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Malignant pediatric gliosarcoma defies general survival data.

Martin J, Devadoss P, Kannan K, Kumar Sundarraj S - Case Rep Med (2014)

Bottom Line: Gliosarcoma, a variant of glioblastoma multiforme, is a dimorphic tumor known for its intra-axial occurrence and poor survival of less than a year.Here is an 11-year-old boy with gliosarcoma.He has lived through the disease for over 34 months with a residual disease.This case report is to report an unusual long survival of gliosarcoma in a teenager (Ravisankar et al., 2012).

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Oncology, Madras Medical College, Chennai, India.

ABSTRACT
Gliosarcoma, a variant of glioblastoma multiforme, is a dimorphic tumor known for its intra-axial occurrence and poor survival of less than a year. Here is an 11-year-old boy with gliosarcoma. He had a near total excision and postoperative chemoradiotherapy. He has lived through the disease for over 34 months with a residual disease.This case report is to report an unusual long survival of gliosarcoma in a teenager (Ravisankar et al., 2012).

No MeSH data available.


Related in: MedlinePlus

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Mentions: Immunostaining for Vimentin showed cytoplasmic positivity in 70% of the cells. Smooth muscle actin showed focal weak positivity in 30% of the cells. Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10–15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9). A final diagnosis of gliosarcoma was then made.


Malignant pediatric gliosarcoma defies general survival data.

Martin J, Devadoss P, Kannan K, Kumar Sundarraj S - Case Rep Med (2014)

S100.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4281457&req=5

fig8: S100.
Mentions: Immunostaining for Vimentin showed cytoplasmic positivity in 70% of the cells. Smooth muscle actin showed focal weak positivity in 30% of the cells. Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10–15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9). A final diagnosis of gliosarcoma was then made.

Bottom Line: Gliosarcoma, a variant of glioblastoma multiforme, is a dimorphic tumor known for its intra-axial occurrence and poor survival of less than a year.Here is an 11-year-old boy with gliosarcoma.He has lived through the disease for over 34 months with a residual disease.This case report is to report an unusual long survival of gliosarcoma in a teenager (Ravisankar et al., 2012).

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Oncology, Madras Medical College, Chennai, India.

ABSTRACT
Gliosarcoma, a variant of glioblastoma multiforme, is a dimorphic tumor known for its intra-axial occurrence and poor survival of less than a year. Here is an 11-year-old boy with gliosarcoma. He had a near total excision and postoperative chemoradiotherapy. He has lived through the disease for over 34 months with a residual disease.This case report is to report an unusual long survival of gliosarcoma in a teenager (Ravisankar et al., 2012).

No MeSH data available.


Related in: MedlinePlus