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The electronic cigarette: the new cigarette of the 21st century?

Knorst MM, Benedetto IG, Hoffmeister MC, Gazzana MB - J Bras Pneumol (2014)

Bottom Line: The electronic nicotine delivery system, also known as the electronic cigarette, is generating considerable controversy, not only in the general population but also among health professionals.There are few available data regarding the safety of electronic cigarettes.In addition, the increasing use of electronic cigarettes by adolescents is a cause for concern.

View Article: PubMed Central - PubMed

Affiliation: School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

ABSTRACT
The electronic nicotine delivery system, also known as the electronic cigarette, is generating considerable controversy, not only in the general population but also among health professionals. Smokers the world over have been increasingly using electronic cigarettes as an aid to smoking cessation and as a substitute for conventional cigarettes. There are few available data regarding the safety of electronic cigarettes. There is as yet no evidence that electronic cigarettes are effective in treating nicotine addiction. Some smokers have reported using electronic cigarettes for over a year, often combined with conventional cigarettes, thus prolonging nicotine addiction. In addition, the increasing use of electronic cigarettes by adolescents is a cause for concern. The objective of this study was to describe electronic cigarettes and their components, as well as to review the literature regarding their safety; their impact on smoking initiation and smoking cessation; and regulatory issues related to their use.

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Related in: MedlinePlus

Clinical studies evaluating the effects of electronic cigarettes on smokingreduction and smoking cessation. CO: carbon monoxide; EC: electronic cigarette;and G1, G2, and G3: groups 1, 2, and 3.
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f02: Clinical studies evaluating the effects of electronic cigarettes on smokingreduction and smoking cessation. CO: carbon monoxide; EC: electronic cigarette;and G1, G2, and G3: groups 1, 2, and 3.

Mentions: Few studies have evaluated the effects of EC use on smoking reduction and cessationwithin 6-24 months. Two randomized controlled clinical trials and three prospectivebefore-and-after studies are described in Chart 1.One of the clinical trials(13) compared a 16-mg nicotine EC with 21-mg nicotine patches and anicotine-free EC, whereas the other(40) compared a 7.2-mg nicotine EC with a nicotine-free EC. Both trials lasted12 weeks, and neither found significant differences between groups in terms of smokingreduction or smoking cessation rates at 6 or 12 months. (13,40) The three prospective uncontrolled studies involved a small number ofsmokers unwilling to quit (one of the groups consisting of schizophrenic patients) andfound smoking cessation rates of 22.5%, 14.3%, and 12.5% at 6 months, 12 months, and 24months, respectively.(38,39,41) In addition, an online survey of 5,000 individuals who had purchased aparticular brand of ECs was conducted 7 months after the purchase and showed high ratesof smoking reduction (66.8%) and smoking cessation (31.0%) at 6 months among the 222questionnaire respondents.(54) However, one limitation of that study was that the survey response rate waslow, i.e., 4.5%; if the survey nonrespondents were to be considered smokers, the smokingcessation rate would be 1.4%.(54)


The electronic cigarette: the new cigarette of the 21st century?

Knorst MM, Benedetto IG, Hoffmeister MC, Gazzana MB - J Bras Pneumol (2014)

Clinical studies evaluating the effects of electronic cigarettes on smokingreduction and smoking cessation. CO: carbon monoxide; EC: electronic cigarette;and G1, G2, and G3: groups 1, 2, and 3.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4263338&req=5

f02: Clinical studies evaluating the effects of electronic cigarettes on smokingreduction and smoking cessation. CO: carbon monoxide; EC: electronic cigarette;and G1, G2, and G3: groups 1, 2, and 3.
Mentions: Few studies have evaluated the effects of EC use on smoking reduction and cessationwithin 6-24 months. Two randomized controlled clinical trials and three prospectivebefore-and-after studies are described in Chart 1.One of the clinical trials(13) compared a 16-mg nicotine EC with 21-mg nicotine patches and anicotine-free EC, whereas the other(40) compared a 7.2-mg nicotine EC with a nicotine-free EC. Both trials lasted12 weeks, and neither found significant differences between groups in terms of smokingreduction or smoking cessation rates at 6 or 12 months. (13,40) The three prospective uncontrolled studies involved a small number ofsmokers unwilling to quit (one of the groups consisting of schizophrenic patients) andfound smoking cessation rates of 22.5%, 14.3%, and 12.5% at 6 months, 12 months, and 24months, respectively.(38,39,41) In addition, an online survey of 5,000 individuals who had purchased aparticular brand of ECs was conducted 7 months after the purchase and showed high ratesof smoking reduction (66.8%) and smoking cessation (31.0%) at 6 months among the 222questionnaire respondents.(54) However, one limitation of that study was that the survey response rate waslow, i.e., 4.5%; if the survey nonrespondents were to be considered smokers, the smokingcessation rate would be 1.4%.(54)

Bottom Line: The electronic nicotine delivery system, also known as the electronic cigarette, is generating considerable controversy, not only in the general population but also among health professionals.There are few available data regarding the safety of electronic cigarettes.In addition, the increasing use of electronic cigarettes by adolescents is a cause for concern.

View Article: PubMed Central - PubMed

Affiliation: School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

ABSTRACT
The electronic nicotine delivery system, also known as the electronic cigarette, is generating considerable controversy, not only in the general population but also among health professionals. Smokers the world over have been increasingly using electronic cigarettes as an aid to smoking cessation and as a substitute for conventional cigarettes. There are few available data regarding the safety of electronic cigarettes. There is as yet no evidence that electronic cigarettes are effective in treating nicotine addiction. Some smokers have reported using electronic cigarettes for over a year, often combined with conventional cigarettes, thus prolonging nicotine addiction. In addition, the increasing use of electronic cigarettes by adolescents is a cause for concern. The objective of this study was to describe electronic cigarettes and their components, as well as to review the literature regarding their safety; their impact on smoking initiation and smoking cessation; and regulatory issues related to their use.

Show MeSH
Related in: MedlinePlus