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Ultrasensitive non-enzymatic glucose sensor based on three-dimensional network of ZnO-CuO hierarchical nanocomposites by electrospinning.

Zhou C, Xu L, Song J, Xing R, Xu S, Liu D, Song H - Sci Rep (2014)

Bottom Line: Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes.Moreover, a good synergetic effect between CuO and ZnO was confirmed.The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.

ABSTRACT
Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes. The structural characterization revealed that the ZnO-CuO HNCs were composed of the ZnO and CuO mixed NWs trunk (~200 nm), whose outer surface was attached with small CuO nanoparticles (NPs). Moreover, a good synergetic effect between CuO and ZnO was confirmed. The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs. At an applied potential of + 0.7 V, the optimum ZnO-CuO HNCs electrode presented a high sensitivity of 3066.4 μAmM(-1)cm(-2), the linear range up to 1.6 mM, and low practical detection limit of 0.21 μM. It also showed outstanding long term stability, good reproducibility, excellent selectivity and accurate measurement in real serum sample. The formation of special hierarchical heterojunction and the well-constructed 3D structure were the main reasons for the enhanced nonenzymatic biosensing behavior.

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CV curves of the 3D porous ZnO–CuO HNCs at various scan rates (50, 100, 150, 200, and 250 mV/s), inset is the plots of peak current vs. scan rate.
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f7: CV curves of the 3D porous ZnO–CuO HNCs at various scan rates (50, 100, 150, 200, and 250 mV/s), inset is the plots of peak current vs. scan rate.

Mentions: Moreover, as can be seen in Fig. 5c, the peak current intensity increases gradually when the electrospun time changes from 10 min to 20 min and then decreases when electrospun time further increased to 25 min. That is to say, whatever comparing to 3D mixed ZnO/CuO NWs and pure CuO NWs electrodes with the same electrospun time (20 min) or the other 3D porous ZnO–CuO HNCs electrodes with different thickness, the 3D porous ZnO–CuO HNCs electrode (20 min) always exhibits the best electrochemistry behavior. This phenomenon indicates that a reasonable-built and well-structured 3D structure can effectively accelerate the electron transfer. In addition, The CV measurement of 3D porous ZnO–CuO HNCs (20 min) electrode was further performed in 0.1 M NaOH solution at different scan rates (Fig. 7). The peak current shows a linear response to the scan rate, implying a surface-controlled electrochemical process7.


Ultrasensitive non-enzymatic glucose sensor based on three-dimensional network of ZnO-CuO hierarchical nanocomposites by electrospinning.

Zhou C, Xu L, Song J, Xing R, Xu S, Liu D, Song H - Sci Rep (2014)

CV curves of the 3D porous ZnO–CuO HNCs at various scan rates (50, 100, 150, 200, and 250 mV/s), inset is the plots of peak current vs. scan rate.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260231&req=5

f7: CV curves of the 3D porous ZnO–CuO HNCs at various scan rates (50, 100, 150, 200, and 250 mV/s), inset is the plots of peak current vs. scan rate.
Mentions: Moreover, as can be seen in Fig. 5c, the peak current intensity increases gradually when the electrospun time changes from 10 min to 20 min and then decreases when electrospun time further increased to 25 min. That is to say, whatever comparing to 3D mixed ZnO/CuO NWs and pure CuO NWs electrodes with the same electrospun time (20 min) or the other 3D porous ZnO–CuO HNCs electrodes with different thickness, the 3D porous ZnO–CuO HNCs electrode (20 min) always exhibits the best electrochemistry behavior. This phenomenon indicates that a reasonable-built and well-structured 3D structure can effectively accelerate the electron transfer. In addition, The CV measurement of 3D porous ZnO–CuO HNCs (20 min) electrode was further performed in 0.1 M NaOH solution at different scan rates (Fig. 7). The peak current shows a linear response to the scan rate, implying a surface-controlled electrochemical process7.

Bottom Line: Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes.Moreover, a good synergetic effect between CuO and ZnO was confirmed.The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.

ABSTRACT
Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes. The structural characterization revealed that the ZnO-CuO HNCs were composed of the ZnO and CuO mixed NWs trunk (~200 nm), whose outer surface was attached with small CuO nanoparticles (NPs). Moreover, a good synergetic effect between CuO and ZnO was confirmed. The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs. At an applied potential of + 0.7 V, the optimum ZnO-CuO HNCs electrode presented a high sensitivity of 3066.4 μAmM(-1)cm(-2), the linear range up to 1.6 mM, and low practical detection limit of 0.21 μM. It also showed outstanding long term stability, good reproducibility, excellent selectivity and accurate measurement in real serum sample. The formation of special hierarchical heterojunction and the well-constructed 3D structure were the main reasons for the enhanced nonenzymatic biosensing behavior.

Show MeSH