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Glycolipids from seaweeds and their potential biotechnological applications.

Plouguerné E, da Gama BA, Pereira RC, Barreto-Bergter E - Front Cell Infect Microbiol (2014)

Bottom Line: The great majority of the published works have focused on terpenoids.In comparison, glycolipids are a neglected class of macroalgal secondary metabolites therefore remaining as a largely unknown reservoir of molecular diversity.Nevertheless, the interest regarding these compounds has been growing fast in the last decades as activities of ecological or pharmaceutical interest have been highlighted.

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Affiliation: Laboratório de Produtos Naturais e Ecologia Química Marinha, Departamento de Biologia Marinha, Instituto de Biologia, Universidade Federal Fluminense Niterói, Brazil.

ABSTRACT
Marine macroalgae, or seaweeds, are a formidable source of natural compounds with diverse biological activities. In the last five decades it has been estimated that more than 3000 natural compounds were discovered from these organisms. The great majority of the published works have focused on terpenoids. In comparison, glycolipids are a neglected class of macroalgal secondary metabolites therefore remaining as a largely unknown reservoir of molecular diversity. Nevertheless, the interest regarding these compounds has been growing fast in the last decades as activities of ecological or pharmaceutical interest have been highlighted. This paper will review recent work regarding isolation and structural characterization of glycolipids from seaweeds and their prospective biological activities.

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General structure of the three main glycoglycerolipids from seaweeds. R, acyl chain.
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Figure 1: General structure of the three main glycoglycerolipids from seaweeds. R, acyl chain.

Mentions: With an estimation of more than 30,000 species identified around the world, marine macroalgae, or seaweeds, constitute a huge source of natural compounds with diverse biological activities (Guiry, 2012). In the last 50 years it has been estimated that more than 3000 natural compounds were discovered from these organisms (Leal et al., 2013). The great majority of the published works have focused on terpenoids, phenolic compounds, or polysaccharides. Glycolipids represent a less studied class of metabolites with recently growing interest. Seaweeds biosynthesize three major types of glycolipids: monogalactosyldiacylglycerides (MGDGs), digalactosyldiacylglycerides (DGDGs), and sulfoquinovosyldiacylglycerides (SQDGs) (Figure 1).


Glycolipids from seaweeds and their potential biotechnological applications.

Plouguerné E, da Gama BA, Pereira RC, Barreto-Bergter E - Front Cell Infect Microbiol (2014)

General structure of the three main glycoglycerolipids from seaweeds. R, acyl chain.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4269193&req=5

Figure 1: General structure of the three main glycoglycerolipids from seaweeds. R, acyl chain.
Mentions: With an estimation of more than 30,000 species identified around the world, marine macroalgae, or seaweeds, constitute a huge source of natural compounds with diverse biological activities (Guiry, 2012). In the last 50 years it has been estimated that more than 3000 natural compounds were discovered from these organisms (Leal et al., 2013). The great majority of the published works have focused on terpenoids, phenolic compounds, or polysaccharides. Glycolipids represent a less studied class of metabolites with recently growing interest. Seaweeds biosynthesize three major types of glycolipids: monogalactosyldiacylglycerides (MGDGs), digalactosyldiacylglycerides (DGDGs), and sulfoquinovosyldiacylglycerides (SQDGs) (Figure 1).

Bottom Line: The great majority of the published works have focused on terpenoids.In comparison, glycolipids are a neglected class of macroalgal secondary metabolites therefore remaining as a largely unknown reservoir of molecular diversity.Nevertheless, the interest regarding these compounds has been growing fast in the last decades as activities of ecological or pharmaceutical interest have been highlighted.

View Article: PubMed Central - PubMed

Affiliation: Laboratório de Produtos Naturais e Ecologia Química Marinha, Departamento de Biologia Marinha, Instituto de Biologia, Universidade Federal Fluminense Niterói, Brazil.

ABSTRACT
Marine macroalgae, or seaweeds, are a formidable source of natural compounds with diverse biological activities. In the last five decades it has been estimated that more than 3000 natural compounds were discovered from these organisms. The great majority of the published works have focused on terpenoids. In comparison, glycolipids are a neglected class of macroalgal secondary metabolites therefore remaining as a largely unknown reservoir of molecular diversity. Nevertheless, the interest regarding these compounds has been growing fast in the last decades as activities of ecological or pharmaceutical interest have been highlighted. This paper will review recent work regarding isolation and structural characterization of glycolipids from seaweeds and their prospective biological activities.

Show MeSH