Systematic review of severe fever with thrombocytopenia syndrome: virology, epidemiology, and clinical characteristics.
Bottom Line: A wide range of domesticated animals, including sheep, goats, cattle, pigs, dogs, and chickens have been proven seropositive for SFTSV.Ticks, especially Haemaphysalis longicornis, are suspected to be the potential vector, which have a broad animal host range in the world.More studies are needed to elucidate the vector-animal-human ecological cycle, the pathogenic mechanisms in high level animal models and vaccine development.
Affiliation: Department of Infectious Diseases, Zhejiang Provincial Centre for Disease Control and Prevention, Hangzhou, Zhejiang Province, China.Show MeSH
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Mentions: Review of clinical symptoms and signs reported in previous studies 1,2,36,55 for surviving and fatal cases, respectively, indicated fever (78.28%, 100.00%), anorexia (63.35%, 64.00%), fatigue (62.44%, 55.00%), body sores [52.71%, no data available (NA)], nausea (52.49%, 45.00%), vomiting (45.93%, 36.00%), diarrhea (45.70%, 27.00%), myalgia (44.12%, 18.00%), chills (41.63%, NA), abdominal pain (40.05%, 36.00%), coarse breathing sounds (38.46%, NA), dizziness (37.10%, NA), headache (36.43%, NA), enlargement of lymph nodes (34.16%, 18.00%), cough (28.73%, 18.00%), confusion (22.00%, 36.00%), sputum production (20.14%, NA), arthralgia (19.91%, NA), throat congestion (12.00%, 18.00%), conjunctive congestion (10.00%, NA), apathy (9.00%, 9.00%), petechiae (7.00%, 27.00%), coma (6.00%, 27.00%), slurred speech (6.00%, 9.00%), and skin rash (4.30%, NA) (Figure 8).
Affiliation: Department of Infectious Diseases, Zhejiang Provincial Centre for Disease Control and Prevention, Hangzhou, Zhejiang Province, China.