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Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy.

Hammodi A, Al-Azem MA, Hanafy A, Nakkar T - Case Rep Crit Care (2014)

Bottom Line: Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients.Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE.We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.

View Article: PubMed Central - PubMed

Affiliation: King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi Arabia.

ABSTRACT
Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE. One of the peculiar characteristics of tumor cells is their ability to reach the circulation and behave as blood clot-not a metastasis-occluding the pulmonary circulation. We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.

No MeSH data available.


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Mentions: Afterward, high resolution CT of the chest (Figure 2) was done and showed bilateral diffuse ground glass density of the lungs, with centrilobular nodular densities and mild reticulations. However, no volume loss, honeycombing formation, or pleural effusion was seen. Similarly, no significant axillary, hilar, or mediastinal lymph nodes were seen either. Small pericardial effusion was noted. CT Chest PE Study excluded any evidence of pulmonary embolism.


Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy.

Hammodi A, Al-Azem MA, Hanafy A, Nakkar T - Case Rep Crit Care (2014)

© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4247920&req=5

Mentions: Afterward, high resolution CT of the chest (Figure 2) was done and showed bilateral diffuse ground glass density of the lungs, with centrilobular nodular densities and mild reticulations. However, no volume loss, honeycombing formation, or pleural effusion was seen. Similarly, no significant axillary, hilar, or mediastinal lymph nodes were seen either. Small pericardial effusion was noted. CT Chest PE Study excluded any evidence of pulmonary embolism.

Bottom Line: Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients.Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE.We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.

View Article: PubMed Central - PubMed

Affiliation: King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi Arabia.

ABSTRACT
Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE. One of the peculiar characteristics of tumor cells is their ability to reach the circulation and behave as blood clot-not a metastasis-occluding the pulmonary circulation. We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.

No MeSH data available.


Related in: MedlinePlus