Limits...
Gastric squamous papilloma in a 52-year-old female patient.

Jang HH, Kim HW, Kim SJ, Choi CW, Park SB, Song BJ, Shin DH, Kang DH - Clin Endosc (2014)

Bottom Line: Endoscopy showed a 1-cm sized is polyp with hyperemic change originating from the cardia adjacent to the esophagogastric junction, the biopsy of which suggested a diagnosis of squamous papilloma.Endoscopic mucosal resection was performed to obtain a definite diagnosis and the polyp was completely removed.The histological result was compatible with squamous papilloma, and its surrounding tissues showed foveolar epithelium, which suggested a stomach origin.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Medical Research Institute, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

ABSTRACT
A papilloma is a benign epithelial lesion characterized by finger-like projections of tissue lined by an overgrowth of squamous cells and a core of connective tissue. We report a case of squamous papilloma on the cardia in a 52-year-old asymptomatic female. Endoscopy showed a 1-cm sized is polyp with hyperemic change originating from the cardia adjacent to the esophagogastric junction, the biopsy of which suggested a diagnosis of squamous papilloma. Endoscopic mucosal resection was performed to obtain a definite diagnosis and the polyp was completely removed. The histological result was compatible with squamous papilloma, and its surrounding tissues showed foveolar epithelium, which suggested a stomach origin. This is the first report of endoscopic resection of a gastric squamous papilloma. Squamous papilloma should be considered in the differential diagnosis of a gastric polyp, especially one in the cardia. As the prognostic value of a squamous papilloma is not well known, we recommend endoscopic resection to treat a gastric squamous papilloma, when possible.

No MeSH data available.


Related in: MedlinePlus

Macroscopic findings of the resected specimen reveals a 1-cm sized polyp with a characteristic verrucous appearance.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4260108&req=5

Figure 2: Macroscopic findings of the resected specimen reveals a 1-cm sized polyp with a characteristic verrucous appearance.

Mentions: An asymptomatic 52-year-old woman was referred to Pusan National University Yangsan Hospital for evaluation of a polyp detected by endoscopy. She had neither a history of operations nor a medical history of conditions such as diabetes, hypertension, hepatitis, or tuberculosis. She drank alcohol in moderation and did not smoke. An initial endoscopic evaluation for a routine health check up at the local hospital revealed a 1-cm sized Is polyp with hyperemic change in the cardia. A second endoscopy was performed in our institution and showed a 1-cm sized polyp originating from the cardia just below the esophagogastric junction, with a whitish granular surface in the front view (Fig. 1A) and a hyperemic surface in the retroflex view (Fig. 1B). Biopsy samples taken from the lesion revealed squamous epithelium-lined, inflamed mucosa showing papillary growth, which is suggestive of squamous papilloma. She subsequently underwent an endoscopic mucosal resection and no procedure-related complications occurred. The specimen had a characteristic verrucous appearance (Fig. 2). Histological analysis of the resected specimen showed proliferation of the squamous epithelium without atypia, accompanied by a papillary projection with a fibrovascular core, which is consistent with papilloma. Surrounding tissues containing foveolar epithelium revealed that the polyp originated in the stomach, thus confirming the diagnosis of gastric squamous papilloma (Fig. 3). HPV DNA was Papillomanot detected in the resection specimen. Six months later, endoscopy showed complete healing of the mucosa without residual papilloma or recurrence (Fig. 4).


Gastric squamous papilloma in a 52-year-old female patient.

Jang HH, Kim HW, Kim SJ, Choi CW, Park SB, Song BJ, Shin DH, Kang DH - Clin Endosc (2014)

Macroscopic findings of the resected specimen reveals a 1-cm sized polyp with a characteristic verrucous appearance.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260108&req=5

Figure 2: Macroscopic findings of the resected specimen reveals a 1-cm sized polyp with a characteristic verrucous appearance.
Mentions: An asymptomatic 52-year-old woman was referred to Pusan National University Yangsan Hospital for evaluation of a polyp detected by endoscopy. She had neither a history of operations nor a medical history of conditions such as diabetes, hypertension, hepatitis, or tuberculosis. She drank alcohol in moderation and did not smoke. An initial endoscopic evaluation for a routine health check up at the local hospital revealed a 1-cm sized Is polyp with hyperemic change in the cardia. A second endoscopy was performed in our institution and showed a 1-cm sized polyp originating from the cardia just below the esophagogastric junction, with a whitish granular surface in the front view (Fig. 1A) and a hyperemic surface in the retroflex view (Fig. 1B). Biopsy samples taken from the lesion revealed squamous epithelium-lined, inflamed mucosa showing papillary growth, which is suggestive of squamous papilloma. She subsequently underwent an endoscopic mucosal resection and no procedure-related complications occurred. The specimen had a characteristic verrucous appearance (Fig. 2). Histological analysis of the resected specimen showed proliferation of the squamous epithelium without atypia, accompanied by a papillary projection with a fibrovascular core, which is consistent with papilloma. Surrounding tissues containing foveolar epithelium revealed that the polyp originated in the stomach, thus confirming the diagnosis of gastric squamous papilloma (Fig. 3). HPV DNA was Papillomanot detected in the resection specimen. Six months later, endoscopy showed complete healing of the mucosa without residual papilloma or recurrence (Fig. 4).

Bottom Line: Endoscopy showed a 1-cm sized is polyp with hyperemic change originating from the cardia adjacent to the esophagogastric junction, the biopsy of which suggested a diagnosis of squamous papilloma.Endoscopic mucosal resection was performed to obtain a definite diagnosis and the polyp was completely removed.The histological result was compatible with squamous papilloma, and its surrounding tissues showed foveolar epithelium, which suggested a stomach origin.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Medical Research Institute, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

ABSTRACT
A papilloma is a benign epithelial lesion characterized by finger-like projections of tissue lined by an overgrowth of squamous cells and a core of connective tissue. We report a case of squamous papilloma on the cardia in a 52-year-old asymptomatic female. Endoscopy showed a 1-cm sized is polyp with hyperemic change originating from the cardia adjacent to the esophagogastric junction, the biopsy of which suggested a diagnosis of squamous papilloma. Endoscopic mucosal resection was performed to obtain a definite diagnosis and the polyp was completely removed. The histological result was compatible with squamous papilloma, and its surrounding tissues showed foveolar epithelium, which suggested a stomach origin. This is the first report of endoscopic resection of a gastric squamous papilloma. Squamous papilloma should be considered in the differential diagnosis of a gastric polyp, especially one in the cardia. As the prognostic value of a squamous papilloma is not well known, we recommend endoscopic resection to treat a gastric squamous papilloma, when possible.

No MeSH data available.


Related in: MedlinePlus