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Chromium level in prediction of diabetes in pre-diabetic patients.

Rafiei R, Habyby Z, Fouladi L, Najafi S, Asgary S, Torabi Z - Adv Biomed Res (2014)

Bottom Line: Chromium supplementations (Cr) have been shown to exert beneficial effects in the management of type-2 diabetes.No significant differences in age, BMI, FBS or insulin were observed between two groups.In the group with a normal level of Cr, there was a significant reversed correlation between the Cr level and age, but no significant correlation existed between the Cr level and other factors in both groups.

View Article: PubMed Central - PubMed

Affiliation: Islamic Azad University, Najafabad, Iran.

ABSTRACT

Background: Chromium supplementations (Cr) have been shown to exert beneficial effects in the management of type-2 diabetes. Prevalence of Cr deficiency in pre-diabetic patients is not well-understood, therefore, the aim of this study was to evaluate the extent of this prevalence.

Materials and methods: In this cross-sectional descriptive study, 132 pre-diabetic patients were recruited. The participants were randomly selected from those who referred to the Shariati Hospital in Isfahan, Iran. Blood samples are collected for measurement of Cr, insulin, fasting blood sugar (FBS), and two-hour post-load plasma glucose. The body mass index (BMI) was calculated. Determination of Cr was carried out by atomic absorption spectrometry.

Results: Thirty-four (31.5%) patients had Cr deficiency and 74 (68.5%) patients had normal Cr. There was no significant difference between sex, age groups (<50 years and ≥50 years) and between patients with and without a family history of diabetes in both the groups. No significant differences in age, BMI, FBS or insulin were observed between two groups. In the group with a normal level of Cr, there was a significant reversed correlation between the Cr level and age, but no significant correlation existed between the Cr level and other factors in both groups.

Conclusion: The levels of Cr deficiency are relatively common in patients with pre-diabetes, and it is necessary to screen patients with diabetes and pre-diabetes according to the American Diabetes Association guidelines, with regard to the Cr level and action should be taken to eliminate the Cr deficiency in these patients.

No MeSH data available.


Related in: MedlinePlus

The Cr levels (μg/L) based on sex in two normal Cr and Cr-deficiency groups
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Related In: Results  -  Collection

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Figure 1: The Cr levels (μg/L) based on sex in two normal Cr and Cr-deficiency groups

Mentions: According to the findings, as shown in Table 2 and Figures 1–3, no significant difference was observed in age and BMI, as well as FBS and insulin, between the two groups. Cr deficiency occured at higher levels of FBS and BMI, but at older ages they were not statistically significant.


Chromium level in prediction of diabetes in pre-diabetic patients.

Rafiei R, Habyby Z, Fouladi L, Najafi S, Asgary S, Torabi Z - Adv Biomed Res (2014)

The Cr levels (μg/L) based on sex in two normal Cr and Cr-deficiency groups
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260284&req=5

Figure 1: The Cr levels (μg/L) based on sex in two normal Cr and Cr-deficiency groups
Mentions: According to the findings, as shown in Table 2 and Figures 1–3, no significant difference was observed in age and BMI, as well as FBS and insulin, between the two groups. Cr deficiency occured at higher levels of FBS and BMI, but at older ages they were not statistically significant.

Bottom Line: Chromium supplementations (Cr) have been shown to exert beneficial effects in the management of type-2 diabetes.No significant differences in age, BMI, FBS or insulin were observed between two groups.In the group with a normal level of Cr, there was a significant reversed correlation between the Cr level and age, but no significant correlation existed between the Cr level and other factors in both groups.

View Article: PubMed Central - PubMed

Affiliation: Islamic Azad University, Najafabad, Iran.

ABSTRACT

Background: Chromium supplementations (Cr) have been shown to exert beneficial effects in the management of type-2 diabetes. Prevalence of Cr deficiency in pre-diabetic patients is not well-understood, therefore, the aim of this study was to evaluate the extent of this prevalence.

Materials and methods: In this cross-sectional descriptive study, 132 pre-diabetic patients were recruited. The participants were randomly selected from those who referred to the Shariati Hospital in Isfahan, Iran. Blood samples are collected for measurement of Cr, insulin, fasting blood sugar (FBS), and two-hour post-load plasma glucose. The body mass index (BMI) was calculated. Determination of Cr was carried out by atomic absorption spectrometry.

Results: Thirty-four (31.5%) patients had Cr deficiency and 74 (68.5%) patients had normal Cr. There was no significant difference between sex, age groups (<50 years and ≥50 years) and between patients with and without a family history of diabetes in both the groups. No significant differences in age, BMI, FBS or insulin were observed between two groups. In the group with a normal level of Cr, there was a significant reversed correlation between the Cr level and age, but no significant correlation existed between the Cr level and other factors in both groups.

Conclusion: The levels of Cr deficiency are relatively common in patients with pre-diabetes, and it is necessary to screen patients with diabetes and pre-diabetes according to the American Diabetes Association guidelines, with regard to the Cr level and action should be taken to eliminate the Cr deficiency in these patients.

No MeSH data available.


Related in: MedlinePlus