Limits...
Impaired fear recognition and attentional set-shifting is associated with brain structural changes in alcoholic patients.

Trick L, Kempton MJ, Williams SC, Duka T - Addict Biol (2014)

Bottom Line: We also presented subjects with fearful, disgust and anger facial emotional expressions.Impairments in performance and some of the regional decreases in gray matter were greater in MDTx.Repeated episodes of detoxification from alcohol, related to severity of dependency, are coupled with altered brain structure in areas of emotional regulation, attention and motor planning.

View Article: PubMed Central - PubMed

Affiliation: School of Psychology, University of Sussex, UK.

Show MeSH

Related in: MedlinePlus

Correlations depict the negative relationships between gray matter volumes in inferior frontal gyrus (BA47; raw data) and IED number of trials (a; r = −0.272, P = 0.044) and errors (b; r = −0.291, P = 0.031) of completed stages
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4282104&req=5

fig05: Correlations depict the negative relationships between gray matter volumes in inferior frontal gyrus (BA47; raw data) and IED number of trials (a; r = −0.272, P = 0.044) and errors (b; r = −0.291, P = 0.031) of completed stages

Mentions: There were significant negative correlations between gray matter volume in IFG (BA47) and IED number of trials and errors of completed stages (r = −0.272, P = 0.044 and r = −0.291, P = 0.031, respectively; Fig.  5); and between gray matter volume in posterior insula and IED completed stages number of errors (r = −0.265, P = 0.05). In all cases, these correlations indicate that lower gray matter volumes are associated with impaired IED performance.


Impaired fear recognition and attentional set-shifting is associated with brain structural changes in alcoholic patients.

Trick L, Kempton MJ, Williams SC, Duka T - Addict Biol (2014)

Correlations depict the negative relationships between gray matter volumes in inferior frontal gyrus (BA47; raw data) and IED number of trials (a; r = −0.272, P = 0.044) and errors (b; r = −0.291, P = 0.031) of completed stages
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4282104&req=5

fig05: Correlations depict the negative relationships between gray matter volumes in inferior frontal gyrus (BA47; raw data) and IED number of trials (a; r = −0.272, P = 0.044) and errors (b; r = −0.291, P = 0.031) of completed stages
Mentions: There were significant negative correlations between gray matter volume in IFG (BA47) and IED number of trials and errors of completed stages (r = −0.272, P = 0.044 and r = −0.291, P = 0.031, respectively; Fig.  5); and between gray matter volume in posterior insula and IED completed stages number of errors (r = −0.265, P = 0.05). In all cases, these correlations indicate that lower gray matter volumes are associated with impaired IED performance.

Bottom Line: We also presented subjects with fearful, disgust and anger facial emotional expressions.Impairments in performance and some of the regional decreases in gray matter were greater in MDTx.Repeated episodes of detoxification from alcohol, related to severity of dependency, are coupled with altered brain structure in areas of emotional regulation, attention and motor planning.

View Article: PubMed Central - PubMed

Affiliation: School of Psychology, University of Sussex, UK.

Show MeSH
Related in: MedlinePlus