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Automatic segmentation of anatomical structures from CT scans of thorax for RTP.

Özsavaş EE, Telatar Z, Dirican B, Sağer Ö, Beyzadeoğlu M - Comput Math Methods Med (2014)

Bottom Line: To assess the accuracy, we performed two comparisons between the automatically obtained results and the results obtained manually by an expert.The average volume overlap ratio values range between 94.30 ± 3.93% and 99.11 ± 0.26% on the two different datasets.We obtained the average symmetric surface distance values between the ranges of 0.28 ± 0.21 mm and 0.89 ± 0.32 mm by using the same datasets.

View Article: PubMed Central - PubMed

Affiliation: Electrical and Electronics Engineering Department, Faculty of Engineering, Ankara University, Gölbaşı, 06830 Ankara, Turkey.

ABSTRACT
Modern radiotherapy techniques are vulnerable to delineation inaccuracies owing to the steep dose gradient around the target. In this aspect, accurate contouring comprises an indispensable part of optimal radiation treatment planning (RTP). We suggest a fully automated method to segment the lungs, trachea/main bronchi, and spinal canal accurately from computed tomography (CT) scans of patients with lung cancer to use for RTP. For this purpose, we developed a new algorithm for inclusion of excluded pathological areas into the segmented lungs and a modified version of the fuzzy segmentation by morphological reconstruction for spinal canal segmentation and implemented some image processing algorithms along with them. To assess the accuracy, we performed two comparisons between the automatically obtained results and the results obtained manually by an expert. The average volume overlap ratio values range between 94.30 ± 3.93% and 99.11 ± 0.26% on the two different datasets. We obtained the average symmetric surface distance values between the ranges of 0.28 ± 0.21 mm and 0.89 ± 0.32 mm by using the same datasets. Our method provides favorable results in the segmentation of CT scans of patients with lung cancer and can avoid heavy computational load and might offer expedited segmentation that can be used in RTP.

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Related in: MedlinePlus

Results of three-dimensional region growing for a CT slice: (a) original CT slice, (b) used threshold which is −836 HU, (c) used threshold which is −772 HU, and (d) used threshold which is −708 HU.
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fig4: Results of three-dimensional region growing for a CT slice: (a) original CT slice, (b) used threshold which is −836 HU, (c) used threshold which is −772 HU, and (d) used threshold which is −708 HU.

Mentions: If the segmented structures have a total volume at least twice the structures segmented with the previous threshold, it is considered that the growing region penetrates through the bronchial wall and enters into the lung parenchyma. In this case, value of the increment is reduced by half. This operation is terminated when the increment reaches the value of 1 HU and leakage into the lung field is detected synchronously. Figure 4 shows the segmented trachea/main bronchi areas using different thresholds.


Automatic segmentation of anatomical structures from CT scans of thorax for RTP.

Özsavaş EE, Telatar Z, Dirican B, Sağer Ö, Beyzadeoğlu M - Comput Math Methods Med (2014)

Results of three-dimensional region growing for a CT slice: (a) original CT slice, (b) used threshold which is −836 HU, (c) used threshold which is −772 HU, and (d) used threshold which is −708 HU.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4281476&req=5

fig4: Results of three-dimensional region growing for a CT slice: (a) original CT slice, (b) used threshold which is −836 HU, (c) used threshold which is −772 HU, and (d) used threshold which is −708 HU.
Mentions: If the segmented structures have a total volume at least twice the structures segmented with the previous threshold, it is considered that the growing region penetrates through the bronchial wall and enters into the lung parenchyma. In this case, value of the increment is reduced by half. This operation is terminated when the increment reaches the value of 1 HU and leakage into the lung field is detected synchronously. Figure 4 shows the segmented trachea/main bronchi areas using different thresholds.

Bottom Line: To assess the accuracy, we performed two comparisons between the automatically obtained results and the results obtained manually by an expert.The average volume overlap ratio values range between 94.30 ± 3.93% and 99.11 ± 0.26% on the two different datasets.We obtained the average symmetric surface distance values between the ranges of 0.28 ± 0.21 mm and 0.89 ± 0.32 mm by using the same datasets.

View Article: PubMed Central - PubMed

Affiliation: Electrical and Electronics Engineering Department, Faculty of Engineering, Ankara University, Gölbaşı, 06830 Ankara, Turkey.

ABSTRACT
Modern radiotherapy techniques are vulnerable to delineation inaccuracies owing to the steep dose gradient around the target. In this aspect, accurate contouring comprises an indispensable part of optimal radiation treatment planning (RTP). We suggest a fully automated method to segment the lungs, trachea/main bronchi, and spinal canal accurately from computed tomography (CT) scans of patients with lung cancer to use for RTP. For this purpose, we developed a new algorithm for inclusion of excluded pathological areas into the segmented lungs and a modified version of the fuzzy segmentation by morphological reconstruction for spinal canal segmentation and implemented some image processing algorithms along with them. To assess the accuracy, we performed two comparisons between the automatically obtained results and the results obtained manually by an expert. The average volume overlap ratio values range between 94.30 ± 3.93% and 99.11 ± 0.26% on the two different datasets. We obtained the average symmetric surface distance values between the ranges of 0.28 ± 0.21 mm and 0.89 ± 0.32 mm by using the same datasets. Our method provides favorable results in the segmentation of CT scans of patients with lung cancer and can avoid heavy computational load and might offer expedited segmentation that can be used in RTP.

Show MeSH
Related in: MedlinePlus