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A rare case of splenic marginal zone B-cell lymphoma mimicking relapsing polychondritis of the ear.

Huang GJ, Mendes B, Sheykholeslami K - Case Rep Otolaryngol (2014)

Bottom Line: However, RPC has also been linked to more insidious conditions such as malignancies, autoimmune disorders, vasculitis, or underlying infections.Given the spectrum of associated disorders, patients with RPC may need to be monitored for more insidious underlying conditions.In this case, we report a unique case of bilateral auricular inflammation and nasal inflammation mimicking RPC as the only presenting symptom of splenic marginal zone B-cell lymphoma and we survey related cases in the literature.

View Article: PubMed Central - PubMed

Affiliation: OSF Saint Anthony Health System, Department of Surgery, University of Illinois College of Medicine at Rockford, Rockford, IL 61103, USA.

ABSTRACT
Relapsing polychondritis (RPC) is a poorly understood phenomenon associated with cartilaginous inflammation of the ear, nose, tracheobronchial tree, and peripheral joints. Many cases of RPC respond to anti-inflammatories and resolve with no further complications. However, RPC has also been linked to more insidious conditions such as malignancies, autoimmune disorders, vasculitis, or underlying infections. Given the spectrum of associated disorders, patients with RPC may need to be monitored for more insidious underlying conditions. In this case, we report a unique case of bilateral auricular inflammation and nasal inflammation mimicking RPC as the only presenting symptom of splenic marginal zone B-cell lymphoma and we survey related cases in the literature.

No MeSH data available.


Related in: MedlinePlus

Left lateral view, initial visit.
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Related In: Results  -  Collection


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fig1: Left lateral view, initial visit.

Mentions: Patient was referred to otolaryngology for evaluation. Physical examination was significant for erythematous, edematous, tender auricles bilaterally (Figures 1 and 2), and nasal tip with unremarkable findings on the rest of the exam. The left auricle had the classic lobule-sparing inflammation of RPC, whereas the right auricle presented with tenderness of the entire ear. A punch biopsy was performed due to clinical suspicion for relapsing polychondritis.


A rare case of splenic marginal zone B-cell lymphoma mimicking relapsing polychondritis of the ear.

Huang GJ, Mendes B, Sheykholeslami K - Case Rep Otolaryngol (2014)

Left lateral view, initial visit.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4269282&req=5

fig1: Left lateral view, initial visit.
Mentions: Patient was referred to otolaryngology for evaluation. Physical examination was significant for erythematous, edematous, tender auricles bilaterally (Figures 1 and 2), and nasal tip with unremarkable findings on the rest of the exam. The left auricle had the classic lobule-sparing inflammation of RPC, whereas the right auricle presented with tenderness of the entire ear. A punch biopsy was performed due to clinical suspicion for relapsing polychondritis.

Bottom Line: However, RPC has also been linked to more insidious conditions such as malignancies, autoimmune disorders, vasculitis, or underlying infections.Given the spectrum of associated disorders, patients with RPC may need to be monitored for more insidious underlying conditions.In this case, we report a unique case of bilateral auricular inflammation and nasal inflammation mimicking RPC as the only presenting symptom of splenic marginal zone B-cell lymphoma and we survey related cases in the literature.

View Article: PubMed Central - PubMed

Affiliation: OSF Saint Anthony Health System, Department of Surgery, University of Illinois College of Medicine at Rockford, Rockford, IL 61103, USA.

ABSTRACT
Relapsing polychondritis (RPC) is a poorly understood phenomenon associated with cartilaginous inflammation of the ear, nose, tracheobronchial tree, and peripheral joints. Many cases of RPC respond to anti-inflammatories and resolve with no further complications. However, RPC has also been linked to more insidious conditions such as malignancies, autoimmune disorders, vasculitis, or underlying infections. Given the spectrum of associated disorders, patients with RPC may need to be monitored for more insidious underlying conditions. In this case, we report a unique case of bilateral auricular inflammation and nasal inflammation mimicking RPC as the only presenting symptom of splenic marginal zone B-cell lymphoma and we survey related cases in the literature.

No MeSH data available.


Related in: MedlinePlus