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Update on cutaneous tuberculosis.

Dias MF, Bernardes Filho F, Quaresma MV, Nascimento LV, Nery JA, Azulay DR - An Bras Dermatol (2014 Nov-Dec)

Bottom Line: Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin.Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects.Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic.

View Article: PubMed Central - PubMed

Affiliation: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro (IDPRDA-SCMRJ), Rio de Janeiro, RJ, Brazil.

ABSTRACT
Tuberculosis continues to draw special attention from health care professionals and society in general. Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin. Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects. Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic. This paper aims to review the current situation of cutaneous tuberculosis in light of this new scenario, highlighting the emergence of new and more specific methods of diagnosis, and the molecular and cellular mechanisms that regulate the parasite-host interaction.

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Related in: MedlinePlus

A. Scrofuloderma (Courtesy from Dr. Vitor Paulo Perez - Fiocruz);B. Chest X-ray in posterioranterior (PA) position showing a rightinfraclavicular opacity (red arrow), images of thick-walled cavities, acinarlesions permeating the left superior lobe (blue arrow) and pleural effusion on theleft (yellow arrow). Pulmonary tuberculosis – Chest X-ray from the same patient onFigure 3 (Courtesy fsrom Dr. Vitor PauloPerez - Fiocruz); C. Scrofuloderma (Courtesy from Dra. Julia OcampoLyra da Silva – Bonsucesso Federal Hospital); D. Scrofuloderma.Ulcerated nodular lesion on the left inguinal region of an HIV positivepatient
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f02: A. Scrofuloderma (Courtesy from Dr. Vitor Paulo Perez - Fiocruz);B. Chest X-ray in posterioranterior (PA) position showing a rightinfraclavicular opacity (red arrow), images of thick-walled cavities, acinarlesions permeating the left superior lobe (blue arrow) and pleural effusion on theleft (yellow arrow). Pulmonary tuberculosis – Chest X-ray from the same patient onFigure 3 (Courtesy fsrom Dr. Vitor PauloPerez - Fiocruz); C. Scrofuloderma (Courtesy from Dra. Julia OcampoLyra da Silva – Bonsucesso Federal Hospital); D. Scrofuloderma.Ulcerated nodular lesion on the left inguinal region of an HIV positivepatient

Mentions: It is the most common form in our midst, occurring in children and young people. Theinfection route is always endogenous, usually secondary to bone or lymph node TB.Clinical lesions appear as nodules, gumma and ulcerations due to fistulae. There arereports of involvement of cervical and inguinocrural regions, as well as lesions inepididymis, conjunctiva and mouth. Patients may have active pulmonary or pleural diseasewith systemic symptoms (Figure 2).2,5,73,74,75


Update on cutaneous tuberculosis.

Dias MF, Bernardes Filho F, Quaresma MV, Nascimento LV, Nery JA, Azulay DR - An Bras Dermatol (2014 Nov-Dec)

A. Scrofuloderma (Courtesy from Dr. Vitor Paulo Perez - Fiocruz);B. Chest X-ray in posterioranterior (PA) position showing a rightinfraclavicular opacity (red arrow), images of thick-walled cavities, acinarlesions permeating the left superior lobe (blue arrow) and pleural effusion on theleft (yellow arrow). Pulmonary tuberculosis – Chest X-ray from the same patient onFigure 3 (Courtesy fsrom Dr. Vitor PauloPerez - Fiocruz); C. Scrofuloderma (Courtesy from Dra. Julia OcampoLyra da Silva – Bonsucesso Federal Hospital); D. Scrofuloderma.Ulcerated nodular lesion on the left inguinal region of an HIV positivepatient
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4230662&req=5

f02: A. Scrofuloderma (Courtesy from Dr. Vitor Paulo Perez - Fiocruz);B. Chest X-ray in posterioranterior (PA) position showing a rightinfraclavicular opacity (red arrow), images of thick-walled cavities, acinarlesions permeating the left superior lobe (blue arrow) and pleural effusion on theleft (yellow arrow). Pulmonary tuberculosis – Chest X-ray from the same patient onFigure 3 (Courtesy fsrom Dr. Vitor PauloPerez - Fiocruz); C. Scrofuloderma (Courtesy from Dra. Julia OcampoLyra da Silva – Bonsucesso Federal Hospital); D. Scrofuloderma.Ulcerated nodular lesion on the left inguinal region of an HIV positivepatient
Mentions: It is the most common form in our midst, occurring in children and young people. Theinfection route is always endogenous, usually secondary to bone or lymph node TB.Clinical lesions appear as nodules, gumma and ulcerations due to fistulae. There arereports of involvement of cervical and inguinocrural regions, as well as lesions inepididymis, conjunctiva and mouth. Patients may have active pulmonary or pleural diseasewith systemic symptoms (Figure 2).2,5,73,74,75

Bottom Line: Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin.Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects.Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic.

View Article: PubMed Central - PubMed

Affiliation: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro (IDPRDA-SCMRJ), Rio de Janeiro, RJ, Brazil.

ABSTRACT
Tuberculosis continues to draw special attention from health care professionals and society in general. Cutaneous tuberculosis is an infection caused by M. tuberculosis complex, M. bovis and bacillus Calmette-Guérin. Depending on individual immunity, environmental factors and the type of inoculum, it may present varied clinical and evolutionary aspects. Patients with HIV and those using immunobiological drugs are more prone to infection, which is a great concern in centers where the disease is considered endemic. This paper aims to review the current situation of cutaneous tuberculosis in light of this new scenario, highlighting the emergence of new and more specific methods of diagnosis, and the molecular and cellular mechanisms that regulate the parasite-host interaction.

Show MeSH
Related in: MedlinePlus