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Prediction of extrathyroidal extension using ultrasonography and computed tomography.

Lee DY, Kwon TK, Sung MW, Kim KH, Hah JH - Int J Endocrinol (2014)

Bottom Line: Methods.Results.Conclusions.

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of Korea.

ABSTRACT
Objectives. The aim of the present study was to evaluate the value of high-resolution ultrasound (US) and computed tomography (CT) scan for preoperative prediction of the extrathyroidal extension (ETE). Methods. We analyzed the medical records of 377 patients with papillary thyroid carcinoma (PTC) with preoperative US and CT scan to calculate the sensitivity, specificity, and positive and negative predictive values of characteristics imaging features (such as contact and disruption of thyroid capsule) for the presence of ETE in postoperative pathologic examination. We also evaluated the diagnostic power for several combinations of US and CT findings. Results. ETE was present in 174 (46.2%) based on pathologic reports. The frequency of ETE was greater in the patients with greater degrees of tumor contact and disruption of capsule, as revealed by both US and CT scans (positive predictive value of 72.2% and 81.8%, resp.). Considering positive predictive values and AUC of US and CT categories, separately or combined, a combination of US and CT findings was most accurate for predicting ETE (83.0%, 0.744). Conclusions. This study suggests that ETE can be predicted most accurately by a combination of categories based on the findings of US and CT scans.

No MeSH data available.


Related in: MedlinePlus

Grouping of thyroid tumor according to ultrasonographic findings. (a) Group 1: the tumor is completely enveloped by thyroid parenchyma, (b) Group 2: the tumor is attached to the thyroid capsule without definite destruction of the capsule, (c) Group 3: the tumor destroys the thyroid capsule and the capsule shadow is disconnected.
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fig1: Grouping of thyroid tumor according to ultrasonographic findings. (a) Group 1: the tumor is completely enveloped by thyroid parenchyma, (b) Group 2: the tumor is attached to the thyroid capsule without definite destruction of the capsule, (c) Group 3: the tumor destroys the thyroid capsule and the capsule shadow is disconnected.

Mentions: Parameters investigated were patient's age, gender, surgical procedure performed, preoperative US and CT findings, and pathologic reports. For US, the thyroid nodule was evaluated by the standard methodology from published reports, including size, composition, echogenicity of the solid tissue, orientation, shape, margin, and calcification [4, 7–11]. We categorize the US tumor characteristics in three groups: Group 1, a tumor which was completely enveloped by thyroid parenchyma; Group 2, a tumor which was attached to the thyroid capsule without definite destruction of the capsule; and Group 3, a tumor attached to the thyroid capsule with loss of capsule shadow (Figure 1).


Prediction of extrathyroidal extension using ultrasonography and computed tomography.

Lee DY, Kwon TK, Sung MW, Kim KH, Hah JH - Int J Endocrinol (2014)

Grouping of thyroid tumor according to ultrasonographic findings. (a) Group 1: the tumor is completely enveloped by thyroid parenchyma, (b) Group 2: the tumor is attached to the thyroid capsule without definite destruction of the capsule, (c) Group 3: the tumor destroys the thyroid capsule and the capsule shadow is disconnected.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4265702&req=5

fig1: Grouping of thyroid tumor according to ultrasonographic findings. (a) Group 1: the tumor is completely enveloped by thyroid parenchyma, (b) Group 2: the tumor is attached to the thyroid capsule without definite destruction of the capsule, (c) Group 3: the tumor destroys the thyroid capsule and the capsule shadow is disconnected.
Mentions: Parameters investigated were patient's age, gender, surgical procedure performed, preoperative US and CT findings, and pathologic reports. For US, the thyroid nodule was evaluated by the standard methodology from published reports, including size, composition, echogenicity of the solid tissue, orientation, shape, margin, and calcification [4, 7–11]. We categorize the US tumor characteristics in three groups: Group 1, a tumor which was completely enveloped by thyroid parenchyma; Group 2, a tumor which was attached to the thyroid capsule without definite destruction of the capsule; and Group 3, a tumor attached to the thyroid capsule with loss of capsule shadow (Figure 1).

Bottom Line: Methods.Results.Conclusions.

View Article: PubMed Central - PubMed

Affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of Korea.

ABSTRACT
Objectives. The aim of the present study was to evaluate the value of high-resolution ultrasound (US) and computed tomography (CT) scan for preoperative prediction of the extrathyroidal extension (ETE). Methods. We analyzed the medical records of 377 patients with papillary thyroid carcinoma (PTC) with preoperative US and CT scan to calculate the sensitivity, specificity, and positive and negative predictive values of characteristics imaging features (such as contact and disruption of thyroid capsule) for the presence of ETE in postoperative pathologic examination. We also evaluated the diagnostic power for several combinations of US and CT findings. Results. ETE was present in 174 (46.2%) based on pathologic reports. The frequency of ETE was greater in the patients with greater degrees of tumor contact and disruption of capsule, as revealed by both US and CT scans (positive predictive value of 72.2% and 81.8%, resp.). Considering positive predictive values and AUC of US and CT categories, separately or combined, a combination of US and CT findings was most accurate for predicting ETE (83.0%, 0.744). Conclusions. This study suggests that ETE can be predicted most accurately by a combination of categories based on the findings of US and CT scans.

No MeSH data available.


Related in: MedlinePlus