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Genome sequence of Candidatus Riesia pediculischaeffi, endosymbiont of chimpanzee lice, and genomic comparison of recently acquired endosymbionts from human and chimpanzee lice.

Boyd BM, Allen JM, de Crécy-Lagard V, Reed DL - G3 (Bethesda) (2014)

Bottom Line: Although gene loss was detected, it was not significantly greater than in older endosymbionts from aphids and ants.Movement of these genes onto a plasmid may be functionally and evolutionarily significant, potentially increasing production and guarding against the deleterious effects of mutation.Ultimately sequencing additional louse p-endosymbiont genomes will provide a model system for studying genome evolution in obligate host associated bacteria.

View Article: PubMed Central - PubMed

Affiliation: Florida Museum of Natural History, University of Florida, Gainesville, Florida 32611 Genetics and Genomics Graduate Program, University of Florida, Gainesville, Florida 32610 bboyd@ufl.edu.

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Related in: MedlinePlus

Alignment of the 5.2-kb plasmid from the chimpanzee louse p-endosymbiont to the 7.7-kb plasmid from the human louse p-endosymbiont that encodes genes involved pantothenate biosynthesis. Black inner ring is human louse p-endosymbiont plasmid reference sequence, red ring represents the annotation of human louse p-endosymbiont plasmid, and purple outer ring is alignment of query chimpanzee louse p-endosymbiont plasmid sequence. Genes involved in de novo synthesis of pantothenate (panB, panC, and panE) are labeled in red. Image generated using BRIG (Alikhan et al. 2011).
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fig2: Alignment of the 5.2-kb plasmid from the chimpanzee louse p-endosymbiont to the 7.7-kb plasmid from the human louse p-endosymbiont that encodes genes involved pantothenate biosynthesis. Black inner ring is human louse p-endosymbiont plasmid reference sequence, red ring represents the annotation of human louse p-endosymbiont plasmid, and purple outer ring is alignment of query chimpanzee louse p-endosymbiont plasmid sequence. Genes involved in de novo synthesis of pantothenate (panB, panC, and panE) are labeled in red. Image generated using BRIG (Alikhan et al. 2011).

Mentions: This genome was similar to the human louse p-endosymbiont (Ca. Riesia pediculicola) genome in size and composition (Table 2). Overall gene order and genomic synteny have been maintained between these species, with the exception of a duplicated region in the human louse p-endosymbiont at the end of the primary chromosome and a small duplicated region in the plasmid (Figure 2). These regions encode for duplicate copies of 11 genes.


Genome sequence of Candidatus Riesia pediculischaeffi, endosymbiont of chimpanzee lice, and genomic comparison of recently acquired endosymbionts from human and chimpanzee lice.

Boyd BM, Allen JM, de Crécy-Lagard V, Reed DL - G3 (Bethesda) (2014)

Alignment of the 5.2-kb plasmid from the chimpanzee louse p-endosymbiont to the 7.7-kb plasmid from the human louse p-endosymbiont that encodes genes involved pantothenate biosynthesis. Black inner ring is human louse p-endosymbiont plasmid reference sequence, red ring represents the annotation of human louse p-endosymbiont plasmid, and purple outer ring is alignment of query chimpanzee louse p-endosymbiont plasmid sequence. Genes involved in de novo synthesis of pantothenate (panB, panC, and panE) are labeled in red. Image generated using BRIG (Alikhan et al. 2011).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4232544&req=5

fig2: Alignment of the 5.2-kb plasmid from the chimpanzee louse p-endosymbiont to the 7.7-kb plasmid from the human louse p-endosymbiont that encodes genes involved pantothenate biosynthesis. Black inner ring is human louse p-endosymbiont plasmid reference sequence, red ring represents the annotation of human louse p-endosymbiont plasmid, and purple outer ring is alignment of query chimpanzee louse p-endosymbiont plasmid sequence. Genes involved in de novo synthesis of pantothenate (panB, panC, and panE) are labeled in red. Image generated using BRIG (Alikhan et al. 2011).
Mentions: This genome was similar to the human louse p-endosymbiont (Ca. Riesia pediculicola) genome in size and composition (Table 2). Overall gene order and genomic synteny have been maintained between these species, with the exception of a duplicated region in the human louse p-endosymbiont at the end of the primary chromosome and a small duplicated region in the plasmid (Figure 2). These regions encode for duplicate copies of 11 genes.

Bottom Line: Although gene loss was detected, it was not significantly greater than in older endosymbionts from aphids and ants.Movement of these genes onto a plasmid may be functionally and evolutionarily significant, potentially increasing production and guarding against the deleterious effects of mutation.Ultimately sequencing additional louse p-endosymbiont genomes will provide a model system for studying genome evolution in obligate host associated bacteria.

View Article: PubMed Central - PubMed

Affiliation: Florida Museum of Natural History, University of Florida, Gainesville, Florida 32611 Genetics and Genomics Graduate Program, University of Florida, Gainesville, Florida 32610 bboyd@ufl.edu.

Show MeSH
Related in: MedlinePlus