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Biomedical research in a Digital Health Framework.

Cano I, Lluch-Ariet M, Gomez-Cabrero D, Maier D, Kalko S, Cascante M, Tegnér J, Miralles F, Herrera D, Roca J, Synergy-COPD consorti - J Transl Med (2014)

Bottom Line: This article describes a Digital Health Framework (DHF), benefitting from the lessons learnt during the three-year life span of the FP7 Synergy-COPD project.Finally, the specifics of the building blocks strategy for deployment of the DHF, as well as the steps toward adoption are analyzed.The proposed architectural solutions and implementation steps constitute a pivotal strategy to foster and enable 4P medicine (Predictive, Preventive, Personalized and Participatory) in practice and should provide a head start to any community and institution currently considering to implement a biomedical research platform.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
This article describes a Digital Health Framework (DHF), benefitting from the lessons learnt during the three-year life span of the FP7 Synergy-COPD project. The DHF aims to embrace the emerging requirements--data and tools--of applying systems medicine into healthcare with a three-tier strategy articulating formal healthcare, informal care and biomedical research. Accordingly, it has been constructed based on three key building blocks, namely, novel integrated care services with the support of information and communication technologies, a personal health folder (PHF) and a biomedical research environment (DHF-research). Details on the functional requirements and necessary components of the DHF-research are extensively presented. Finally, the specifics of the building blocks strategy for deployment of the DHF, as well as the steps toward adoption are analyzed. The proposed architectural solutions and implementation steps constitute a pivotal strategy to foster and enable 4P medicine (Predictive, Preventive, Personalized and Participatory) in practice and should provide a head start to any community and institution currently considering to implement a biomedical research platform.

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The concept of Digital Health Framework covers the different areas wherein information can be obtained and actions are taken: i) informal care, ii) formal care, and, iii) biomedical research. In this scenario, a personal health folder incorporating patient decision support systems (PDSS) might facilitate the incorporation of data coming from informal care into formal healthcare. In addition, biomedical research, referring to all research levels from clinical to basic research, should be shaped to provide user-profiled functionalities such that research professionals with different profiles can make use of clinical and biomedical knowledge from formal healthcare and heterogeneous biomedical research data sources, ultimately leading to the generation of novel rules that should feed in-place clinical decision support systems (CDSS).
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Figure 2: The concept of Digital Health Framework covers the different areas wherein information can be obtained and actions are taken: i) informal care, ii) formal care, and, iii) biomedical research. In this scenario, a personal health folder incorporating patient decision support systems (PDSS) might facilitate the incorporation of data coming from informal care into formal healthcare. In addition, biomedical research, referring to all research levels from clinical to basic research, should be shaped to provide user-profiled functionalities such that research professionals with different profiles can make use of clinical and biomedical knowledge from formal healthcare and heterogeneous biomedical research data sources, ultimately leading to the generation of novel rules that should feed in-place clinical decision support systems (CDSS).

Mentions: The concept of Digital Health Framework (DHF) (Figure 2) emerged from the Synergy-COPD project to foster adoption of predictive medicine. The DHF consists of the articulation of open and modular ICT components supporting organizational interoperability, and appropriate functionalities, among three main areas, namely: i) informal care, ii) formal care, and, iii) biomedical research. Briefly, informal care includes any aspect with impact on health (e.g. life style, environmental and behavioural aspects, etc.) occurring in the community, whereas formal care refers to any interaction with health professionals at different levels of the healthcare system. Biomedical research refers to all research levels from bench to clinical and to public health. In our hands, to materialize such an ambitious vision, a building block approach is considered necessary. Moreover, the progress from the initial proof-of-concept to pilot implementation and to extensive deployment shall be planned following a stepwise strategy.


Biomedical research in a Digital Health Framework.

Cano I, Lluch-Ariet M, Gomez-Cabrero D, Maier D, Kalko S, Cascante M, Tegnér J, Miralles F, Herrera D, Roca J, Synergy-COPD consorti - J Transl Med (2014)

The concept of Digital Health Framework covers the different areas wherein information can be obtained and actions are taken: i) informal care, ii) formal care, and, iii) biomedical research. In this scenario, a personal health folder incorporating patient decision support systems (PDSS) might facilitate the incorporation of data coming from informal care into formal healthcare. In addition, biomedical research, referring to all research levels from clinical to basic research, should be shaped to provide user-profiled functionalities such that research professionals with different profiles can make use of clinical and biomedical knowledge from formal healthcare and heterogeneous biomedical research data sources, ultimately leading to the generation of novel rules that should feed in-place clinical decision support systems (CDSS).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4255881&req=5

Figure 2: The concept of Digital Health Framework covers the different areas wherein information can be obtained and actions are taken: i) informal care, ii) formal care, and, iii) biomedical research. In this scenario, a personal health folder incorporating patient decision support systems (PDSS) might facilitate the incorporation of data coming from informal care into formal healthcare. In addition, biomedical research, referring to all research levels from clinical to basic research, should be shaped to provide user-profiled functionalities such that research professionals with different profiles can make use of clinical and biomedical knowledge from formal healthcare and heterogeneous biomedical research data sources, ultimately leading to the generation of novel rules that should feed in-place clinical decision support systems (CDSS).
Mentions: The concept of Digital Health Framework (DHF) (Figure 2) emerged from the Synergy-COPD project to foster adoption of predictive medicine. The DHF consists of the articulation of open and modular ICT components supporting organizational interoperability, and appropriate functionalities, among three main areas, namely: i) informal care, ii) formal care, and, iii) biomedical research. Briefly, informal care includes any aspect with impact on health (e.g. life style, environmental and behavioural aspects, etc.) occurring in the community, whereas formal care refers to any interaction with health professionals at different levels of the healthcare system. Biomedical research refers to all research levels from bench to clinical and to public health. In our hands, to materialize such an ambitious vision, a building block approach is considered necessary. Moreover, the progress from the initial proof-of-concept to pilot implementation and to extensive deployment shall be planned following a stepwise strategy.

Bottom Line: This article describes a Digital Health Framework (DHF), benefitting from the lessons learnt during the three-year life span of the FP7 Synergy-COPD project.Finally, the specifics of the building blocks strategy for deployment of the DHF, as well as the steps toward adoption are analyzed.The proposed architectural solutions and implementation steps constitute a pivotal strategy to foster and enable 4P medicine (Predictive, Preventive, Personalized and Participatory) in practice and should provide a head start to any community and institution currently considering to implement a biomedical research platform.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
This article describes a Digital Health Framework (DHF), benefitting from the lessons learnt during the three-year life span of the FP7 Synergy-COPD project. The DHF aims to embrace the emerging requirements--data and tools--of applying systems medicine into healthcare with a three-tier strategy articulating formal healthcare, informal care and biomedical research. Accordingly, it has been constructed based on three key building blocks, namely, novel integrated care services with the support of information and communication technologies, a personal health folder (PHF) and a biomedical research environment (DHF-research). Details on the functional requirements and necessary components of the DHF-research are extensively presented. Finally, the specifics of the building blocks strategy for deployment of the DHF, as well as the steps toward adoption are analyzed. The proposed architectural solutions and implementation steps constitute a pivotal strategy to foster and enable 4P medicine (Predictive, Preventive, Personalized and Participatory) in practice and should provide a head start to any community and institution currently considering to implement a biomedical research platform.

Show MeSH