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Ultrasonographic features and clinical implications of benign palpable breast lesions in young women.

Ha R, Kim H, Mango V, Wynn R, Comstock C - Ultrasonography (2014)

Bottom Line: The frequency of benign and malignant descriptor terms that were used to characterize the lesions were compared to the final pathology.Suspicious descriptors were used less frequently by radiologists 1 and 2 including irregular shape (9.2% and 13.1%), non-circumscribed margin (31.6% and 22.4%) and non-parallel orientation (14.5% and 9.2%); the frequency of using all three suspicious descriptors was 9.2% and 11.8%, respectively.Using the BI-RADS lexicon, US accurately predicted benignity in about two thirds of our patients, supporting US surveillance as a safe alternative to invasive tissue sampling in this setting.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Columbia University Medical Center, New York, NY, USA.

ABSTRACT

Purpose: The purpose of this study was to describe the breast ultrasonography (US) features and to investigate whether performing a core biopsy is warranted in young women having palpable solid breast masses.

Methods: A total of 76 solid palpable masses in 68 consecutive women (≤25 years old) underwent tissue diagnosis by percutaneous core biopsy. Two radiologists, who were blinded to the clinical history and histopathology, independently evaluated the US features according to Breast Imaging-Reporting and Data System (BI-RADS) lexicon. The frequency of benign and malignant descriptor terms that were used to characterize the lesions were compared to the final pathology.

Results: All 76 palpable solid masses yielded benign pathology. On the US, the shape of the mass was described by radiologists 1 and 2 as oval or round (63.2% and 71.1%), margin as circumscribed (68.4% and 77.6%) and orientation as parallel (85.5% and 90.8%); the frequency of using all three benign descriptors was 61.8% and 68.5%, respectively. Suspicious descriptors were used less frequently by radiologists 1 and 2 including irregular shape (9.2% and 13.1%), non-circumscribed margin (31.6% and 22.4%) and non-parallel orientation (14.5% and 9.2%); the frequency of using all three suspicious descriptors was 9.2% and 11.8%, respectively.

Conclusion: Despite the variable US features, breast malignancy seems extremely low in 25 years or younger women for palpable breast lesions. Using the BI-RADS lexicon, US accurately predicted benignity in about two thirds of our patients, supporting US surveillance as a safe alternative to invasive tissue sampling in this setting.

No MeSH data available.


Related in: MedlinePlus

A 23-year-old woman with left breast palpable concern.Ultrasonogram shows corresponding mass (between crosshairs) with characteristics described as “oval, circumscribed and parallel” by both radiologists. Biopsy yielded fibroadenoma.
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f1-usg-14043: A 23-year-old woman with left breast palpable concern.Ultrasonogram shows corresponding mass (between crosshairs) with characteristics described as “oval, circumscribed and parallel” by both radiologists. Biopsy yielded fibroadenoma.

Mentions: No malignancy was detected in any of the 76 solid masses found in 68 patients. The 76 benign masses were characterized by two reviewers (blinded regarding pathology) using the updated Stavros criteria (Table 1). On the US, the shape of the mass was described by radiologist 1 as oval or round (63.2%), margin as circumscribed (68.4%) and orientation as parallel (85.5%). By radiologist 2, the shape of the mass was described as oval or round (71.1%), margin as circumscribed (77.6%) and orientation as parallel (90.8%). The frequency of using all three benign descriptors was 61.8% by radiologist 1 and 68.5% by radiologist 2 (Fig. 1). All of these masses corresponded to benign fibroadenomas. Less frequently, suspicious descriptors were used. Suspicious descriptors were used less frequently by radiologist 1 including irregular shape (9.2%), noncircumscribed margin (31.6%), and non-parallel orientation (14.5%) and by radiologist 2 including irregular shape (13.1%), noncircumscribed margin (22.4%), and non-parallel orientation (9.2%). The frequency of using all three suspicious descriptors was 9.2% by radiologist 1 and 11.8% by radiologist 2 (Fig. 2). There showed good agreements for the shape, margin, echogenicity pattern and posterior acoustic features, and excellent agreements for the orientation and lesion boundary between the two readers (Table 2).


Ultrasonographic features and clinical implications of benign palpable breast lesions in young women.

Ha R, Kim H, Mango V, Wynn R, Comstock C - Ultrasonography (2014)

A 23-year-old woman with left breast palpable concern.Ultrasonogram shows corresponding mass (between crosshairs) with characteristics described as “oval, circumscribed and parallel” by both radiologists. Biopsy yielded fibroadenoma.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4282228&req=5

f1-usg-14043: A 23-year-old woman with left breast palpable concern.Ultrasonogram shows corresponding mass (between crosshairs) with characteristics described as “oval, circumscribed and parallel” by both radiologists. Biopsy yielded fibroadenoma.
Mentions: No malignancy was detected in any of the 76 solid masses found in 68 patients. The 76 benign masses were characterized by two reviewers (blinded regarding pathology) using the updated Stavros criteria (Table 1). On the US, the shape of the mass was described by radiologist 1 as oval or round (63.2%), margin as circumscribed (68.4%) and orientation as parallel (85.5%). By radiologist 2, the shape of the mass was described as oval or round (71.1%), margin as circumscribed (77.6%) and orientation as parallel (90.8%). The frequency of using all three benign descriptors was 61.8% by radiologist 1 and 68.5% by radiologist 2 (Fig. 1). All of these masses corresponded to benign fibroadenomas. Less frequently, suspicious descriptors were used. Suspicious descriptors were used less frequently by radiologist 1 including irregular shape (9.2%), noncircumscribed margin (31.6%), and non-parallel orientation (14.5%) and by radiologist 2 including irregular shape (13.1%), noncircumscribed margin (22.4%), and non-parallel orientation (9.2%). The frequency of using all three suspicious descriptors was 9.2% by radiologist 1 and 11.8% by radiologist 2 (Fig. 2). There showed good agreements for the shape, margin, echogenicity pattern and posterior acoustic features, and excellent agreements for the orientation and lesion boundary between the two readers (Table 2).

Bottom Line: The frequency of benign and malignant descriptor terms that were used to characterize the lesions were compared to the final pathology.Suspicious descriptors were used less frequently by radiologists 1 and 2 including irregular shape (9.2% and 13.1%), non-circumscribed margin (31.6% and 22.4%) and non-parallel orientation (14.5% and 9.2%); the frequency of using all three suspicious descriptors was 9.2% and 11.8%, respectively.Using the BI-RADS lexicon, US accurately predicted benignity in about two thirds of our patients, supporting US surveillance as a safe alternative to invasive tissue sampling in this setting.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Columbia University Medical Center, New York, NY, USA.

ABSTRACT

Purpose: The purpose of this study was to describe the breast ultrasonography (US) features and to investigate whether performing a core biopsy is warranted in young women having palpable solid breast masses.

Methods: A total of 76 solid palpable masses in 68 consecutive women (≤25 years old) underwent tissue diagnosis by percutaneous core biopsy. Two radiologists, who were blinded to the clinical history and histopathology, independently evaluated the US features according to Breast Imaging-Reporting and Data System (BI-RADS) lexicon. The frequency of benign and malignant descriptor terms that were used to characterize the lesions were compared to the final pathology.

Results: All 76 palpable solid masses yielded benign pathology. On the US, the shape of the mass was described by radiologists 1 and 2 as oval or round (63.2% and 71.1%), margin as circumscribed (68.4% and 77.6%) and orientation as parallel (85.5% and 90.8%); the frequency of using all three benign descriptors was 61.8% and 68.5%, respectively. Suspicious descriptors were used less frequently by radiologists 1 and 2 including irregular shape (9.2% and 13.1%), non-circumscribed margin (31.6% and 22.4%) and non-parallel orientation (14.5% and 9.2%); the frequency of using all three suspicious descriptors was 9.2% and 11.8%, respectively.

Conclusion: Despite the variable US features, breast malignancy seems extremely low in 25 years or younger women for palpable breast lesions. Using the BI-RADS lexicon, US accurately predicted benignity in about two thirds of our patients, supporting US surveillance as a safe alternative to invasive tissue sampling in this setting.

No MeSH data available.


Related in: MedlinePlus