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Ultrasensitive non-enzymatic glucose sensor based on three-dimensional network of ZnO-CuO hierarchical nanocomposites by electrospinning.

Zhou C, Xu L, Song J, Xing R, Xu S, Liu D, Song H - Sci Rep (2014)

Bottom Line: Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes.Moreover, a good synergetic effect between CuO and ZnO was confirmed.The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.

ABSTRACT
Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes. The structural characterization revealed that the ZnO-CuO HNCs were composed of the ZnO and CuO mixed NWs trunk (~200 nm), whose outer surface was attached with small CuO nanoparticles (NPs). Moreover, a good synergetic effect between CuO and ZnO was confirmed. The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs. At an applied potential of + 0.7 V, the optimum ZnO-CuO HNCs electrode presented a high sensitivity of 3066.4 μAmM(-1)cm(-2), the linear range up to 1.6 mM, and low practical detection limit of 0.21 μM. It also showed outstanding long term stability, good reproducibility, excellent selectivity and accurate measurement in real serum sample. The formation of special hierarchical heterojunction and the well-constructed 3D structure were the main reasons for the enhanced nonenzymatic biosensing behavior.

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The XRD of 3D ZnO–CuO HNCs, mixed ZnO/CuO NWs, pure CuO and ZnO NWs samples.The XRD peaks of CuO (JCPDS no.48-1548) are marked with “#” and ZnO (JCPDS no.36-1451) are marked with “*”.
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f1: The XRD of 3D ZnO–CuO HNCs, mixed ZnO/CuO NWs, pure CuO and ZnO NWs samples.The XRD peaks of CuO (JCPDS no.48-1548) are marked with “#” and ZnO (JCPDS no.36-1451) are marked with “*”.

Mentions: The phase characteristics of ZnO–CuO HNCs as well as mixed ZnO/CuO NWs, pure CuO and ZnO NWs were first identified from the X-ray diffraction (XRD) patterns as presented in Fig. 1. The diffraction peaks of the mixed ZnO/CuO NWs and ZnO–CuO HNCs samples are perfectly indexed to the mixture of monoclinic CuO (JCPDS 48-1548) and hexagonal ZnO (JCPDS 36-1451). Besides, the relative intensity of the dominant diffraction peak of CuO is higher than that of ZnO in ZnO–CuO HNCs, suggesting the better crystallinity of CuO in hierarchical sample. However, the situation of crystalline in mixed ZnO/CuO NWs is in the opposite way, which indicated a different arrangement of ZnO and CuO grains in these two samples.


Ultrasensitive non-enzymatic glucose sensor based on three-dimensional network of ZnO-CuO hierarchical nanocomposites by electrospinning.

Zhou C, Xu L, Song J, Xing R, Xu S, Liu D, Song H - Sci Rep (2014)

The XRD of 3D ZnO–CuO HNCs, mixed ZnO/CuO NWs, pure CuO and ZnO NWs samples.The XRD peaks of CuO (JCPDS no.48-1548) are marked with “#” and ZnO (JCPDS no.36-1451) are marked with “*”.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260231&req=5

f1: The XRD of 3D ZnO–CuO HNCs, mixed ZnO/CuO NWs, pure CuO and ZnO NWs samples.The XRD peaks of CuO (JCPDS no.48-1548) are marked with “#” and ZnO (JCPDS no.36-1451) are marked with “*”.
Mentions: The phase characteristics of ZnO–CuO HNCs as well as mixed ZnO/CuO NWs, pure CuO and ZnO NWs were first identified from the X-ray diffraction (XRD) patterns as presented in Fig. 1. The diffraction peaks of the mixed ZnO/CuO NWs and ZnO–CuO HNCs samples are perfectly indexed to the mixture of monoclinic CuO (JCPDS 48-1548) and hexagonal ZnO (JCPDS 36-1451). Besides, the relative intensity of the dominant diffraction peak of CuO is higher than that of ZnO in ZnO–CuO HNCs, suggesting the better crystallinity of CuO in hierarchical sample. However, the situation of crystalline in mixed ZnO/CuO NWs is in the opposite way, which indicated a different arrangement of ZnO and CuO grains in these two samples.

Bottom Line: Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes.Moreover, a good synergetic effect between CuO and ZnO was confirmed.The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs.

View Article: PubMed Central - PubMed

Affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, People's Republic of China.

ABSTRACT
Three-dimensional (3D) porous ZnO-CuO hierarchical nanocomposites (HNCs) nonenzymatic glucose electrodes with different thicknesses were fabricated by coelectrospinning and compared with 3D mixed ZnO/CuO nanowires (NWs) and pure CuO NWs electrodes. The structural characterization revealed that the ZnO-CuO HNCs were composed of the ZnO and CuO mixed NWs trunk (~200 nm), whose outer surface was attached with small CuO nanoparticles (NPs). Moreover, a good synergetic effect between CuO and ZnO was confirmed. The nonenzymatic biosensing properties of as prepared 3D porous electrodes based on fluorine doped tin oxide (FTO) were studied and the results indicated that the sensing properties of 3D porous ZnO-CuO HNCs electrodes were significantly improved and depended strongly on the thickness of the HNCs. At an applied potential of + 0.7 V, the optimum ZnO-CuO HNCs electrode presented a high sensitivity of 3066.4 μAmM(-1)cm(-2), the linear range up to 1.6 mM, and low practical detection limit of 0.21 μM. It also showed outstanding long term stability, good reproducibility, excellent selectivity and accurate measurement in real serum sample. The formation of special hierarchical heterojunction and the well-constructed 3D structure were the main reasons for the enhanced nonenzymatic biosensing behavior.

Show MeSH