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Successful treatment of a gastric plasmacytoma using a combination of endoscopic submucosal dissection and oral thalidomide.

Park SY, Moon HS, Seong JK, Jeong HY, Yoon BY, Hwang SW, Song KS - Clin Endosc (2014)

Bottom Line: He had no specific medical history and unremarkable laboratory results.Follow-up gastroendoscopy was performed three times during a 2-year period and showed nonspecific ESD scarring.The patient's condition was found to be stable.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

ABSTRACT
We report a rare case of a gastric plasmacytoma treated with endoscopic resection and oral thalidomide therapy. A 70-year-old man was admitted to our hospital with indigestion. He had no specific medical history and unremarkable laboratory results. Gastroendoscopic findings revealed a focal, erythematous, flat elevated lesion in the anterior wall of the stomach antrum. A biopsy revealed atypical lymphocytes. Endoscopic submucosal dissection (ESD) with an insulation-tipped knife was performed 45 days after diagnosis. Radiological and hematological evaluations, including a bone marrow biopsy, were performed and showed no involvement of other organs. The patient was diagnosed with extramedullary gastric plasmacytoma. Follow-up gastroendoscopy was performed three times during a 2-year period and showed nonspecific ESD scarring. The patient's condition was found to be stable.

No MeSH data available.


Related in: MedlinePlus

(A) Gastroendoscopic findings showed nonspecific endoscopic submucosal dissection (ESD) scarring 1 year after ESD. (B) Gastroendoscopic findings showed no interval change in ESD scarring 2 years after ESD.
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Figure 4: (A) Gastroendoscopic findings showed nonspecific endoscopic submucosal dissection (ESD) scarring 1 year after ESD. (B) Gastroendoscopic findings showed no interval change in ESD scarring 2 years after ESD.

Mentions: We finally diagnosed the patient with gastric EMP. Because EMPs are systemic, the patient was treated with additional oral thalidomide and dexamethasone. Later, we performed three endoscopic follow-up exams during a 2-year period and confirmed nonspecific ESD scarring. We found the patient's condition to be stable (Fig. 4).


Successful treatment of a gastric plasmacytoma using a combination of endoscopic submucosal dissection and oral thalidomide.

Park SY, Moon HS, Seong JK, Jeong HY, Yoon BY, Hwang SW, Song KS - Clin Endosc (2014)

(A) Gastroendoscopic findings showed nonspecific endoscopic submucosal dissection (ESD) scarring 1 year after ESD. (B) Gastroendoscopic findings showed no interval change in ESD scarring 2 years after ESD.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4260106&req=5

Figure 4: (A) Gastroendoscopic findings showed nonspecific endoscopic submucosal dissection (ESD) scarring 1 year after ESD. (B) Gastroendoscopic findings showed no interval change in ESD scarring 2 years after ESD.
Mentions: We finally diagnosed the patient with gastric EMP. Because EMPs are systemic, the patient was treated with additional oral thalidomide and dexamethasone. Later, we performed three endoscopic follow-up exams during a 2-year period and confirmed nonspecific ESD scarring. We found the patient's condition to be stable (Fig. 4).

Bottom Line: He had no specific medical history and unremarkable laboratory results.Follow-up gastroendoscopy was performed three times during a 2-year period and showed nonspecific ESD scarring.The patient's condition was found to be stable.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

ABSTRACT
We report a rare case of a gastric plasmacytoma treated with endoscopic resection and oral thalidomide therapy. A 70-year-old man was admitted to our hospital with indigestion. He had no specific medical history and unremarkable laboratory results. Gastroendoscopic findings revealed a focal, erythematous, flat elevated lesion in the anterior wall of the stomach antrum. A biopsy revealed atypical lymphocytes. Endoscopic submucosal dissection (ESD) with an insulation-tipped knife was performed 45 days after diagnosis. Radiological and hematological evaluations, including a bone marrow biopsy, were performed and showed no involvement of other organs. The patient was diagnosed with extramedullary gastric plasmacytoma. Follow-up gastroendoscopy was performed three times during a 2-year period and showed nonspecific ESD scarring. The patient's condition was found to be stable.

No MeSH data available.


Related in: MedlinePlus