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Lower facial remodeling with botulinum toxin type A for the treatment of masseter hypertrophy.

Klein FH, Brenner FM, Sato MS, Robert FM, Helmer KA - An Bras Dermatol (2014 Nov-Dec)

Bottom Line: Observed adverse effects were masticatory fatigue, smile limitation, and smile asymmetry.Smile limitation had a higher incidence compared to that reported in the literature and may result from risorius muscle blockage caused by toxin dissemination.Despite its side effects, 80% of the patients would like to repeat the treatment.

View Article: PubMed Central - PubMed

Affiliation: Private practice particular - Criciúma (SC), Brazil, Criciúma, SC, Brazil.

ABSTRACT

Background: Masseter hypertrophy has been treated with botulinum toxin injections because of esthetic complaints especially in Asians.

Objectives: The goal of the present study was to evaluate the efficacy of abobotulin toxin use in masseter hipertrophy treatment in Brazilians.

Methods: Ten Brazilian female patients with masseter hypertrophy were subjected to injections of 90U of abobotulinum toxin A applied on each side respecting the safety zone stabilished in literature and were followed up for 24 weeks.

Results: When analyzing the coefficients between measures of middle and lower third of the face obtained from standardized photographs, an increase was observed, with statistical significance at 2 weeks (p=0.005) and 12 weeks (p=0.001). The progression of lower third reduction was 3.94%, 5.26%, 11.99%, and 5.47% (2, 4, 12, and 24 weeks respectively). All patients showed improvement in bruxism after treatment. Observed adverse effects were masticatory fatigue, smile limitation, and smile asymmetry.

Conclusion: The use of abobotulinum toxin A for masseter hypertrophy is effective in Brazilians and reached its maximum effect of facial thinning at 12 weeks. Smile limitation had a higher incidence compared to that reported in the literature and may result from risorius muscle blockage caused by toxin dissemination. Despite its side effects, 80% of the patients would like to repeat the treatment.

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Related in: MedlinePlus

Smile asymmetry associated with smile limitation in 2 patients
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f05: Smile asymmetry associated with smile limitation in 2 patients


Lower facial remodeling with botulinum toxin type A for the treatment of masseter hypertrophy.

Klein FH, Brenner FM, Sato MS, Robert FM, Helmer KA - An Bras Dermatol (2014 Nov-Dec)

Smile asymmetry associated with smile limitation in 2 patients
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4230655&req=5

f05: Smile asymmetry associated with smile limitation in 2 patients
Bottom Line: Observed adverse effects were masticatory fatigue, smile limitation, and smile asymmetry.Smile limitation had a higher incidence compared to that reported in the literature and may result from risorius muscle blockage caused by toxin dissemination.Despite its side effects, 80% of the patients would like to repeat the treatment.

View Article: PubMed Central - PubMed

Affiliation: Private practice particular - Criciúma (SC), Brazil, Criciúma, SC, Brazil.

ABSTRACT

Background: Masseter hypertrophy has been treated with botulinum toxin injections because of esthetic complaints especially in Asians.

Objectives: The goal of the present study was to evaluate the efficacy of abobotulin toxin use in masseter hipertrophy treatment in Brazilians.

Methods: Ten Brazilian female patients with masseter hypertrophy were subjected to injections of 90U of abobotulinum toxin A applied on each side respecting the safety zone stabilished in literature and were followed up for 24 weeks.

Results: When analyzing the coefficients between measures of middle and lower third of the face obtained from standardized photographs, an increase was observed, with statistical significance at 2 weeks (p=0.005) and 12 weeks (p=0.001). The progression of lower third reduction was 3.94%, 5.26%, 11.99%, and 5.47% (2, 4, 12, and 24 weeks respectively). All patients showed improvement in bruxism after treatment. Observed adverse effects were masticatory fatigue, smile limitation, and smile asymmetry.

Conclusion: The use of abobotulinum toxin A for masseter hypertrophy is effective in Brazilians and reached its maximum effect of facial thinning at 12 weeks. Smile limitation had a higher incidence compared to that reported in the literature and may result from risorius muscle blockage caused by toxin dissemination. Despite its side effects, 80% of the patients would like to repeat the treatment.

Show MeSH
Related in: MedlinePlus