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Building a national direction for research in the prevention of mother to child transmission of HIV: results from a national prioritization initiative in Malawi.

Landes M, van Lettow M, Cataldo F, Chan AK, Tippett Barr B, Harries AD, Bedell R - Health Res Policy Syst (2013)

Bottom Line: In addition, two cross-cutting themes arose: partner involvement in PMTCT services and cost-effectiveness as a guide to priority setting.The results of the workshop were presented to the national technical working groups and the National AIDS Commission.This workshop contributed to defining and coordinating the national agenda for research priorities.

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Affiliation: Dignitas International, PO Box 1071 Zomba, Malawi. m.vanlettow@dignitasinternational.org.

ABSTRACT

Background: In 2011, Malawi initiated an ambitious program for the prevention of maternal to child transmission (PMTCT) of HIV, called 'Option B+,' which employs a universal test and life-long treatment strategy for all pregnant women. Priority setting should take place in defining a national research agenda for evaluating Option B + rollout in Malawi.

Methods: In April 2011, a three-day workshop took place for all major stakeholders in PMTCT aiming to provide an update on current PMTCT operational research in Malawi, find consensus on key questions not yet being addressed, identify opportunities for collaboration, and develop multi-partner research proposals.

Results: Overall, 24 participants attended the workshop including representatives from the Ministry of Health, the National AIDS Commission and 12 multilateral, non-governmental organizations and academic partners.Three interrelated clusters emerged as priorities for research: i) pregnancy intentions and family planning needs; ii) evaluation of models of care; and iii) determinants of uptake, adherence, and retention of women for Option B+. In addition, two cross-cutting themes arose: partner involvement in PMTCT services and cost-effectiveness as a guide to priority setting. Within each cluster a coordinator was designated and a proposed plan for research and potential collaborators were discussed. The results of the workshop were presented to the national technical working groups and the National AIDS Commission. Several large-scale, collaborative proposals have been developed and funded to address the research areas defined.

Conclusions: Option B + represents a significant change in PMTCT policy in Malawi and the process for evaluation of the Malawi PMTCT strategy is outlined. This workshop contributed to defining and coordinating the national agenda for research priorities.

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Option B+, prevention of mother-to-child transmission cascade.
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Figure 1: Option B+, prevention of mother-to-child transmission cascade.

Mentions: Discussion considered operational research for the entire PMTCT cascade (Figure 1), from pre-pregnancy and contraception through pregnancy and lactation to follow-up of HIV-exposed and infected infants. In particular, the workshop addressed these issues in the context of Malawi’s new policy change to Option B + .


Building a national direction for research in the prevention of mother to child transmission of HIV: results from a national prioritization initiative in Malawi.

Landes M, van Lettow M, Cataldo F, Chan AK, Tippett Barr B, Harries AD, Bedell R - Health Res Policy Syst (2013)

Option B+, prevention of mother-to-child transmission cascade.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4231351&req=5

Figure 1: Option B+, prevention of mother-to-child transmission cascade.
Mentions: Discussion considered operational research for the entire PMTCT cascade (Figure 1), from pre-pregnancy and contraception through pregnancy and lactation to follow-up of HIV-exposed and infected infants. In particular, the workshop addressed these issues in the context of Malawi’s new policy change to Option B + .

Bottom Line: In addition, two cross-cutting themes arose: partner involvement in PMTCT services and cost-effectiveness as a guide to priority setting.The results of the workshop were presented to the national technical working groups and the National AIDS Commission.This workshop contributed to defining and coordinating the national agenda for research priorities.

View Article: PubMed Central - HTML - PubMed

Affiliation: Dignitas International, PO Box 1071 Zomba, Malawi. m.vanlettow@dignitasinternational.org.

ABSTRACT

Background: In 2011, Malawi initiated an ambitious program for the prevention of maternal to child transmission (PMTCT) of HIV, called 'Option B+,' which employs a universal test and life-long treatment strategy for all pregnant women. Priority setting should take place in defining a national research agenda for evaluating Option B + rollout in Malawi.

Methods: In April 2011, a three-day workshop took place for all major stakeholders in PMTCT aiming to provide an update on current PMTCT operational research in Malawi, find consensus on key questions not yet being addressed, identify opportunities for collaboration, and develop multi-partner research proposals.

Results: Overall, 24 participants attended the workshop including representatives from the Ministry of Health, the National AIDS Commission and 12 multilateral, non-governmental organizations and academic partners.Three interrelated clusters emerged as priorities for research: i) pregnancy intentions and family planning needs; ii) evaluation of models of care; and iii) determinants of uptake, adherence, and retention of women for Option B+. In addition, two cross-cutting themes arose: partner involvement in PMTCT services and cost-effectiveness as a guide to priority setting. Within each cluster a coordinator was designated and a proposed plan for research and potential collaborators were discussed. The results of the workshop were presented to the national technical working groups and the National AIDS Commission. Several large-scale, collaborative proposals have been developed and funded to address the research areas defined.

Conclusions: Option B + represents a significant change in PMTCT policy in Malawi and the process for evaluation of the Malawi PMTCT strategy is outlined. This workshop contributed to defining and coordinating the national agenda for research priorities.

Show MeSH
Related in: MedlinePlus