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Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence.

Goodman M, Mandel JS, DeSesso JM, Scialli AR - Birth Defects Res. B Dev. Reprod. Toxicol. (2014)

Bottom Line: As a quantitative meta-analysis was not feasible, the study results were categorized qualitatively as positive, , or mixed.Without good quality data, the results are difficult to assess; however, it is worth noting that none of the outcome categories demonstrated consistent positive associations across studies.Considering the poor quality of the data and the lack of robust findings across studies, conclusions about a causal link between ATR and adverse pregnancy outcomes are not warranted.

View Article: PubMed Central - PubMed

Affiliation: Emory University School of Public Health, Atlanta, Georgia.

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Related in: MedlinePlus

Overview of study findings on the associations between ATR/triazine herbicide (or surrogate) and pregnancy outcomes other than birth defects.
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Related In: Results  -  Collection


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fig02: Overview of study findings on the associations between ATR/triazine herbicide (or surrogate) and pregnancy outcomes other than birth defects.

Mentions: As shown in Figure 2, the most commonly addressed endpoints in this group of studies were SGA (six reports) and premature delivery (four reports). As with data for birth defects, none of the outcome categories demonstrated consistent positive associations across studies. For most outcomes, a weight of evidence assessment was not possible because they were examined in only one or two studies.


Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence.

Goodman M, Mandel JS, DeSesso JM, Scialli AR - Birth Defects Res. B Dev. Reprod. Toxicol. (2014)

Overview of study findings on the associations between ATR/triazine herbicide (or surrogate) and pregnancy outcomes other than birth defects.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4265844&req=5

fig02: Overview of study findings on the associations between ATR/triazine herbicide (or surrogate) and pregnancy outcomes other than birth defects.
Mentions: As shown in Figure 2, the most commonly addressed endpoints in this group of studies were SGA (six reports) and premature delivery (four reports). As with data for birth defects, none of the outcome categories demonstrated consistent positive associations across studies. For most outcomes, a weight of evidence assessment was not possible because they were examined in only one or two studies.

Bottom Line: As a quantitative meta-analysis was not feasible, the study results were categorized qualitatively as positive, , or mixed.Without good quality data, the results are difficult to assess; however, it is worth noting that none of the outcome categories demonstrated consistent positive associations across studies.Considering the poor quality of the data and the lack of robust findings across studies, conclusions about a causal link between ATR and adverse pregnancy outcomes are not warranted.

View Article: PubMed Central - PubMed

Affiliation: Emory University School of Public Health, Atlanta, Georgia.

Show MeSH
Related in: MedlinePlus