Impaired fear recognition and attentional set-shifting is associated with brain structural changes in alcoholic patients.
Bottom Line: We also presented subjects with fearful, disgust and anger facial emotional expressions.Impairments in performance and some of the regional decreases in gray matter were greater in MDTx.Repeated episodes of detoxification from alcohol, related to severity of dependency, are coupled with altered brain structure in areas of emotional regulation, attention and motor planning.
Affiliation: School of Psychology, University of Sussex, UK.Show MeSH
Related in: MedlinePlus
Mentions: There were significant negative correlations between gray matter volume in IFG (BA47) and IED number of trials and errors of completed stages (r = −0.272, P = 0.044 and r = −0.291, P = 0.031, respectively; Fig. 5); and between gray matter volume in posterior insula and IED completed stages number of errors (r = −0.265, P = 0.05). In all cases, these correlations indicate that lower gray matter volumes are associated with impaired IED performance.