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Ultrasensitive non-enzymatic glucose sensor based on three-dimensional network of ZnO-CuO hierarchical nanocomposites by electrospinning.

Zhou C, Xu L, Song J, Xing R, Xu S, Liu D, Song H - Sci Rep (2014)

Bottom Line: Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes.Moreover, a good synergetic effect between CuO and ZnO was confirmed.The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.

ABSTRACT
Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes. The structural characterization revealed that the ZnO-CuO HNCs were composed of the ZnO and CuO mixed NWs trunk (~200 nm), whose outer surface was attached with small CuO nanoparticles (NPs). Moreover, a good synergetic effect between CuO and ZnO was confirmed. The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs. At an applied potential of + 0.7 V, the optimum ZnO-CuO HNCs electrode presented a high sensitivity of 3066.4 μAmM(-1)cm(-2), the linear range up to 1.6 mM, and low practical detection limit of 0.21 μM. It also showed outstanding long term stability, good reproducibility, excellent selectivity and accurate measurement in real serum sample. The formation of special hierarchical heterojunction and the well-constructed 3D structure were the main reasons for the enhanced nonenzymatic biosensing behavior.

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(a) Survey, (b) O 1s, (c) Cu 2p, and (d) Zn 2p high resolution XPS spectrum of the corresponding samples.
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f4: (a) Survey, (b) O 1s, (c) Cu 2p, and (d) Zn 2p high resolution XPS spectrum of the corresponding samples.

Mentions: To reveal the surface composition and chemical state of the elements existing in the ZnO–CuO HNCs sample, X-ray photoelectron spectroscopy (XPS) spectra were studied and compared with that of the mixed ZnO/CuO, pure CuO NWs and ZnO NWs as shown in Fig. 4. First, the complete spectra of the samples confirm the presence of Cu, O, and C atoms in pure CuO NWs, Zn, O, and C atoms in pure ZnO NWs and Cu, Zn, O, and C atoms in ZnO–CuO HNCs and mixed ZnO/CuO NWs. Moreover, based on XPS spectra, the atom ratios of Cu/Zn have been quantitatively calculated to be 0.34 and 0.72 corresponding to the mixed ZnO/CuO and ZnO–CuO HNCs samples, respectively. As can be seen, the combination rate is relatively low for CuO in mixed ZnO/CuO, even the initial molar ratio of Zn/Cu is about 0.82. However, although the initial quantity is the same both in the mixed ZnO/CuO and ZnO–CuO HNCs samples, the atom ratio of Cu/Zn is 2.1 times higher in ZnO–CuO HNCs sample than that in mixed ZnO/CuO, this can be attributed to the formation of the special HNCs structure which has CuO NPs decorated on the surface of mixed ZnO/CuO NWs, and thus the atom ratio of Cu/Zn increases.


Ultrasensitive non-enzymatic glucose sensor based on three-dimensional network of ZnO-CuO hierarchical nanocomposites by electrospinning.

Zhou C, Xu L, Song J, Xing R, Xu S, Liu D, Song H - Sci Rep (2014)

(a) Survey, (b) O 1s, (c) Cu 2p, and (d) Zn 2p high resolution XPS spectrum of the corresponding samples.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260231&req=5

f4: (a) Survey, (b) O 1s, (c) Cu 2p, and (d) Zn 2p high resolution XPS spectrum of the corresponding samples.
Mentions: To reveal the surface composition and chemical state of the elements existing in the ZnO–CuO HNCs sample, X-ray photoelectron spectroscopy (XPS) spectra were studied and compared with that of the mixed ZnO/CuO, pure CuO NWs and ZnO NWs as shown in Fig. 4. First, the complete spectra of the samples confirm the presence of Cu, O, and C atoms in pure CuO NWs, Zn, O, and C atoms in pure ZnO NWs and Cu, Zn, O, and C atoms in ZnO–CuO HNCs and mixed ZnO/CuO NWs. Moreover, based on XPS spectra, the atom ratios of Cu/Zn have been quantitatively calculated to be 0.34 and 0.72 corresponding to the mixed ZnO/CuO and ZnO–CuO HNCs samples, respectively. As can be seen, the combination rate is relatively low for CuO in mixed ZnO/CuO, even the initial molar ratio of Zn/Cu is about 0.82. However, although the initial quantity is the same both in the mixed ZnO/CuO and ZnO–CuO HNCs samples, the atom ratio of Cu/Zn is 2.1 times higher in ZnO–CuO HNCs sample than that in mixed ZnO/CuO, this can be attributed to the formation of the special HNCs structure which has CuO NPs decorated on the surface of mixed ZnO/CuO NWs, and thus the atom ratio of Cu/Zn increases.

Bottom Line: Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes.Moreover, a good synergetic effect between CuO and ZnO was confirmed.The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.

ABSTRACT
Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes. The structural characterization revealed that the ZnO-CuO HNCs were composed of the ZnO and CuO mixed NWs trunk (~200 nm), whose outer surface was attached with small CuO nanoparticles (NPs). Moreover, a good synergetic effect between CuO and ZnO was confirmed. The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs. At an applied potential of + 0.7 V, the optimum ZnO-CuO HNCs electrode presented a high sensitivity of 3066.4 μAmM(-1)cm(-2), the linear range up to 1.6 mM, and low practical detection limit of 0.21 μM. It also showed outstanding long term stability, good reproducibility, excellent selectivity and accurate measurement in real serum sample. The formation of special hierarchical heterojunction and the well-constructed 3D structure were the main reasons for the enhanced nonenzymatic biosensing behavior.

Show MeSH