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Nodular Erythema Elevatum Diutinum Mimicking Kaposi's Sarcoma in a Human Immunodeficiency Virus Infected Patient.

Rao GR, Joshi R, Phaneendra Prasad AK, Amareswar A, Sandhya S, Sridevi M - Indian J Dermatol (2014)

Bottom Line: Erythema elevatum diutinum (EED) has been emerging as a specific Human Immunodeficiency Virus (HIV) associated dermatosis in recent times.We describe a case of EED simulating Kaposi's sarcoma in a 52-year-old HIV infected female patient with no previous opportunistic infections and CD4+ count of 164/mm(3).Therapy with oral dapsone (100 mg/day) for two weeks resulted in resolution of some lesions.

View Article: PubMed Central - PubMed

Affiliation: Department of DVL, GSL Medical College, Rajahmundry, Andhra Pradesh, India.

ABSTRACT
Erythema elevatum diutinum (EED) has been emerging as a specific Human Immunodeficiency Virus (HIV) associated dermatosis in recent times. It is an extremely rare chronic disease of unknown origin and part of the spectrum of leukocytoclastic vasculitis. We describe a case of EED simulating Kaposi's sarcoma in a 52-year-old HIV infected female patient with no previous opportunistic infections and CD4+ count of 164/mm(3). Therapy with oral dapsone (100 mg/day) for two weeks resulted in resolution of some lesions.

No MeSH data available.


Related in: MedlinePlus

Multiple, dusky red, large nodules and plaques on the legs
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Figure 1: Multiple, dusky red, large nodules and plaques on the legs

Mentions: A 52-year-old married HIV infected woman, who had been on ART for the last seven years (Zidovudine + Lamivudine + Nevirapine), was referred for evaluation of skin lesions that had appeared nine months ago. There was no history of any opportunistic infection before the onset of skin nodules. Except arthralgia and mild constitutional symptoms, her general condition was fairly good and all her vitals were within normal limits. On examination, there were multiple, dusky red, large nodules and plaques over the feet, ankles, soles, shins, knees, and elbows. Majority of the lesions were non tender and symmetrically distributed [Figures 1 and 2]. Few nodules over the soles were painful and ruptured with sero-sanguinous discharge. Some nodules over the shins healed with hyperpigmented macules. Inguinal lymph nodes on both sides were palpable and firm in consistency. There were no lesions elsewhere over the body and no mucosal lesions were present. Systemic examination disclosed no abnormalities. On ophthalmologic examination, there were no lesions in the eyes. Clinically, Kaposi's sarcoma or bacillary angiomatosis was suspected and the case was evaluated.


Nodular Erythema Elevatum Diutinum Mimicking Kaposi's Sarcoma in a Human Immunodeficiency Virus Infected Patient.

Rao GR, Joshi R, Phaneendra Prasad AK, Amareswar A, Sandhya S, Sridevi M - Indian J Dermatol (2014)

Multiple, dusky red, large nodules and plaques on the legs
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4248498&req=5

Figure 1: Multiple, dusky red, large nodules and plaques on the legs
Mentions: A 52-year-old married HIV infected woman, who had been on ART for the last seven years (Zidovudine + Lamivudine + Nevirapine), was referred for evaluation of skin lesions that had appeared nine months ago. There was no history of any opportunistic infection before the onset of skin nodules. Except arthralgia and mild constitutional symptoms, her general condition was fairly good and all her vitals were within normal limits. On examination, there were multiple, dusky red, large nodules and plaques over the feet, ankles, soles, shins, knees, and elbows. Majority of the lesions were non tender and symmetrically distributed [Figures 1 and 2]. Few nodules over the soles were painful and ruptured with sero-sanguinous discharge. Some nodules over the shins healed with hyperpigmented macules. Inguinal lymph nodes on both sides were palpable and firm in consistency. There were no lesions elsewhere over the body and no mucosal lesions were present. Systemic examination disclosed no abnormalities. On ophthalmologic examination, there were no lesions in the eyes. Clinically, Kaposi's sarcoma or bacillary angiomatosis was suspected and the case was evaluated.

Bottom Line: Erythema elevatum diutinum (EED) has been emerging as a specific Human Immunodeficiency Virus (HIV) associated dermatosis in recent times.We describe a case of EED simulating Kaposi's sarcoma in a 52-year-old HIV infected female patient with no previous opportunistic infections and CD4+ count of 164/mm(3).Therapy with oral dapsone (100 mg/day) for two weeks resulted in resolution of some lesions.

View Article: PubMed Central - PubMed

Affiliation: Department of DVL, GSL Medical College, Rajahmundry, Andhra Pradesh, India.

ABSTRACT
Erythema elevatum diutinum (EED) has been emerging as a specific Human Immunodeficiency Virus (HIV) associated dermatosis in recent times. It is an extremely rare chronic disease of unknown origin and part of the spectrum of leukocytoclastic vasculitis. We describe a case of EED simulating Kaposi's sarcoma in a 52-year-old HIV infected female patient with no previous opportunistic infections and CD4+ count of 164/mm(3). Therapy with oral dapsone (100 mg/day) for two weeks resulted in resolution of some lesions.

No MeSH data available.


Related in: MedlinePlus