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The effect of 3-thiopheneacetic Acid in the polymerization of a conductive electrotextile for use in biosensor development.

McGraw SK, Alocilja E, Senecal A, Senecal K - Biosensors (Basel) (2013)

Bottom Line: The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites.It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements.A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

View Article: PubMed Central - PubMed

Affiliation: Biosystems and Agricultural Engineering, Michigan State University, 524 S. Shaw Lane, 115 Farrall Hall, East Lansing, MI 48824, USA. shannon.k.mcgraw2.civ@mail.mil.

ABSTRACT
Investigations were conducted to develop an electrotextile using a nonwoven polypropylene fiber platform conformally coated in a conductive, functionalized copolymer of polypyrrole and 3-thiopheneacetic acid (3TAA). The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites. It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements. These factors were used to determine which of the tested concentrations was best for biosensor development. A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

No MeSH data available.


SEM images of fibers with polymer coating at 5,000× magnification. (A) 3TAA concentration of 10 mg/mL. A smooth conformal polymer coating was observed along the individual fibers with minimal polymer clusters. (B) 3TAA concentration of 100 mg/mL. The coating is rough, with a large amount of polymer built up along the surface, engulfing several fibers and reducing the porosity of the membrane.
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biosensors-03-00286-f001: SEM images of fibers with polymer coating at 5,000× magnification. (A) 3TAA concentration of 10 mg/mL. A smooth conformal polymer coating was observed along the individual fibers with minimal polymer clusters. (B) 3TAA concentration of 100 mg/mL. The coating is rough, with a large amount of polymer built up along the surface, engulfing several fibers and reducing the porosity of the membrane.

Mentions: The increase in concentration of 3TAA in the polymerization process resulted in an increase in the buildup of the coating on the polypropylene fibers. Little visible difference was observed between the samples ranging in concentration from 0–10 mg/mL. The four samples tested within this range showed a conformal polymer coating around the individual polypropylene fibers. Along the fibers, small buildup of polymer could be observed. An example of this can be seen in Figure 1(A), where fibers were coated with a concentration of 10 mg/mL. Samples with higher 3TAA concentration displayed large buildups of polymer that had collected together to form aggregates measuring roughly 400–500 µm in diameter on the fiber surface. As seen in Figure 1(B), fibers coated at a concentration of 100 mg/mL show polymer build up along the surface, engulfing several fibers and reducing the porosity of the membrane instead of forming a smooth conformal polymer coating along the individual fibers. It was also observed that as the concentration of 3TAA was increased, the polymer coating became more brittle. Flakes of polymer fell off of the samples containing 50 and 100 mg/mL when handled.


The effect of 3-thiopheneacetic Acid in the polymerization of a conductive electrotextile for use in biosensor development.

McGraw SK, Alocilja E, Senecal A, Senecal K - Biosensors (Basel) (2013)

SEM images of fibers with polymer coating at 5,000× magnification. (A) 3TAA concentration of 10 mg/mL. A smooth conformal polymer coating was observed along the individual fibers with minimal polymer clusters. (B) 3TAA concentration of 100 mg/mL. The coating is rough, with a large amount of polymer built up along the surface, engulfing several fibers and reducing the porosity of the membrane.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4263581&req=5

biosensors-03-00286-f001: SEM images of fibers with polymer coating at 5,000× magnification. (A) 3TAA concentration of 10 mg/mL. A smooth conformal polymer coating was observed along the individual fibers with minimal polymer clusters. (B) 3TAA concentration of 100 mg/mL. The coating is rough, with a large amount of polymer built up along the surface, engulfing several fibers and reducing the porosity of the membrane.
Mentions: The increase in concentration of 3TAA in the polymerization process resulted in an increase in the buildup of the coating on the polypropylene fibers. Little visible difference was observed between the samples ranging in concentration from 0–10 mg/mL. The four samples tested within this range showed a conformal polymer coating around the individual polypropylene fibers. Along the fibers, small buildup of polymer could be observed. An example of this can be seen in Figure 1(A), where fibers were coated with a concentration of 10 mg/mL. Samples with higher 3TAA concentration displayed large buildups of polymer that had collected together to form aggregates measuring roughly 400–500 µm in diameter on the fiber surface. As seen in Figure 1(B), fibers coated at a concentration of 100 mg/mL show polymer build up along the surface, engulfing several fibers and reducing the porosity of the membrane instead of forming a smooth conformal polymer coating along the individual fibers. It was also observed that as the concentration of 3TAA was increased, the polymer coating became more brittle. Flakes of polymer fell off of the samples containing 50 and 100 mg/mL when handled.

Bottom Line: The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites.It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements.A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

View Article: PubMed Central - PubMed

Affiliation: Biosystems and Agricultural Engineering, Michigan State University, 524 S. Shaw Lane, 115 Farrall Hall, East Lansing, MI 48824, USA. shannon.k.mcgraw2.civ@mail.mil.

ABSTRACT
Investigations were conducted to develop an electrotextile using a nonwoven polypropylene fiber platform conformally coated in a conductive, functionalized copolymer of polypyrrole and 3-thiopheneacetic acid (3TAA). The objectives of this study were to determine: (1) if the inclusion of 3TAA in the polymerization process would have an effect on the availability of binding sites in the high-surface area electrotextile for biorecognition elements and (2) how the increase in the concentration of 3TAA would affect the physical characteristics of the coating, resistivity of the sample and availability of binding sites. It was found that the addition of 3TAA to the polymerization process resulted in an increase in the size of the polypyrrole coating, as well as the material resistivity and available binding sites for biorecognition elements. These factors were used to determine which of the tested concentrations was best for biosensor development. A polymer coated membrane sample containing a concentration within the range of 10-50 mg/mL of 3TAA was selected as the best for future biosensor work.

No MeSH data available.