Lifecourse relationship between maternal smoking during pregnancy, birth weight, contemporaneous anthropometric measurements and bone mass at 18years old. The 1993 Pelotas Birth Cohort.
Bottom Line: Maternal smoking during pregnancy is associated with short-term and also long-term harmful effects on offspring.Each additional cigarette smoked during pregnancy was associated with a lower BMC by -4.20 g in males (95% CI -8.37; -0.05), but not in females [-2.22 g (95% CI -5.49; 1.04)]; weaker inverse associations were observed for BMD.A 1 kg higher birth weight was associated with a higher BMC by around 144 g in males and by around 186 g in females, and also with a higher BMD by around 0.019 g/cm(2) in males and by around 0.018 g/cm(2) in females, respectively.
Affiliation: Postgraduate Program in Epidemiology, Federal University of Pelotas, Rio Grande do Sul, Brazil. Electronic address: firstname.lastname@example.org.Show MeSH
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Affiliation: Postgraduate Program in Epidemiology, Federal University of Pelotas, Rio Grande do Sul, Brazil. Electronic address: email@example.com.