressing the pelvic veins resulting in stasis and venous thrombosis leading to fatal PE.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Baylor University Medical Center, Dallas, TX, USA.

ABSTRACT
The pathophysiology of venous thrombosis is classically attributed to alterations in one or more components of Virchow's triad: hypercoagulability, stasis, and damage to the vascular endothelium. Deep vein thrombosis (DVT) may lead to pulmonary thromboembolism (PE), and the latter is culpable for many deaths annually in the United States; however, DVT as a complication of uterine leiomyoma has rarely been reported. We report a case of a 57-year-old woman whose death was due to a large pedunculated subserosal leiomyoma externally compressing the pelvic veins resulting in stasis and venous thrombosis leading to fatal PE. The association of large pelvic masses with venous thrombosis has clinical implications, since prophylactic surgery could be life-saving.

No MeSH data available.


Related in: MedlinePlus