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The effect of 3-thiopheneacetic Acid in the polymerization of a conductive electrotextile for use in biosensor development.

McGraw SK, Alocilja E, Senecal A, Senecal K - Biosensors (Basel) (2013)

Bottom Line: The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites.It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements.A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

View Article: PubMed Central - PubMed

Affiliation: Biosystems and Agricultural Engineering, Michigan State University, 524 S. Shaw Lane, 115 Farrall Hall, East Lansing, MI 48824, USA. shannon.k.mcgraw2.civ@mail.mil.

ABSTRACT
Investigations were conducted to develop an electrotextile using a nonwoven polypropylene fiber platform conformally coated in a conductive, functionalized copolymer of polypyrrole and 3-thiopheneacetic acid (3TAA). The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites. It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements. These factors were used to determine which of the tested concentrations was best for biosensor development. A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

No MeSH data available.


Change in sulfur weight percent at 100× magnification using energy dispersive spectroscopy (EDS) based on increasing 3TAA concentrations. The overall trend shows the sulfur weight percentage increasing as the concentration of 3TAA increases in the sample, starting at 1 mg/mL.
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biosensors-03-00286-f003: Change in sulfur weight percent at 100× magnification using energy dispersive spectroscopy (EDS) based on increasing 3TAA concentrations. The overall trend shows the sulfur weight percentage increasing as the concentration of 3TAA increases in the sample, starting at 1 mg/mL.

Mentions: The sulfur weight percent measured in each sample can be seen in Table 1, ranging from 0.55% to 3.83%. All of the samples with 3TAA concentrations of 10 mg/mL or higher have a sulfur weight percent of greater than 1%. The measured sulfur weight percent decreases by 0.38% between 0 and 1 mg/mL. The range between the measurements of the samples containing 10 and 20 mg/mL of 3TAA is 0.24%. A sharp increase in the weight percent of sulfur is observed between the samples containing 50 and 100 mg/mL of 3TAA with a range of 1.59%. Because sulfur is also present in the dopant, 5SSA, only changes in the sulfur weight percent from the sample containing 0 mg/mL 3TAA can be attributed to the 3TAA presence. The relationship between the weight percent of sulfur and the concentration of 3TAA in each sample can be seen in Figure 3.


The effect of 3-thiopheneacetic Acid in the polymerization of a conductive electrotextile for use in biosensor development.

McGraw SK, Alocilja E, Senecal A, Senecal K - Biosensors (Basel) (2013)

Change in sulfur weight percent at 100× magnification using energy dispersive spectroscopy (EDS) based on increasing 3TAA concentrations. The overall trend shows the sulfur weight percentage increasing as the concentration of 3TAA increases in the sample, starting at 1 mg/mL.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4263581&req=5

biosensors-03-00286-f003: Change in sulfur weight percent at 100× magnification using energy dispersive spectroscopy (EDS) based on increasing 3TAA concentrations. The overall trend shows the sulfur weight percentage increasing as the concentration of 3TAA increases in the sample, starting at 1 mg/mL.
Mentions: The sulfur weight percent measured in each sample can be seen in Table 1, ranging from 0.55% to 3.83%. All of the samples with 3TAA concentrations of 10 mg/mL or higher have a sulfur weight percent of greater than 1%. The measured sulfur weight percent decreases by 0.38% between 0 and 1 mg/mL. The range between the measurements of the samples containing 10 and 20 mg/mL of 3TAA is 0.24%. A sharp increase in the weight percent of sulfur is observed between the samples containing 50 and 100 mg/mL of 3TAA with a range of 1.59%. Because sulfur is also present in the dopant, 5SSA, only changes in the sulfur weight percent from the sample containing 0 mg/mL 3TAA can be attributed to the 3TAA presence. The relationship between the weight percent of sulfur and the concentration of 3TAA in each sample can be seen in Figure 3.

Bottom Line: The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites.It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements.A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

View Article: PubMed Central - PubMed

Affiliation: Biosystems and Agricultural Engineering, Michigan State University, 524 S. Shaw Lane, 115 Farrall Hall, East Lansing, MI 48824, USA. shannon.k.mcgraw2.civ@mail.mil.

ABSTRACT
Investigations were conducted to develop an electrotextile using a nonwoven polypropylene fiber platform conformally coated in a conductive, functionalized copolymer of polypyrrole and 3-thiopheneacetic acid (3TAA). The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites. It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements. These factors were used to determine which of the tested concentrations was best for biosensor development. A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

No MeSH data available.