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Primary actinomycosis of hand.

Padhi S, Dash M, Turuk J, Sahu R, Panda P - Adv Biomed Res (2014)

Bottom Line: Actinomycosis is a chronic granulomatous suppurative disease having the propensity for extension to the contagious tissue with the formation of multiple discharging sinus tracts.Primary actinomycosis of extremity is a very uncommon clinical entity and is commonly considered as a soft-tissue infection.We report here, a case of primary actinomycosis of the upper extremity in a 24-year-old male who was treated successfully with surgical excision and extended period of antimicrobial treatment.

View Article: PubMed Central - PubMed

Affiliation: Department of Microbiology, M.K.C.G Medical College and Hospital, Berhampur, Odisha, India.

ABSTRACT
Actinomycosis is a chronic granulomatous suppurative disease having the propensity for extension to the contagious tissue with the formation of multiple discharging sinus tracts. Primary actinomycosis of extremity is a very uncommon clinical entity and is commonly considered as a soft-tissue infection. We report here, a case of primary actinomycosis of the upper extremity in a 24-year-old male who was treated successfully with surgical excision and extended period of antimicrobial treatment.

No MeSH data available.


Related in: MedlinePlus

Histopathological study showing radiating filaments, surrounded by eosinophilic hyaline material
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Figure 3: Histopathological study showing radiating filaments, surrounded by eosinophilic hyaline material

Mentions: An initial clinical diagnosis of tuberculosis was made due to endemicity of the disease in Odisha, India. The routine biochemical and hematological tests including erythrocyte sedimentation rate were within the normal range. The X-ray of the upper extremity revealed no significant abnormalities. Swabs collected from the discharging sinuses were subjected to microbiological studies. Few pus cells and no bacteria were detected in the microscopy. Microbiological cultures for aerobic and anaerobic organisms showed growth of only Staphylococcus aureus which was sensitive to linezolid. Based on acid fast staining and culture, tuberculosis was ruled out. Hence, patient was advised with oral 600 mg of linezolid twice daily for 10 days, which yielded only a partial, but not complete relief. Finally, curettage and biopsy of the draining sinuses was made, which revealed many neutrophils with some colonies consisting of radiating filaments, surrounded by eosinophilic hyaline material creating a sun-ray pattern, similar to that of actinomycosis [Figure 3]. There was no evidence of lung disease, tooth problems or gingivitis in patient. Hence, a diagnosis of primary actinomycosis of hand was made for which he was treated with surgical debridement [Figure 4] and intravenous and oral penicillin therapy for 6 months to which patient showed excellent response.


Primary actinomycosis of hand.

Padhi S, Dash M, Turuk J, Sahu R, Panda P - Adv Biomed Res (2014)

Histopathological study showing radiating filaments, surrounded by eosinophilic hyaline material
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260285&req=5

Figure 3: Histopathological study showing radiating filaments, surrounded by eosinophilic hyaline material
Mentions: An initial clinical diagnosis of tuberculosis was made due to endemicity of the disease in Odisha, India. The routine biochemical and hematological tests including erythrocyte sedimentation rate were within the normal range. The X-ray of the upper extremity revealed no significant abnormalities. Swabs collected from the discharging sinuses were subjected to microbiological studies. Few pus cells and no bacteria were detected in the microscopy. Microbiological cultures for aerobic and anaerobic organisms showed growth of only Staphylococcus aureus which was sensitive to linezolid. Based on acid fast staining and culture, tuberculosis was ruled out. Hence, patient was advised with oral 600 mg of linezolid twice daily for 10 days, which yielded only a partial, but not complete relief. Finally, curettage and biopsy of the draining sinuses was made, which revealed many neutrophils with some colonies consisting of radiating filaments, surrounded by eosinophilic hyaline material creating a sun-ray pattern, similar to that of actinomycosis [Figure 3]. There was no evidence of lung disease, tooth problems or gingivitis in patient. Hence, a diagnosis of primary actinomycosis of hand was made for which he was treated with surgical debridement [Figure 4] and intravenous and oral penicillin therapy for 6 months to which patient showed excellent response.

Bottom Line: Actinomycosis is a chronic granulomatous suppurative disease having the propensity for extension to the contagious tissue with the formation of multiple discharging sinus tracts.Primary actinomycosis of extremity is a very uncommon clinical entity and is commonly considered as a soft-tissue infection.We report here, a case of primary actinomycosis of the upper extremity in a 24-year-old male who was treated successfully with surgical excision and extended period of antimicrobial treatment.

View Article: PubMed Central - PubMed

Affiliation: Department of Microbiology, M.K.C.G Medical College and Hospital, Berhampur, Odisha, India.

ABSTRACT
Actinomycosis is a chronic granulomatous suppurative disease having the propensity for extension to the contagious tissue with the formation of multiple discharging sinus tracts. Primary actinomycosis of extremity is a very uncommon clinical entity and is commonly considered as a soft-tissue infection. We report here, a case of primary actinomycosis of the upper extremity in a 24-year-old male who was treated successfully with surgical excision and extended period of antimicrobial treatment.

No MeSH data available.


Related in: MedlinePlus