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Resistance exercise increases active MMP and β1-integrin protein expression in skeletal muscle.

Ogasawara R, Nakazato K, Sato K, Boppart MD, Fujita S - Physiol Rep (2014)

Bottom Line: Recent studies indicate that matrix metalloproteinases (MMPs) and critical linkage proteins in the extracellular matrix (ECM) regulate skeletal muscle mass, although the effects of resistance training (RT) on protein expression and activity are unclear.However, β1-integrin protein expression was significantly increased (P < 0.05) with 18B.Our results suggest that resistance exercise activates MMPs during the initial phase of RT but this response is attenuated with continuation of RT.

View Article: PubMed Central - PubMed

Affiliation: Department of Life Sciences, The University of Tokyo, Tokyo, Japan Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan.

No MeSH data available.


Related in: MedlinePlus

Effect of acute and chronic resistance exercise on integrin‐related proteins and dystroglycans. Values are the mean ± SEM. 1B, 1 bout group; 18B, 18 bouts group; C, control muscle; E, exercised muscle. *P <0.05 versus control muscle.
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fig03: Effect of acute and chronic resistance exercise on integrin‐related proteins and dystroglycans. Values are the mean ± SEM. 1B, 1 bout group; 18B, 18 bouts group; C, control muscle; E, exercised muscle. *P <0.05 versus control muscle.

Mentions: No significant change in α‐ and β‐dystroglycan protein expression was observed after acute or chronic muscle contraction (Fig. 3).


Resistance exercise increases active MMP and β1-integrin protein expression in skeletal muscle.

Ogasawara R, Nakazato K, Sato K, Boppart MD, Fujita S - Physiol Rep (2014)

Effect of acute and chronic resistance exercise on integrin‐related proteins and dystroglycans. Values are the mean ± SEM. 1B, 1 bout group; 18B, 18 bouts group; C, control muscle; E, exercised muscle. *P <0.05 versus control muscle.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4255818&req=5

fig03: Effect of acute and chronic resistance exercise on integrin‐related proteins and dystroglycans. Values are the mean ± SEM. 1B, 1 bout group; 18B, 18 bouts group; C, control muscle; E, exercised muscle. *P <0.05 versus control muscle.
Mentions: No significant change in α‐ and β‐dystroglycan protein expression was observed after acute or chronic muscle contraction (Fig. 3).

Bottom Line: Recent studies indicate that matrix metalloproteinases (MMPs) and critical linkage proteins in the extracellular matrix (ECM) regulate skeletal muscle mass, although the effects of resistance training (RT) on protein expression and activity are unclear.However, β1-integrin protein expression was significantly increased (P < 0.05) with 18B.Our results suggest that resistance exercise activates MMPs during the initial phase of RT but this response is attenuated with continuation of RT.

View Article: PubMed Central - PubMed

Affiliation: Department of Life Sciences, The University of Tokyo, Tokyo, Japan Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan.

No MeSH data available.


Related in: MedlinePlus