Effects of millimeter wave irradiation and equivalent thermal heating on the activity of individual neurons in the leech ganglion.
Bottom Line: Many of today's radiofrequency-emitting devices in telecommunication, telemedicine, transportation safety, and security/military applications use the millimeter wave (MMW) band (30-300 GHz).For comparison, the recognized U.S. safe exposure limit is 1 mW/cm(2) for 6 min.During the exposure to MMWs and gradual bath heating at a rate of 0.04°C/s (2.4°C/min), the ganglionic neurons exhibited similar dose-dependent hyperpolarization of the plasma membrane and decrease in the action potential amplitude.
Affiliation: Division of Engineering and Applied Science, California Institute of Technology, Pasadena, California; Neural Engineering Program, Huntington Medical Research Institutes, Pasadena, California; and.Show MeSH
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Mentions: The MMW effects at multiple incident power densities were analyzed using the SPSS general linear model (SPSS, Chicago, IL), followed by Dunnet one-sided post hoc t-tests for the postirradiation data compared with preirradiation controls. The bath heating effects were analyzed using the linear regression model (SPSS), and closeness of the fit is expressed as the adjusted coefficient of determination (R2). Comparison of the MMW and bath heating effects in Fig. 5 was performed using the one-tailed t-test. The significance levels of 0.05, 0.01, and 0.001 were used. The results are reported as means ± SE (except for Fig. 2, where values are means ± SD).
Affiliation: Division of Engineering and Applied Science, California Institute of Technology, Pasadena, California; Neural Engineering Program, Huntington Medical Research Institutes, Pasadena, California; and.