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Does oxygen delivery explain interindividual variation in forearm critical impulse?

Kellawan JM, Bentley RF, Bravo MF, Moynes JS, Tschakovsky ME - Physiol Rep (2014)

Bottom Line: Both vasodilation (r(2) = 0.64, P < 0.001) and the exercise pressor response (r(2) = 0.33, P < 0.001) independently contributed to interindividual differences in FBF.Furthermore, individual differences in pressor response play an important role in determining differences in O2 delivery in addition to vasodilation.The mechanistic origins of this vasodilatory and pressor response heterogeneity across individuals remain to be determined.

View Article: PubMed Central - PubMed

Affiliation: Department of Kinesiology, School of Education, University of Wisconsin, Madison, Wisconsin.

No MeSH data available.


Related in: MedlinePlus

Change in O2 delivery and contraction impulse during maximal effort exercise. Dotted lines identify stable plateau. Panel A: absolute changes. Dashed line is contraction impulse. Solid line is O2 delivery. Panel B: expressed as % of the change from baseline to steady state for O2 delivery and from the first maximal effort contraction to steady state for contraction impulse. Dashed line and open squares is contraction impulse. Solid line and closed squares is O2 delivery. #Significantly different from steady state within a variable. *Significantly different from O2 delivery at a given time point. All P < 0.05.
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fig03: Change in O2 delivery and contraction impulse during maximal effort exercise. Dotted lines identify stable plateau. Panel A: absolute changes. Dashed line is contraction impulse. Solid line is O2 delivery. Panel B: expressed as % of the change from baseline to steady state for O2 delivery and from the first maximal effort contraction to steady state for contraction impulse. Dashed line and open squares is contraction impulse. Solid line and closed squares is O2 delivery. #Significantly different from steady state within a variable. *Significantly different from O2 delivery at a given time point. All P < 0.05.

Mentions: Figure 3 illustrates the time course of changes in O2 delivery and contraction impulse over the course of a 10 min, maximal effort handgrip exercise test. O2 delivery increased to a stable plateau, whereas maximal effort contraction impulse declined to a stable plateau (Fig. 3A). The magnitude of change from onset to plateau is expressed as % of change from onset to plateau in Fig. 3B in order to facilitate comparison of the time to plateau in O2 delivery versus contraction impulse. The increase in O2 delivery to stable plateau is no longer statistically significantly different from stable plateau by 90 sec (P = 0.48), whereas the contraction impulse remains statistically significantly below steady state and lower than the change in O2 delivery up to 210 sec (P = 0.03 and P = 0.02, respectively, at 210 sec), confirming that O2 delivery stabilizes well before contraction impulse during this type of exercise.


Does oxygen delivery explain interindividual variation in forearm critical impulse?

Kellawan JM, Bentley RF, Bravo MF, Moynes JS, Tschakovsky ME - Physiol Rep (2014)

Change in O2 delivery and contraction impulse during maximal effort exercise. Dotted lines identify stable plateau. Panel A: absolute changes. Dashed line is contraction impulse. Solid line is O2 delivery. Panel B: expressed as % of the change from baseline to steady state for O2 delivery and from the first maximal effort contraction to steady state for contraction impulse. Dashed line and open squares is contraction impulse. Solid line and closed squares is O2 delivery. #Significantly different from steady state within a variable. *Significantly different from O2 delivery at a given time point. All P < 0.05.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4255810&req=5

fig03: Change in O2 delivery and contraction impulse during maximal effort exercise. Dotted lines identify stable plateau. Panel A: absolute changes. Dashed line is contraction impulse. Solid line is O2 delivery. Panel B: expressed as % of the change from baseline to steady state for O2 delivery and from the first maximal effort contraction to steady state for contraction impulse. Dashed line and open squares is contraction impulse. Solid line and closed squares is O2 delivery. #Significantly different from steady state within a variable. *Significantly different from O2 delivery at a given time point. All P < 0.05.
Mentions: Figure 3 illustrates the time course of changes in O2 delivery and contraction impulse over the course of a 10 min, maximal effort handgrip exercise test. O2 delivery increased to a stable plateau, whereas maximal effort contraction impulse declined to a stable plateau (Fig. 3A). The magnitude of change from onset to plateau is expressed as % of change from onset to plateau in Fig. 3B in order to facilitate comparison of the time to plateau in O2 delivery versus contraction impulse. The increase in O2 delivery to stable plateau is no longer statistically significantly different from stable plateau by 90 sec (P = 0.48), whereas the contraction impulse remains statistically significantly below steady state and lower than the change in O2 delivery up to 210 sec (P = 0.03 and P = 0.02, respectively, at 210 sec), confirming that O2 delivery stabilizes well before contraction impulse during this type of exercise.

Bottom Line: Both vasodilation (r(2) = 0.64, P < 0.001) and the exercise pressor response (r(2) = 0.33, P < 0.001) independently contributed to interindividual differences in FBF.Furthermore, individual differences in pressor response play an important role in determining differences in O2 delivery in addition to vasodilation.The mechanistic origins of this vasodilatory and pressor response heterogeneity across individuals remain to be determined.

View Article: PubMed Central - PubMed

Affiliation: Department of Kinesiology, School of Education, University of Wisconsin, Madison, Wisconsin.

No MeSH data available.


Related in: MedlinePlus