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Cutaneous involvement as the initial presentation of metastatic breast adenocarcinoma - Case report.

Siqueira VR, Frota AS, Maia IL, Queiroz HM, Valença Júnior JT, Accioly Filho JW - An Bras Dermatol (2014 Nov-Dec)

Bottom Line: It occurs late in the course of the disease but can be a sign of an unknown neoplasm.A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported.It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease.

View Article: PubMed Central - PubMed

Affiliation: Universidade Federal do Ceará, Fortaleza, CE, Brazil.

ABSTRACT
Cutaneous metastasis is an uncommon manifestation of visceral malignancy. It occurs late in the course of the disease but can be a sign of an unknown neoplasm. A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported. It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease. Biopsies of ulcers which do not heal, persistent hardened erythema and cutaneous nodules of unknown cause must be performed, since the evidence of cutaneous metastasis can be of extreme importance for the diagnosis, staging and prognosis of an internal cancer. In this scenario, the dermatologist plays a fundamental role and should be always attentive to this diagnostic possibility.

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Related in: MedlinePlus

Detail of intermammary lesion evidencing erythema, infiltration and irregularsurface
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f02: Detail of intermammary lesion evidencing erythema, infiltration and irregularsurface

Mentions: Female patient, 68 years old, with onset of asymptomatic lesion in the intermammaryregion for about six months. She denied other complaints. At the physical examinationshe presented an erythematous infiltrated plaque of irregular surface, with centralretraction, of hardened consistency, adhered to deep planes in the intermammary region(Figures 1 and 2). No other changes were shown in the rest of the physical examination.


Cutaneous involvement as the initial presentation of metastatic breast adenocarcinoma - Case report.

Siqueira VR, Frota AS, Maia IL, Queiroz HM, Valença Júnior JT, Accioly Filho JW - An Bras Dermatol (2014 Nov-Dec)

Detail of intermammary lesion evidencing erythema, infiltration and irregularsurface
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4230665&req=5

f02: Detail of intermammary lesion evidencing erythema, infiltration and irregularsurface
Mentions: Female patient, 68 years old, with onset of asymptomatic lesion in the intermammaryregion for about six months. She denied other complaints. At the physical examinationshe presented an erythematous infiltrated plaque of irregular surface, with centralretraction, of hardened consistency, adhered to deep planes in the intermammary region(Figures 1 and 2). No other changes were shown in the rest of the physical examination.

Bottom Line: It occurs late in the course of the disease but can be a sign of an unknown neoplasm.A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported.It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease.

View Article: PubMed Central - PubMed

Affiliation: Universidade Federal do Ceará, Fortaleza, CE, Brazil.

ABSTRACT
Cutaneous metastasis is an uncommon manifestation of visceral malignancy. It occurs late in the course of the disease but can be a sign of an unknown neoplasm. A case of local cutaneous metastasis by contiguity with breast adenocarcinoma is reported. It presented as initial manifestation and main complaint of a 68-year-old woman, with no family history and negative screening tests for the disease. Biopsies of ulcers which do not heal, persistent hardened erythema and cutaneous nodules of unknown cause must be performed, since the evidence of cutaneous metastasis can be of extreme importance for the diagnosis, staging and prognosis of an internal cancer. In this scenario, the dermatologist plays a fundamental role and should be always attentive to this diagnostic possibility.

Show MeSH
Related in: MedlinePlus