Limits...
Radiofrequency-treated recurrence of urothelial carcinoma of the upper urinary tract after nephroureterectomy.

Molina R, Alvarez M, Capilla J, Páez A - Korean J Urol (2014)

Bottom Line: The usual treatment is systemic chemotherapy followed by optional resection of the mass.The patient was treated with computed tomography-guided percutaneous radiofrequency ablation.Twenty-four months after the procedure, the patient is free of the disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Fuenlabrada Universitary Hospital, Madrid, Spain.

ABSTRACT
Local recurrence after radical nephroureterectomy (RNU) owing to urothelial carcinoma of the upper urinary tract is rare. The usual treatment is systemic chemotherapy followed by optional resection of the mass. We introduce the case of a 73-year-old male patient with multiple comorbidities in whom retroperitoneal carcinoma recurrence of 31 mm was diagnosed via positron emission tomography-computed tomography scan with 18-fluorodeoxyglucose about 5 years after he had undergone RNU owing to urothelial carcinoma of the upper urinary tract. The patient was treated with computed tomography-guided percutaneous radiofrequency ablation. Later scans with contrast controls showed lack of contrast uptake and a decrease of the lesion's size. Twenty-four months after the procedure, the patient is free of the disease. To date, this is the first case of recurrence of urothelial carcinoma that was treated with percutaneous radiofrequency ablation, thus establishing an alternative to chemotherapy in patients with substantial comorbidities.

Show MeSH

Related in: MedlinePlus

Computed tomography scan showing a 31-mm lesion with contrast uptake contiguous to the medial border of the right hepatic lobe (white arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4265721&req=5

Figure 1: Computed tomography scan showing a 31-mm lesion with contrast uptake contiguous to the medial border of the right hepatic lobe (white arrow).

Mentions: Three years later, during a follow-up CT scan, the patient showed a 31-mm long lesion with contrast uptake in his right renal bed contiguous to the medial border of the right hepatic lobe (Fig. 1). A positron emission tomography (PET)-CT scan with 18-fluorodeoxyglucose was performed, revealing metabolic activity in the surgical bed. After this discovery, a percutaneous biopsy was performed. The anatomopathological diagnosis was high-grade urothelial carcinoma, and the patient was diagnosed with retroperitoneal recurrence of urothelial carcinoma (Fig. 2).


Radiofrequency-treated recurrence of urothelial carcinoma of the upper urinary tract after nephroureterectomy.

Molina R, Alvarez M, Capilla J, Páez A - Korean J Urol (2014)

Computed tomography scan showing a 31-mm lesion with contrast uptake contiguous to the medial border of the right hepatic lobe (white arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4265721&req=5

Figure 1: Computed tomography scan showing a 31-mm lesion with contrast uptake contiguous to the medial border of the right hepatic lobe (white arrow).
Mentions: Three years later, during a follow-up CT scan, the patient showed a 31-mm long lesion with contrast uptake in his right renal bed contiguous to the medial border of the right hepatic lobe (Fig. 1). A positron emission tomography (PET)-CT scan with 18-fluorodeoxyglucose was performed, revealing metabolic activity in the surgical bed. After this discovery, a percutaneous biopsy was performed. The anatomopathological diagnosis was high-grade urothelial carcinoma, and the patient was diagnosed with retroperitoneal recurrence of urothelial carcinoma (Fig. 2).

Bottom Line: The usual treatment is systemic chemotherapy followed by optional resection of the mass.The patient was treated with computed tomography-guided percutaneous radiofrequency ablation.Twenty-four months after the procedure, the patient is free of the disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Fuenlabrada Universitary Hospital, Madrid, Spain.

ABSTRACT
Local recurrence after radical nephroureterectomy (RNU) owing to urothelial carcinoma of the upper urinary tract is rare. The usual treatment is systemic chemotherapy followed by optional resection of the mass. We introduce the case of a 73-year-old male patient with multiple comorbidities in whom retroperitoneal carcinoma recurrence of 31 mm was diagnosed via positron emission tomography-computed tomography scan with 18-fluorodeoxyglucose about 5 years after he had undergone RNU owing to urothelial carcinoma of the upper urinary tract. The patient was treated with computed tomography-guided percutaneous radiofrequency ablation. Later scans with contrast controls showed lack of contrast uptake and a decrease of the lesion's size. Twenty-four months after the procedure, the patient is free of the disease. To date, this is the first case of recurrence of urothelial carcinoma that was treated with percutaneous radiofrequency ablation, thus establishing an alternative to chemotherapy in patients with substantial comorbidities.

Show MeSH
Related in: MedlinePlus