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Impact of a stepwise protocol for treating pain on pain intensity in nursing home patients with dementia: a cluster randomized trial.

Sandvik RK, Selbaek G, Seifert R, Aarsland D, Ballard C, Corbett A, Husebo BS - Eur J Pain (2014)

Bottom Line: The SPTP conferred significant benefit in MOBID-2 scores compared with the control group [average treatment effect (ATE) -1.388; p < 0.001] at week 8, and MOBID-2 scores worsened during the washout period (ATE = -0.701; p = 0.022).Examining different analgesic treatments, benefit was conferred to patients receiving acetaminophen compared with the controls at week 2 (ATE = -0.663; p = 0.010), continuing to increase until week 8 (ATE = -1.297; p < 0.001).Pain medication significantly improved pain in the intervention group, with indications that acetaminophen also improved ADL function.

View Article: PubMed Central - PubMed

Affiliation: Department of Global Public Health and Primary Care, Centre for Elderly- and Nursing Home Medicine, University of Bergen, Norway; Institute for Nursing Subjects, Bergen University College, Norway; Centre for Old Age Psychiatric Research, Innlandet Hospital Trust, Ottestad, Norway.

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MOBID-2 Pain Scale total score with mean and standard error of the mean by control and treatment group over study period in total study sample.
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fig02: MOBID-2 Pain Scale total score with mean and standard error of the mean by control and treatment group over study period in total study sample.

Mentions: Analysis of pain intensity outcomes showed a significant improvement in the treatment group compared to controls in weeks 2 [average treatment effect (ATE) −0.703; SE 0.24; p = 0.004] and 8 (ATE = −1.393; SE 0.3; p < 0.001) (Table 2). This improvement was seen in MOBID-2 overall pain intensity (Fig. 2) in addition to specific items assessing musculoskeletal pain (Fig. 3) and pain related to internal organs, head and skin (Fig. 4). A sub-analysis of the participants who had a score of 3 or greater on the MOBID-2 Pain Scale at baseline also showed significant benefit in the treatment group compared with control (ATE = −1.739; p < 0.001) in week 8, with an average difference in pain reduction of 50% from baseline to week 8 in the treatment group.


Impact of a stepwise protocol for treating pain on pain intensity in nursing home patients with dementia: a cluster randomized trial.

Sandvik RK, Selbaek G, Seifert R, Aarsland D, Ballard C, Corbett A, Husebo BS - Eur J Pain (2014)

MOBID-2 Pain Scale total score with mean and standard error of the mean by control and treatment group over study period in total study sample.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4232010&req=5

fig02: MOBID-2 Pain Scale total score with mean and standard error of the mean by control and treatment group over study period in total study sample.
Mentions: Analysis of pain intensity outcomes showed a significant improvement in the treatment group compared to controls in weeks 2 [average treatment effect (ATE) −0.703; SE 0.24; p = 0.004] and 8 (ATE = −1.393; SE 0.3; p < 0.001) (Table 2). This improvement was seen in MOBID-2 overall pain intensity (Fig. 2) in addition to specific items assessing musculoskeletal pain (Fig. 3) and pain related to internal organs, head and skin (Fig. 4). A sub-analysis of the participants who had a score of 3 or greater on the MOBID-2 Pain Scale at baseline also showed significant benefit in the treatment group compared with control (ATE = −1.739; p < 0.001) in week 8, with an average difference in pain reduction of 50% from baseline to week 8 in the treatment group.

Bottom Line: The SPTP conferred significant benefit in MOBID-2 scores compared with the control group [average treatment effect (ATE) -1.388; p < 0.001] at week 8, and MOBID-2 scores worsened during the washout period (ATE = -0.701; p = 0.022).Examining different analgesic treatments, benefit was conferred to patients receiving acetaminophen compared with the controls at week 2 (ATE = -0.663; p = 0.010), continuing to increase until week 8 (ATE = -1.297; p < 0.001).Pain medication significantly improved pain in the intervention group, with indications that acetaminophen also improved ADL function.

View Article: PubMed Central - PubMed

Affiliation: Department of Global Public Health and Primary Care, Centre for Elderly- and Nursing Home Medicine, University of Bergen, Norway; Institute for Nursing Subjects, Bergen University College, Norway; Centre for Old Age Psychiatric Research, Innlandet Hospital Trust, Ottestad, Norway.

Show MeSH
Related in: MedlinePlus