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Percutaneous nephrolithotomy: Effect of unilateral procedure on contralateral kidney function.

Sichani MM, Behnamfar A, Khorami MH, Nourimahdavi K, Alizadeh F, Izadpanahi MH - Adv Biomed Res (2014)

Bottom Line: From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL.Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side.During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: Although long-term effects of percutaneous nephrolithotomy (PCNL) on renal function and structure have been evaluated, knowledge regarding the immediate effects of surgery on renal function is limited. We conducted this study to evaluate the impact of unilateral PCNL on bilateral renal function during immediate post-operative period.

Materials and methods: From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL. During the post-operative period, creatinine clearances (CrCl) of treated and untreated sides were estimated separately and pattern of changes in bilateral renal function following this procedure was evaluated.

Results: Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side. We observed progressive decline in CrCl of both sides followed by bilateral improvement in renal function toward pre-operative values.

Conclusions: During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.

No MeSH data available.


Related in: MedlinePlus

Pattern of changes in estimated glomerular filtration rate of both kidneys following percutaneous nephrolithotomy
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Figure 1: Pattern of changes in estimated glomerular filtration rate of both kidneys following percutaneous nephrolithotomy

Mentions: Mean pre-operative GFR of each kidney was estimated to be 68.2. Table 2 shows the eGFR of both kidneys for a period of 72 h post-operatively. Pattern of changes in eGFR of both kidneys are shown in Figure 1.


Percutaneous nephrolithotomy: Effect of unilateral procedure on contralateral kidney function.

Sichani MM, Behnamfar A, Khorami MH, Nourimahdavi K, Alizadeh F, Izadpanahi MH - Adv Biomed Res (2014)

Pattern of changes in estimated glomerular filtration rate of both kidneys following percutaneous nephrolithotomy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260279&req=5

Figure 1: Pattern of changes in estimated glomerular filtration rate of both kidneys following percutaneous nephrolithotomy
Mentions: Mean pre-operative GFR of each kidney was estimated to be 68.2. Table 2 shows the eGFR of both kidneys for a period of 72 h post-operatively. Pattern of changes in eGFR of both kidneys are shown in Figure 1.

Bottom Line: From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL.Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side.During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: Although long-term effects of percutaneous nephrolithotomy (PCNL) on renal function and structure have been evaluated, knowledge regarding the immediate effects of surgery on renal function is limited. We conducted this study to evaluate the impact of unilateral PCNL on bilateral renal function during immediate post-operative period.

Materials and methods: From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL. During the post-operative period, creatinine clearances (CrCl) of treated and untreated sides were estimated separately and pattern of changes in bilateral renal function following this procedure was evaluated.

Results: Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side. We observed progressive decline in CrCl of both sides followed by bilateral improvement in renal function toward pre-operative values.

Conclusions: During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.

No MeSH data available.


Related in: MedlinePlus