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Association of depression with type 2 diabetes and relevant factors.

Kalantari S, Jafarinezhad A, Zohrevand B - Adv Biomed Res (2014)

Bottom Line: Information on demographic and clinical and paraclinical characteristics was collected by interviews and from medical records.This cross-sectional study was performed on 90 type 2 diabetic patients (63 female and 27 male with a mean age of 54.17 ± 10.57 years) and 90 healthy matched controls.Diabetes itself was the only significant determinant of having depression after matching with other variables.

View Article: PubMed Central - PubMed

Affiliation: Department of Endocrinology, Guilan University of Medical Sciences, Rasht, Iran.

ABSTRACT

Background: Based on the high prevalence of diabetes and depression in Rasht, we conducted a study to evaluate the prevalence of depression in type 2 diabetic patients, and its association with glycemic control, chronic complications, and some clinical and paraclinical parameters in this northern state of Iran.

Materials and methods: Beck depression inventory was used for evaluating depression on 90 type 2 diabetics and 90 healthy controls selected. Information on demographic and clinical and paraclinical characteristics was collected by interviews and from medical records.

Results: This cross-sectional study was performed on 90 type 2 diabetic patients (63 female and 27 male with a mean age of 54.17 ± 10.57 years) and 90 healthy matched controls. Overall, depression was significantly more prevalent in case group [37.8% vs. 16%, odds ratio (OR) = 3.29, P = 0.001]. The prevalence of depression in diabetic women was significantly higher than nondiabetic ones (39.7% vs. 15%, P = 0.002). We could not find any significant correlation between depression and positive family history of depression, duration of diabetes, HBA1c level, and body mass index. The prevalence of depression was prominently more in diabetic patients with retinopathy than in those without this complication (55.6% vs. 24%, P = 0.015). Logistic regression analysis indicated that diabetes itself was the only significant determinant of having depression (OR = 3.29, P = 0.005, 95% confidence interval: 0.118-0.667).

Conclusion: There was a prominent prevalence of depression in type 2 diabetics overall. Depression was not correlated with duration of diabetes and glycemic control. There was a significant association between depression and retinopathy in diabetic patients. Diabetes itself was the only significant determinant of having depression after matching with other variables.

No MeSH data available.


Related in: MedlinePlus

The distribution of depression in the case and control group
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Figure 1: The distribution of depression in the case and control group

Mentions: There were 90 cases, 63 (70%) females and 27 (30%) males and 90 matched controls recruited in the study. The demographic features of subjects are shown in table 1. In the case group mild, moderate, and severe depression was detected in 30%, 5.6%, and 2.2% of the patients, respectively, whereas in control group mild depression was observed in 11%, moderate depression in 3%, and severe depression in 2%. Overall depression was significantly more prevalent in case group [37.8% vs. 16%, odds ratio (OR) =3.29, P = 0.001]. The distribution of depression in the case and control groups is illustrated in Figure 1.


Association of depression with type 2 diabetes and relevant factors.

Kalantari S, Jafarinezhad A, Zohrevand B - Adv Biomed Res (2014)

The distribution of depression in the case and control group
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260271&req=5

Figure 1: The distribution of depression in the case and control group
Mentions: There were 90 cases, 63 (70%) females and 27 (30%) males and 90 matched controls recruited in the study. The demographic features of subjects are shown in table 1. In the case group mild, moderate, and severe depression was detected in 30%, 5.6%, and 2.2% of the patients, respectively, whereas in control group mild depression was observed in 11%, moderate depression in 3%, and severe depression in 2%. Overall depression was significantly more prevalent in case group [37.8% vs. 16%, odds ratio (OR) =3.29, P = 0.001]. The distribution of depression in the case and control groups is illustrated in Figure 1.

Bottom Line: Information on demographic and clinical and paraclinical characteristics was collected by interviews and from medical records.This cross-sectional study was performed on 90 type 2 diabetic patients (63 female and 27 male with a mean age of 54.17 ± 10.57 years) and 90 healthy matched controls.Diabetes itself was the only significant determinant of having depression after matching with other variables.

View Article: PubMed Central - PubMed

Affiliation: Department of Endocrinology, Guilan University of Medical Sciences, Rasht, Iran.

ABSTRACT

Background: Based on the high prevalence of diabetes and depression in Rasht, we conducted a study to evaluate the prevalence of depression in type 2 diabetic patients, and its association with glycemic control, chronic complications, and some clinical and paraclinical parameters in this northern state of Iran.

Materials and methods: Beck depression inventory was used for evaluating depression on 90 type 2 diabetics and 90 healthy controls selected. Information on demographic and clinical and paraclinical characteristics was collected by interviews and from medical records.

Results: This cross-sectional study was performed on 90 type 2 diabetic patients (63 female and 27 male with a mean age of 54.17 ± 10.57 years) and 90 healthy matched controls. Overall, depression was significantly more prevalent in case group [37.8% vs. 16%, odds ratio (OR) = 3.29, P = 0.001]. The prevalence of depression in diabetic women was significantly higher than nondiabetic ones (39.7% vs. 15%, P = 0.002). We could not find any significant correlation between depression and positive family history of depression, duration of diabetes, HBA1c level, and body mass index. The prevalence of depression was prominently more in diabetic patients with retinopathy than in those without this complication (55.6% vs. 24%, P = 0.015). Logistic regression analysis indicated that diabetes itself was the only significant determinant of having depression (OR = 3.29, P = 0.005, 95% confidence interval: 0.118-0.667).

Conclusion: There was a prominent prevalence of depression in type 2 diabetics overall. Depression was not correlated with duration of diabetes and glycemic control. There was a significant association between depression and retinopathy in diabetic patients. Diabetes itself was the only significant determinant of having depression after matching with other variables.

No MeSH data available.


Related in: MedlinePlus