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Are There Any Connections between Language Deficits and Cognitive Slowing in Alzheimer's Disease?

Schecker M, Kochler C, Schmidtke K, Rauh R - Dement Geriatr Cogn Dis Extra (2014)

Bottom Line: The AD patients showed significantly worse results in all language tests as well as much longer reaction times in all Stroop conditions, especially in the interference condition (Stroop 3).Speech errors and response times correlated with severity (MMSE), and the speech errors correlated with the reaction times in Stroop 3 (interference condition, which reflects the processing time of executive processes).The most interesting question now is: How are language processing and executive processing time (Stroop 3) related?

View Article: PubMed Central - PubMed

Affiliation: Neurolinguistisches Labor NLL, Klinik für Psychiatrie, Psychotherapie und Psychosomatik im Kindes- und Jugendalter, Universität Freiburg, Freiburg, Germany.

ABSTRACT

Background: Speech disorders already occur in the early phases of Alzheimer's disease (AD). As a possible cause, problems of executive processes are discussed. Cognitive slowing is also repeatedly addressed.

Aims: Are there any connections between cognitive slowing and speech disorders in AD? And is there a relationship between cognitive slowing and executive processes?

Methods: The data of 72 healthy controls and 52 AD patients were examined with regard to their language performance and their response times in a computerized Stroop paradigm.

Results: The AD patients showed significantly worse results in all language tests as well as much longer reaction times in all Stroop conditions, especially in the interference condition (Stroop 3). Speech errors and response times correlated with severity (MMSE), and the speech errors correlated with the reaction times in Stroop 3 (interference condition, which reflects the processing time of executive processes).

Conclusion: The most interesting question now is: How are language processing and executive processing time (Stroop 3) related?

No MeSH data available.


Related in: MedlinePlus

Comprehension of idioms.
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Related In: Results  -  Collection

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Figure 2: Comprehension of idioms.

Mentions: Second, we tested the ability to represent context and to integrate contextual cues in information processing using the PMA® (Predictive Monitoring in AD, a test package that we developed at the Neurolinguistic Laboratory Freiburg [10]). Here we used the 3 subtests shown in figures 1, 2, 3 (number of test items per test = 10, no time limit). The statement in subtest 1 (fig. 1) always refers to the lower-frequency meaning of the homonym. The pictures were distributed in random order.


Are There Any Connections between Language Deficits and Cognitive Slowing in Alzheimer's Disease?

Schecker M, Kochler C, Schmidtke K, Rauh R - Dement Geriatr Cogn Dis Extra (2014)

Comprehension of idioms.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4264518&req=5

Figure 2: Comprehension of idioms.
Mentions: Second, we tested the ability to represent context and to integrate contextual cues in information processing using the PMA® (Predictive Monitoring in AD, a test package that we developed at the Neurolinguistic Laboratory Freiburg [10]). Here we used the 3 subtests shown in figures 1, 2, 3 (number of test items per test = 10, no time limit). The statement in subtest 1 (fig. 1) always refers to the lower-frequency meaning of the homonym. The pictures were distributed in random order.

Bottom Line: The AD patients showed significantly worse results in all language tests as well as much longer reaction times in all Stroop conditions, especially in the interference condition (Stroop 3).Speech errors and response times correlated with severity (MMSE), and the speech errors correlated with the reaction times in Stroop 3 (interference condition, which reflects the processing time of executive processes).The most interesting question now is: How are language processing and executive processing time (Stroop 3) related?

View Article: PubMed Central - PubMed

Affiliation: Neurolinguistisches Labor NLL, Klinik für Psychiatrie, Psychotherapie und Psychosomatik im Kindes- und Jugendalter, Universität Freiburg, Freiburg, Germany.

ABSTRACT

Background: Speech disorders already occur in the early phases of Alzheimer's disease (AD). As a possible cause, problems of executive processes are discussed. Cognitive slowing is also repeatedly addressed.

Aims: Are there any connections between cognitive slowing and speech disorders in AD? And is there a relationship between cognitive slowing and executive processes?

Methods: The data of 72 healthy controls and 52 AD patients were examined with regard to their language performance and their response times in a computerized Stroop paradigm.

Results: The AD patients showed significantly worse results in all language tests as well as much longer reaction times in all Stroop conditions, especially in the interference condition (Stroop 3). Speech errors and response times correlated with severity (MMSE), and the speech errors correlated with the reaction times in Stroop 3 (interference condition, which reflects the processing time of executive processes).

Conclusion: The most interesting question now is: How are language processing and executive processing time (Stroop 3) related?

No MeSH data available.


Related in: MedlinePlus