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Cutaneous involvement as the initial presentation of metastatic breast adenocarcinoma - Case report.

Siqueira VR, Frota AS, Maia IL, Queiroz HM, Valença Júnior JT, Accioly Filho JW - An Bras Dermatol (2014 Nov-Dec)

Bottom Line: It occurs late in the course of the disease but can be a sign of an unknown neoplasm.A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported.It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease.

View Article: PubMed Central - PubMed

Affiliation: Universidade Federal do Ceará, Fortaleza, CE, Brazil.

ABSTRACT
Cutaneous metastasis is an uncommon manifestation of visceral malignancy. It occurs late in the course of the disease but can be a sign of an unknown neoplasm. A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported. It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease. Biopsies of ulcers which do not heal, persistent hardened erythema and cutaneous nodules of unknown cause must be performed, since the evidence of cutaneous metastasis can be of extreme importance for the diagnosis, staging and prognosis of an internal cancer. In this scenario, the dermatologist plays a fundamental role and should be always attentive to this diagnostic possibility.

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Related in: MedlinePlus

NMR of breasts, in T2, showing spiculated nodular lesion in the right breast.Contiguity of lesion with skin and invasion of subjacent thoracic wall isobserved
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f06: NMR of breasts, in T2, showing spiculated nodular lesion in the right breast.Contiguity of lesion with skin and invasion of subjacent thoracic wall isobserved

Mentions: Nuclear magnetic resonance (NMR) of breasts was performed, which demonstrated aspiculated nodular lesion in the right breast, medially, at the level of theintermammary cleft, measuring around 32x30 mm, determining adjacent cutaneous retractionand thickening, with signs of invasion of adjacent thoracic wall, classified as BI-RADS5 (Figure 6).


Cutaneous involvement as the initial presentation of metastatic breast adenocarcinoma - Case report.

Siqueira VR, Frota AS, Maia IL, Queiroz HM, Valença Júnior JT, Accioly Filho JW - An Bras Dermatol (2014 Nov-Dec)

NMR of breasts, in T2, showing spiculated nodular lesion in the right breast.Contiguity of lesion with skin and invasion of subjacent thoracic wall isobserved
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4230665&req=5

f06: NMR of breasts, in T2, showing spiculated nodular lesion in the right breast.Contiguity of lesion with skin and invasion of subjacent thoracic wall isobserved
Mentions: Nuclear magnetic resonance (NMR) of breasts was performed, which demonstrated aspiculated nodular lesion in the right breast, medially, at the level of theintermammary cleft, measuring around 32x30 mm, determining adjacent cutaneous retractionand thickening, with signs of invasion of adjacent thoracic wall, classified as BI-RADS5 (Figure 6).

Bottom Line: It occurs late in the course of the disease but can be a sign of an unknown neoplasm.A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported.It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease.

View Article: PubMed Central - PubMed

Affiliation: Universidade Federal do Ceará, Fortaleza, CE, Brazil.

ABSTRACT
Cutaneous metastasis is an uncommon manifestation of visceral malignancy. It occurs late in the course of the disease but can be a sign of an unknown neoplasm. A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported. It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease. Biopsies of ulcers which do not heal, persistent hardened erythema and cutaneous nodules of unknown cause must be performed, since the evidence of cutaneous metastasis can be of extreme importance for the diagnosis, staging and prognosis of an internal cancer. In this scenario, the dermatologist plays a fundamental role and should be always attentive to this diagnostic possibility.

Show MeSH
Related in: MedlinePlus