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COPD: adherence to therapy.

Sanduzzi A, Balbo P, Candoli P, Catapano GA, Contini P, Mattei A, Puglisi G, Santoiemma L, Stanziola AA - Multidiscip Respir Med (2014)

Bottom Line: Depending on the answers, patients who do not comply with their pharmacological treatment may be classified as belonging to 6 phenotypes.Once the risk of non-compliance is identified, four possible types of measures can be taken: prescription-related, educational, behavioral and complex combined measures (combination of two or more actions).Each medication is able to foster good compliance with the therapy, and consequently to maximize the efficacy, by virtue of its specific inhaler and its own active ingredient.

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory Diseases, Monaldi Hospital, University Federico II, Naples, Italy.

ABSTRACT
Adherence to medical therapies is a growing issue, so much so that the World Health Organization defined it as "a new pharmacological problem". The main factors affecting compliance are: frequency of administration, rapid onset of action, role of device. The most severe consequence of non-adherence is the increased risk of poor clinical outcome, associated with worsening of the quality of life and increase in health-care expenditure. It appears crucial to identify those COPD patients who are "poorly or not at all compliant with their treatment". In order to evaluate adherence to the medical therapy, several methods were proposed, the most effective of which turned out to be self-reports, i.e. simple, brief questionnaires (e.g. Morisky test). To increase the likelihood of quickly identifying non-compliant patients, it may be useful to administer a simple questionnaire to naïve subjects (for example, in the waiting room before an examination) including six specific items allowing to identify the patient's key characteristics. Depending on the answers, patients who do not comply with their pharmacological treatment may be classified as belonging to 6 phenotypes. For patients who are already under treatment it might be useful to administer another short questionnaire during follow up examination. Once the risk of non-compliance is identified, four possible types of measures can be taken: prescription-related, educational, behavioral and complex combined measures (combination of two or more actions). Therefore, while it is clear that adherence in COPD is a critical issue, it is also obvious that raising awareness on the disease and improving cooperation among specialists, general practitioners, health-care professionals, and patients is the starting point at which this evolution should immediately begin. Each medication is able to foster good compliance with the therapy, and consequently to maximize the efficacy, by virtue of its specific inhaler and its own active ingredient.

No MeSH data available.


Related in: MedlinePlus

Percentage of days under treatment as a function of the number of daily administrations in patients with chronic obstructive pulmonary disease. Mod. from [19].
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Fig2: Percentage of days under treatment as a function of the number of daily administrations in patients with chronic obstructive pulmonary disease. Mod. from [19].

Mentions: One of the key factors for achieving good compliance is the number of daily administrations. It is actually well known that the higher is the number of administrations, the lower the adherence to the medical therapy. The percentage of compliant COPD patients drops from 43% with a once daily medication to 23% with a therapy requiring 4 administrations per day (Figure 2) [19].


COPD: adherence to therapy.

Sanduzzi A, Balbo P, Candoli P, Catapano GA, Contini P, Mattei A, Puglisi G, Santoiemma L, Stanziola AA - Multidiscip Respir Med (2014)

Percentage of days under treatment as a function of the number of daily administrations in patients with chronic obstructive pulmonary disease. Mod. from [19].
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4256899&req=5

Fig2: Percentage of days under treatment as a function of the number of daily administrations in patients with chronic obstructive pulmonary disease. Mod. from [19].
Mentions: One of the key factors for achieving good compliance is the number of daily administrations. It is actually well known that the higher is the number of administrations, the lower the adherence to the medical therapy. The percentage of compliant COPD patients drops from 43% with a once daily medication to 23% with a therapy requiring 4 administrations per day (Figure 2) [19].

Bottom Line: Depending on the answers, patients who do not comply with their pharmacological treatment may be classified as belonging to 6 phenotypes.Once the risk of non-compliance is identified, four possible types of measures can be taken: prescription-related, educational, behavioral and complex combined measures (combination of two or more actions).Each medication is able to foster good compliance with the therapy, and consequently to maximize the efficacy, by virtue of its specific inhaler and its own active ingredient.

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory Diseases, Monaldi Hospital, University Federico II, Naples, Italy.

ABSTRACT
Adherence to medical therapies is a growing issue, so much so that the World Health Organization defined it as "a new pharmacological problem". The main factors affecting compliance are: frequency of administration, rapid onset of action, role of device. The most severe consequence of non-adherence is the increased risk of poor clinical outcome, associated with worsening of the quality of life and increase in health-care expenditure. It appears crucial to identify those COPD patients who are "poorly or not at all compliant with their treatment". In order to evaluate adherence to the medical therapy, several methods were proposed, the most effective of which turned out to be self-reports, i.e. simple, brief questionnaires (e.g. Morisky test). To increase the likelihood of quickly identifying non-compliant patients, it may be useful to administer a simple questionnaire to naïve subjects (for example, in the waiting room before an examination) including six specific items allowing to identify the patient's key characteristics. Depending on the answers, patients who do not comply with their pharmacological treatment may be classified as belonging to 6 phenotypes. For patients who are already under treatment it might be useful to administer another short questionnaire during follow up examination. Once the risk of non-compliance is identified, four possible types of measures can be taken: prescription-related, educational, behavioral and complex combined measures (combination of two or more actions). Therefore, while it is clear that adherence in COPD is a critical issue, it is also obvious that raising awareness on the disease and improving cooperation among specialists, general practitioners, health-care professionals, and patients is the starting point at which this evolution should immediately begin. Each medication is able to foster good compliance with the therapy, and consequently to maximize the efficacy, by virtue of its specific inhaler and its own active ingredient.

No MeSH data available.


Related in: MedlinePlus