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Motor fMRI and cortical grey matter volume in adults born very preterm.

Lawrence EJ, Froudist-Walsh S, Neilan R, Nam KW, Giampietro V, McGuire P, Murray RM, Nosarti C - Dev Cogn Neurosci (2014)

Bottom Line: The primary aim of this study was to investigate the functional neuroanatomy of motor planning, initiation and execution in a cohort of young adults (mean age 20 years) who were born very preterm (VPT; <33 weeks of gestation), as these individuals are at increased risk of experiencing neuromotor difficulties compared to controls.The VPT group also displayed decreased grey matter volume in the right superior frontal/premotor cortex and left middle temporal gyri.Grey matter volume in the premotor and middle temporal clusters was significantly negatively correlated with BOLD activation in the cerebellum.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's Health Partners, King's College London, De Crespigny Park, London SE5 8AF, UK. Electronic address: emma.lawrence@kcl.ac.uk.

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Related in: MedlinePlus

Areas of within group brain activation for Control participants. Areas of within control group activation thresholded at voxel-level p < 0.05, cluster-level p < 0.01. Left side of images represents the left hemisphere of the brain.
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fig0005: Areas of within group brain activation for Control participants. Areas of within control group activation thresholded at voxel-level p < 0.05, cluster-level p < 0.01. Left side of images represents the left hemisphere of the brain.


Motor fMRI and cortical grey matter volume in adults born very preterm.

Lawrence EJ, Froudist-Walsh S, Neilan R, Nam KW, Giampietro V, McGuire P, Murray RM, Nosarti C - Dev Cogn Neurosci (2014)

Areas of within group brain activation for Control participants. Areas of within control group activation thresholded at voxel-level p < 0.05, cluster-level p < 0.01. Left side of images represents the left hemisphere of the brain.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4256062&req=5

fig0005: Areas of within group brain activation for Control participants. Areas of within control group activation thresholded at voxel-level p < 0.05, cluster-level p < 0.01. Left side of images represents the left hemisphere of the brain.
Bottom Line: The primary aim of this study was to investigate the functional neuroanatomy of motor planning, initiation and execution in a cohort of young adults (mean age 20 years) who were born very preterm (VPT; <33 weeks of gestation), as these individuals are at increased risk of experiencing neuromotor difficulties compared to controls.The VPT group also displayed decreased grey matter volume in the right superior frontal/premotor cortex and left middle temporal gyri.Grey matter volume in the premotor and middle temporal clusters was significantly negatively correlated with BOLD activation in the cerebellum.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's Health Partners, King's College London, De Crespigny Park, London SE5 8AF, UK. Electronic address: emma.lawrence@kcl.ac.uk.

Show MeSH
Related in: MedlinePlus