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Tea and coffee consumption and risk of laryngeal cancer: a systematic review meta-analysis.

Chen J, Long S - PLoS ONE (2014)

Bottom Line: A meta-analysis was obtained to combine study-specific RRs with a random-effects model.The overall analysis of all 10 studies, including the case-control and cohort studies, found that tea drinking was not associated with laryngeal carcinoma (RR = 1.03; 95% CI: 0.66-1.61).However, coffee consumption was significantly associated with the laryngeal carcinoma (RR = 1.47; 95% CI: 1.03-2.11).

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Central South University Affiliated The Third Xiangya Hospital, Changsha, Hunan, China.

ABSTRACT

Background: Tea and coffee are the most commonly consumed beverages in the worldwide. The relationship between tea and coffee consumption on the risk of laryngeal cancer was still unclear.

Methods: Relevant studies were identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013. Observational studies that reported RRs and 95% CIs for the link of tea and coffee consumption on the risk of laryngeal cancer were eligible. A meta-analysis was obtained to combine study-specific RRs with a random-effects model.

Results: A total of 2,803 cases and 503,234 controls in 10 independent studies were identified. The overall analysis of all 10 studies, including the case-control and cohort studies, found that tea drinking was not associated with laryngeal carcinoma (RR = 1.03; 95% CI: 0.66-1.61). However, coffee consumption was significantly associated with the laryngeal carcinoma (RR = 1.47; 95% CI: 1.03-2.11). A dose-response relationship between coffee intake and laryngeal carcinoma was detected; however, no evidence of dose-response link between tea consumption and laryngeal carcinoma risk was detected.

Conclusions: The results from this meta-analysis of observational studies demonstrate that coffee consumption would increase the laryngeal cancer risk, while tea intake was not associated with risk of laryngeal carcinoma.

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Related in: MedlinePlus

Funnel plot of all the included studies.Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (A). Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (B).
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pone-0112006-g004: Funnel plot of all the included studies.Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (A). Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (B).

Mentions: The funnel plot for both tea intake (Fig. 4A) and coffee intake (Fig. 4B) and risk of laryngeal carcinoma. No indication of publication bias was observed in the literature on tea (Egger's test, P = 0.352) and coffee consumption (Egger's test, P = 0.446) and risk of laryngeal carcinoma.


Tea and coffee consumption and risk of laryngeal cancer: a systematic review meta-analysis.

Chen J, Long S - PLoS ONE (2014)

Funnel plot of all the included studies.Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (A). Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (B).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4264690&req=5

pone-0112006-g004: Funnel plot of all the included studies.Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (A). Funnel plot of the RR vs the standard error of the log RR for studies evaluating tea consumption and laryngeal cancer (B).
Mentions: The funnel plot for both tea intake (Fig. 4A) and coffee intake (Fig. 4B) and risk of laryngeal carcinoma. No indication of publication bias was observed in the literature on tea (Egger's test, P = 0.352) and coffee consumption (Egger's test, P = 0.446) and risk of laryngeal carcinoma.

Bottom Line: A meta-analysis was obtained to combine study-specific RRs with a random-effects model.The overall analysis of all 10 studies, including the case-control and cohort studies, found that tea drinking was not associated with laryngeal carcinoma (RR = 1.03; 95% CI: 0.66-1.61).However, coffee consumption was significantly associated with the laryngeal carcinoma (RR = 1.47; 95% CI: 1.03-2.11).

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Central South University Affiliated The Third Xiangya Hospital, Changsha, Hunan, China.

ABSTRACT

Background: Tea and coffee are the most commonly consumed beverages in the worldwide. The relationship between tea and coffee consumption on the risk of laryngeal cancer was still unclear.

Methods: Relevant studies were identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013. Observational studies that reported RRs and 95% CIs for the link of tea and coffee consumption on the risk of laryngeal cancer were eligible. A meta-analysis was obtained to combine study-specific RRs with a random-effects model.

Results: A total of 2,803 cases and 503,234 controls in 10 independent studies were identified. The overall analysis of all 10 studies, including the case-control and cohort studies, found that tea drinking was not associated with laryngeal carcinoma (RR = 1.03; 95% CI: 0.66-1.61). However, coffee consumption was significantly associated with the laryngeal carcinoma (RR = 1.47; 95% CI: 1.03-2.11). A dose-response relationship between coffee intake and laryngeal carcinoma was detected; however, no evidence of dose-response link between tea consumption and laryngeal carcinoma risk was detected.

Conclusions: The results from this meta-analysis of observational studies demonstrate that coffee consumption would increase the laryngeal cancer risk, while tea intake was not associated with risk of laryngeal carcinoma.

Show MeSH
Related in: MedlinePlus