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World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research.

Becker CM, Laufer MR, Stratton P, Hummelshoj L, Missmer SA, Zondervan KT, Adamson GD, WERF EPHect Working Gro - Fertil. Steril. (2014)

Bottom Line: An international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries.A postsurgical scoring sheet containing general and gynecological patient and procedural information, extent of disease, the location and type of endometriotic lesion, and any other findings was developed during several rounds of review.This is the first multicenter, international collaboration between academic centers and industry addressing standardization of phenotypic data collection for a specific disease.

View Article: PubMed Central - PubMed

Affiliation: Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom; Endometriosis CaRe Centre Oxford, University of Oxford, Oxford, United Kingdom. Electronic address: christian.becker@obs-gyn.ox.ac.uk.

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Flow diagram depicting the WERF EPHect development and consensus process (surgical data collection).
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Related In: Results  -  Collection


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fig1: Flow diagram depicting the WERF EPHect development and consensus process (surgical data collection).

Mentions: We conducted two workshops in March and July 2013, bringing together leaders in endometriosis research worldwide to develop and reach consensus on evidence-based phenome collection and SOP guidelines, followed by several rounds of expert review by the WERF EPHect Working Group (Fig. 1). During Workshop I, four areas of standardization and harmonization were defined: (I) surgical phenotyping; (II) nonsurgical clinical/epidemiologic phenotyping; (III) fluid sample; and (IV) tissue sample collection, processing, and storage protocols for molecular and genetic phenotyping. To date, the WERF EPHect global initiative has involved 34 clinical/academic centers and three industry collaborators (54 participants) from 16 countries on five continents.


World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research.

Becker CM, Laufer MR, Stratton P, Hummelshoj L, Missmer SA, Zondervan KT, Adamson GD, WERF EPHect Working Gro - Fertil. Steril. (2014)

Flow diagram depicting the WERF EPHect development and consensus process (surgical data collection).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4230690&req=5

fig1: Flow diagram depicting the WERF EPHect development and consensus process (surgical data collection).
Mentions: We conducted two workshops in March and July 2013, bringing together leaders in endometriosis research worldwide to develop and reach consensus on evidence-based phenome collection and SOP guidelines, followed by several rounds of expert review by the WERF EPHect Working Group (Fig. 1). During Workshop I, four areas of standardization and harmonization were defined: (I) surgical phenotyping; (II) nonsurgical clinical/epidemiologic phenotyping; (III) fluid sample; and (IV) tissue sample collection, processing, and storage protocols for molecular and genetic phenotyping. To date, the WERF EPHect global initiative has involved 34 clinical/academic centers and three industry collaborators (54 participants) from 16 countries on five continents.

Bottom Line: An international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries.A postsurgical scoring sheet containing general and gynecological patient and procedural information, extent of disease, the location and type of endometriotic lesion, and any other findings was developed during several rounds of review.This is the first multicenter, international collaboration between academic centers and industry addressing standardization of phenotypic data collection for a specific disease.

View Article: PubMed Central - PubMed

Affiliation: Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom; Endometriosis CaRe Centre Oxford, University of Oxford, Oxford, United Kingdom. Electronic address: christian.becker@obs-gyn.ox.ac.uk.

Show MeSH
Related in: MedlinePlus