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The cumulative incidence of conventional risk factors of cardiovascular disease and their population attributable risk in an Iranian population: The Isfahan Cohort Study.

Sadeghi M, Talaei M, Oveisgharan S, Rabiei K, Dianatkhah M, Bahonar A, Sarrafzadegan N - Adv Biomed Res (2014)

Bottom Line: Among those with overweight or obesity, 14.7% of men and 7.9% of women decreased their weight up to the normal level.The present study revealed a high incidence of CVD risk factors especially dyslipidemia, obesity, MetS and HTN.Therefore, the application of life-style modification interventions seems necessary.

View Article: PubMed Central - PubMed

Affiliation: Cardiac Rehabilitation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: Cardiovascular diseases (CVDs) are the leading cause of death in Iran. The present study evaluated the 7-year incidence of CVD risk factors among the participants of Isfahan cohort study (ICS).

Materials and methods: ICS was a longitudinal study on adults over 35 years of age from the urban and rural areas in three counties in central Iran. Data on clinical examination and blood measurements were collected in 2001. Subjects were followed and similar data were collected in 2007. Cumulative incidence was calculated through dividing new cases of each risk factor by the population free of that risk factor at baseline. Incidence proportion was determined for major CVD risk factors including hypertension (HTN), hypercholesterolemia (HC), hypertriglyceridemia (HTg), obesity, diabetes mellitus (DM), metabolic syndrome (MetS), and smoking.

Results: A total number of 6323 adults free of CVDs were recruited. After 7 years of follow-up, 3283 individuals were re-evaluated in 2007. The participants' age was 49.2 ± 10.3 years in 2001 (mean ± SD). The 7-year cumulative incidence of HTN, HC, HTg, overweight, obesity, DM, MetS, and smoking was 22.8%, 37.4%, 28.0%, 26.3%, 7.4%, 9.5%, 23.9%, and 5.9% in men and 22.2%, 55.4%, 33.5%, 35.0%, 18.8%, 11.3%, 36.1%, and 0.7% in women, respectively. Among those with overweight or obesity, 14.7% of men and 7.9% of women decreased their weight up to the normal level.

Conclusions: The present study revealed a high incidence of CVD risk factors especially dyslipidemia, obesity, MetS and HTN. Therefore, the application of life-style modification interventions seems necessary.

No MeSH data available.


Related in: MedlinePlus

Study algorithm
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Figure 1: Study algorithm

Mentions: At baseline evaluation (2001), 100 (3.2%) men and 81 (2.4%) women reported a history of CVD and were excluded from all further analyses. Among 6323 participants free of CVD, who aged 50.7 ± 11.6 years (mean ± SD) and 3255 (51.5%) were women, laboratory measurements and physical examinations were performed for 3283 participants in 2007 [Figure 1]. The average age of subjects with complete measurements in both assessments was increased from 49.2 ± 10.3 years in 2001 to 55.9 ± 10.4 in 2007, and 1679 (51.2%) of participants were women.


The cumulative incidence of conventional risk factors of cardiovascular disease and their population attributable risk in an Iranian population: The Isfahan Cohort Study.

Sadeghi M, Talaei M, Oveisgharan S, Rabiei K, Dianatkhah M, Bahonar A, Sarrafzadegan N - Adv Biomed Res (2014)

Study algorithm
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260292&req=5

Figure 1: Study algorithm
Mentions: At baseline evaluation (2001), 100 (3.2%) men and 81 (2.4%) women reported a history of CVD and were excluded from all further analyses. Among 6323 participants free of CVD, who aged 50.7 ± 11.6 years (mean ± SD) and 3255 (51.5%) were women, laboratory measurements and physical examinations were performed for 3283 participants in 2007 [Figure 1]. The average age of subjects with complete measurements in both assessments was increased from 49.2 ± 10.3 years in 2001 to 55.9 ± 10.4 in 2007, and 1679 (51.2%) of participants were women.

Bottom Line: Among those with overweight or obesity, 14.7% of men and 7.9% of women decreased their weight up to the normal level.The present study revealed a high incidence of CVD risk factors especially dyslipidemia, obesity, MetS and HTN.Therefore, the application of life-style modification interventions seems necessary.

View Article: PubMed Central - PubMed

Affiliation: Cardiac Rehabilitation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: Cardiovascular diseases (CVDs) are the leading cause of death in Iran. The present study evaluated the 7-year incidence of CVD risk factors among the participants of Isfahan cohort study (ICS).

Materials and methods: ICS was a longitudinal study on adults over 35 years of age from the urban and rural areas in three counties in central Iran. Data on clinical examination and blood measurements were collected in 2001. Subjects were followed and similar data were collected in 2007. Cumulative incidence was calculated through dividing new cases of each risk factor by the population free of that risk factor at baseline. Incidence proportion was determined for major CVD risk factors including hypertension (HTN), hypercholesterolemia (HC), hypertriglyceridemia (HTg), obesity, diabetes mellitus (DM), metabolic syndrome (MetS), and smoking.

Results: A total number of 6323 adults free of CVDs were recruited. After 7 years of follow-up, 3283 individuals were re-evaluated in 2007. The participants' age was 49.2 ± 10.3 years in 2001 (mean ± SD). The 7-year cumulative incidence of HTN, HC, HTg, overweight, obesity, DM, MetS, and smoking was 22.8%, 37.4%, 28.0%, 26.3%, 7.4%, 9.5%, 23.9%, and 5.9% in men and 22.2%, 55.4%, 33.5%, 35.0%, 18.8%, 11.3%, 36.1%, and 0.7% in women, respectively. Among those with overweight or obesity, 14.7% of men and 7.9% of women decreased their weight up to the normal level.

Conclusions: The present study revealed a high incidence of CVD risk factors especially dyslipidemia, obesity, MetS and HTN. Therefore, the application of life-style modification interventions seems necessary.

No MeSH data available.


Related in: MedlinePlus