A. Papulonecrotic tuberculid – erythematous papules w

Update on cutaneous tuberculosis. Dias MF, Bernardes Filho F, Quaresma MV, Nascimento LV, Nery JA, Azulay DR - An Bras Dermatol (2014 Nov-Dec) Bottom Line: Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin.Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects.Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic. View Article: PubMed Central - PubMed Affiliation: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro (IDPRDA-SCMRJ), Rio de Janeiro, RJ, Brazil. ABSTRACT Tuberculosis continues to draw special attention from health care professionals and society in general. Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin. Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects. Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic. This paper aims to review the current situation of cutaneous tuberculosis in light of this new scenario, highlighting the emergence of new and more specific methods of diagnosis, and the molecular and cellular mechanisms that regulate the parasite-host interaction. Show MeSH Major Tuberculosis, Cutaneous/drug therapy/etiology/pathology Minor AIDS-Related Opportunistic Infections/pathology Antitubercular Agents/therapeutic use Female Humans Male Mycobacterium tuberculosis Tuberculin Test Related in: MedlinePlus	© Copyright Policy - open-access Related In: Results - Collection License Show All Figures getmorefigures.php?uid=PMC4230662&req=5 f03: A. Papulonecrotic tuberculid – erythematous papules with centralcrust; B and C: Erythema induratum of Bazin Mentions: A. Scrofuloderma (Courtesy from Dr. Vitor Paulo Perez - Fiocruz);B. Chest X-ray in posterioranterior (PA) position showing a rightinfraclavicular opacity (red arrow), images of thick-walled cavities, acinarlesions permeating the left superior lobe (blue arrow) and pleural effusion on theleft (yellow arrow). Pulmonary tuberculosis – Chest X-ray from the same patient onFigure 3 (Courtesy fsrom Dr. Vitor PauloPerez - Fiocruz); C. Scrofuloderma (Courtesy from Dra. Julia OcampoLyra da Silva – Bonsucesso Federal Hospital); D. Scrofuloderma.Ulcerated nodular lesion on the left inguinal region of an HIV positivepatient

Update on cutaneous tuberculosis.

Dias MF, Bernardes Filho F, Quaresma MV, Nascimento LV, Nery JA, Azulay DR - An Bras Dermatol (2014 Nov-Dec)

Bottom Line: Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin.Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects.Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic.

View Article: PubMed Central - PubMed

Affiliation: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro (IDPRDA-SCMRJ), Rio de Janeiro, RJ, Brazil.

ABSTRACT

Tuberculosis continues to draw special attention from health care professionals and society in general. Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin. Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects. Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic. This paper aims to review the current situation of cutaneous tuberculosis in light of this new scenario, highlighting the emergence of new and more specific methods of diagnosis, and the molecular and cellular mechanisms that regulate the parasite-host interaction.

Show MeSH

Related in: MedlinePlus

A. Papulonecrotic tuberculid – erythematous papules with centralcrust; B and C: Erythema induratum of Bazin

Related In: Results - Collection

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f03: A. Papulonecrotic tuberculid – erythematous papules with centralcrust; B and C: Erythema induratum of Bazin

Mentions: A. Scrofuloderma (Courtesy from Dr. Vitor Paulo Perez - Fiocruz);B. Chest X-ray in posterioranterior (PA) position showing a rightinfraclavicular opacity (red arrow), images of thick-walled cavities, acinarlesions permeating the left superior lobe (blue arrow) and pleural effusion on theleft (yellow arrow). Pulmonary tuberculosis – Chest X-ray from the same patient onFigure 3 (Courtesy fsrom Dr. Vitor PauloPerez - Fiocruz); C. Scrofuloderma (Courtesy from Dra. Julia OcampoLyra da Silva – Bonsucesso Federal Hospital); D. Scrofuloderma.Ulcerated nodular lesion on the left inguinal region of an HIV positivepatient