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Successful flexible bronchoscopic management of dynamic central airway obstruction by a large tracheal carcinoid tumor.

Hadda V, Madan K, Mohan A, Kalai U, Guleria R - Case Rep Pulmonol (2014)

Bottom Line: Typical carcinoid of the trachea presenting as an endoluminal polypoidal mass is a rare occurrence.Flexible bronchoscopy demonstrated a large pedunculated growth arising from the lower end of the trachea near carina which was flopping in and out of the main tracheal lumen and the proximal right bronchus leading to dynamic airway obstruction.The patient had immediate relief of airway obstruction and histopathological examination of the polyp demonstrated features of typical carcinoid (WHO Grade I neuroendocrine tumor).

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi 110029, India.

ABSTRACT
Typical carcinoid of the trachea presenting as an endoluminal polypoidal mass is a rare occurrence. Herein, we report a case of a 34-year-old female patient who presented with features of central airway obstruction. Flexible bronchoscopy demonstrated a large pedunculated growth arising from the lower end of the trachea near carina which was flopping in and out of the main tracheal lumen and the proximal right bronchus leading to dynamic airway obstruction. Successful electrosurgical excision (using a snare loop) of the polypoidal growth was performed using the flexible bronchoscope itself. The patient had immediate relief of airway obstruction and histopathological examination of the polyp demonstrated features of typical carcinoid (WHO Grade I neuroendocrine tumor).

No MeSH data available.


Related in: MedlinePlus

Histopathology of the ablated tumor showing features of carcinoid. Tumor cells are arranged in nests with rich vascular stroma (a). They show salt and pepper type of nuclear chromatin (b). Immunohistochemistry shows positivity for synaptophysin (c) with increased proliferating (KI 67 labelling) index (d).
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fig3: Histopathology of the ablated tumor showing features of carcinoid. Tumor cells are arranged in nests with rich vascular stroma (a). They show salt and pepper type of nuclear chromatin (b). Immunohistochemistry shows positivity for synaptophysin (c) with increased proliferating (KI 67 labelling) index (d).

Mentions: The histopathology of the tracheal growth was suggestive of carcinoid (Figure 3). A DOTANOC Positron Emission Tomographic CT scan was performed later which demonstrated no areas of abnormal tracer uptake. Patient is under regular follow-up and follow-up bronchoscopic examination has been normal.


Successful flexible bronchoscopic management of dynamic central airway obstruction by a large tracheal carcinoid tumor.

Hadda V, Madan K, Mohan A, Kalai U, Guleria R - Case Rep Pulmonol (2014)

Histopathology of the ablated tumor showing features of carcinoid. Tumor cells are arranged in nests with rich vascular stroma (a). They show salt and pepper type of nuclear chromatin (b). Immunohistochemistry shows positivity for synaptophysin (c) with increased proliferating (KI 67 labelling) index (d).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4247927&req=5

fig3: Histopathology of the ablated tumor showing features of carcinoid. Tumor cells are arranged in nests with rich vascular stroma (a). They show salt and pepper type of nuclear chromatin (b). Immunohistochemistry shows positivity for synaptophysin (c) with increased proliferating (KI 67 labelling) index (d).
Mentions: The histopathology of the tracheal growth was suggestive of carcinoid (Figure 3). A DOTANOC Positron Emission Tomographic CT scan was performed later which demonstrated no areas of abnormal tracer uptake. Patient is under regular follow-up and follow-up bronchoscopic examination has been normal.

Bottom Line: Typical carcinoid of the trachea presenting as an endoluminal polypoidal mass is a rare occurrence.Flexible bronchoscopy demonstrated a large pedunculated growth arising from the lower end of the trachea near carina which was flopping in and out of the main tracheal lumen and the proximal right bronchus leading to dynamic airway obstruction.The patient had immediate relief of airway obstruction and histopathological examination of the polyp demonstrated features of typical carcinoid (WHO Grade I neuroendocrine tumor).

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi 110029, India.

ABSTRACT
Typical carcinoid of the trachea presenting as an endoluminal polypoidal mass is a rare occurrence. Herein, we report a case of a 34-year-old female patient who presented with features of central airway obstruction. Flexible bronchoscopy demonstrated a large pedunculated growth arising from the lower end of the trachea near carina which was flopping in and out of the main tracheal lumen and the proximal right bronchus leading to dynamic airway obstruction. Successful electrosurgical excision (using a snare loop) of the polypoidal growth was performed using the flexible bronchoscope itself. The patient had immediate relief of airway obstruction and histopathological examination of the polyp demonstrated features of typical carcinoid (WHO Grade I neuroendocrine tumor).

No MeSH data available.


Related in: MedlinePlus