Distribution of anticoagulant rodenticide resistance in Rattus norvegicus in the Netherlands according to Vkorc1 mutations.
Bottom Line: Here, the authors present the results of a survey in the Netherlands where tissue samples and droppings were tested using a newly developed TaqMan PCR test for genotypic variation at codon 139 in the Vkorc1 gene associated with anticoagulant rodenticide resistance.In addition, indications of a clear genetic substructure in the Netherlands were found.As rodenticides should keep their efficacy because they are a last resort in rodent management, more studies are urgently needed that link specific genetic mutations to the efficacy of active substances.
Affiliation: Wageningen UR Livestock Research, Lelystad, The Netherlands.Show MeSH
Related in: MedlinePlus
Affiliation: Wageningen UR Livestock Research, Lelystad, The Netherlands.