Limits...
Antimullerian hormone changes after laparoscopic ovarian cystectomy for endometrioma compared with the nonovarian conditions.

Tanprasertkul C, Manusook S, Somprasit C, Ekarattanawong S, Sreshthaputra O, Vutyavanich T - Minim Invasive Surg (2014)

Bottom Line: Objective.However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynaecology, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand ; Center of Excellence in Applied Epidemiology, Thammasat University, Pathum Thani 12120, Thailand.

ABSTRACT
Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects. Objective. To evaluate the impact of laparoscopic ovarian cystectomy for endometrioma on ovarian reserve, measured by serum antimullerian hormone (AMH), compared to nonovarian pelvic surgery. Materials and Methods. A prospective study was conducted. Women who underwent laparoscopic ovarian cystectomy (LOC) and laparoscopic nonovarian pelvic surgery (NOS) were recruited and followed up through 6 months. Clinical baseline data and AMH were evaluated. Results. 39 and 38 participants were enrolled in LOC and NOS groups, respectively. Baseline characteristics (age, weight, BMI, and height) and preoperative AMH level between 2 groups were not statistically different. After surgery, AMH of both groups decreased since the first week, at 1 month and at 3 months. However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference. Conclusion. This study demonstrated the negative impact of nonovarian or indirect effects of laparoscopic surgery to ovarian reserve. The possible mechanisms are necessary for more investigations.

No MeSH data available.


Related in: MedlinePlus

The correlation of serum AMH and age in participants. (AMH: antimullerian hormone).
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4279712&req=5

fig1: The correlation of serum AMH and age in participants. (AMH: antimullerian hormone).

Mentions: As shown in Figure 1, the distribution of serum AMH levels was inversely correlated to the patients' age. After age of 40, the rate of declination was accelerated.


Antimullerian hormone changes after laparoscopic ovarian cystectomy for endometrioma compared with the nonovarian conditions.

Tanprasertkul C, Manusook S, Somprasit C, Ekarattanawong S, Sreshthaputra O, Vutyavanich T - Minim Invasive Surg (2014)

The correlation of serum AMH and age in participants. (AMH: antimullerian hormone).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4279712&req=5

fig1: The correlation of serum AMH and age in participants. (AMH: antimullerian hormone).
Mentions: As shown in Figure 1, the distribution of serum AMH levels was inversely correlated to the patients' age. After age of 40, the rate of declination was accelerated.

Bottom Line: Objective.However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynaecology, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand ; Center of Excellence in Applied Epidemiology, Thammasat University, Pathum Thani 12120, Thailand.

ABSTRACT
Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects. Objective. To evaluate the impact of laparoscopic ovarian cystectomy for endometrioma on ovarian reserve, measured by serum antimullerian hormone (AMH), compared to nonovarian pelvic surgery. Materials and Methods. A prospective study was conducted. Women who underwent laparoscopic ovarian cystectomy (LOC) and laparoscopic nonovarian pelvic surgery (NOS) were recruited and followed up through 6 months. Clinical baseline data and AMH were evaluated. Results. 39 and 38 participants were enrolled in LOC and NOS groups, respectively. Baseline characteristics (age, weight, BMI, and height) and preoperative AMH level between 2 groups were not statistically different. After surgery, AMH of both groups decreased since the first week, at 1 month and at 3 months. However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference. Conclusion. This study demonstrated the negative impact of nonovarian or indirect effects of laparoscopic surgery to ovarian reserve. The possible mechanisms are necessary for more investigations.

No MeSH data available.


Related in: MedlinePlus