Tension force-induced ATP promotes osteogenesis through P2X7 receptor in osteoblasts.
Bottom Line: TF significantly increased extracellular ATP release compared to control.Six percent TF had maximum effect on ATP release compared to 18% TF and control.A438079 blocked the stimulatory effect of 6% TF on the expression of Runx2, Osterix and ECMPs, ALP activity, and calcium content in ECM.
Affiliation: Nihon University Graduate School of Dentistry, Tokyo, Japan.Show MeSH
Related in: MedlinePlus
Affiliation: Nihon University Graduate School of Dentistry, Tokyo, Japan.