Limits...
The role of elastosonography, gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules.

Tatar IG, Kurt A, Yilmaz KB, Doğan M, Hekimoglu B, Hucumenoglu S - Radiol Oncol (2014)

Bottom Line: Most of the benign nodules had score 2 and 3, none of them displayed score 5.On the other hand, none of the malignant nodules had score 1 and 2, most of them displaying score 5.A change in the diagnostic algorithm of the thyroid nodules should be considered integrating the elastosonographic analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Ankara Diskapı Training and Research Hospital, Ankara, Turkey.

ABSTRACT

Background: Ultrasound is as a noninvasive method commonly used in the work-up of thyroid nodules. This study aimed to evaluate the usefulness of sonographic and elastosonographic parameters in the discrimination of malignancy.

Patients and methods: 150 thyroid nodules were evaluated by gray-scale, Doppler and elastosonography. The cytological analysis revealed that 141 nodules were benign and 9 were malignant.

Results: Orientation of the nodule was the only sonographic parameter associated with malignancy (p = 0.003). In the strain ratio analysis the best cut-off point was 1.935 to discriminate malignancy (p = 0.000), with 100% sensitivity, 76% specificity, 100% negative predictive value, 78.5% positive predictive value and 78% accuracy rate. There was a statistically significant correlation between the elasticity score and malignancy (p = 0.001). Most of the benign nodules had score 2 and 3, none of them displayed score 5. On the other hand, none of the malignant nodules had score 1 and 2, most of them displaying score 5.

Conclusions: A change in the diagnostic algorithm of the thyroid nodules should be considered integrating the elastosonographic analysis.

No MeSH data available.


Related in: MedlinePlus

ROC curve analysis of the strain ratio measurements of thyroid nodules by elastosonography.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC4230554&req=5

f2-rado-48-04-348: ROC curve analysis of the strain ratio measurements of thyroid nodules by elastosonography.

Mentions: SR is calculated by dividing the mean strain of the adjacent normal thyroid parenchymal tissue by the mean intranodular strain. By using the receiver operating characteristic analysis, the best cut-off point was found to be 1.935 to differentiate benign from malignant nodules with 95% confidence interval (p = 0.000, AUC = 0.920) (Figure 2). The sensitivity, specificity, negative predictive value, positive predictive value and accuracy rate of the SR analysis were 100%, 76%, 100%, 78.5% and 78% respectively.


The role of elastosonography, gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules.

Tatar IG, Kurt A, Yilmaz KB, Doğan M, Hekimoglu B, Hucumenoglu S - Radiol Oncol (2014)

ROC curve analysis of the strain ratio measurements of thyroid nodules by elastosonography.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4230554&req=5

f2-rado-48-04-348: ROC curve analysis of the strain ratio measurements of thyroid nodules by elastosonography.
Mentions: SR is calculated by dividing the mean strain of the adjacent normal thyroid parenchymal tissue by the mean intranodular strain. By using the receiver operating characteristic analysis, the best cut-off point was found to be 1.935 to differentiate benign from malignant nodules with 95% confidence interval (p = 0.000, AUC = 0.920) (Figure 2). The sensitivity, specificity, negative predictive value, positive predictive value and accuracy rate of the SR analysis were 100%, 76%, 100%, 78.5% and 78% respectively.

Bottom Line: Most of the benign nodules had score 2 and 3, none of them displayed score 5.On the other hand, none of the malignant nodules had score 1 and 2, most of them displaying score 5.A change in the diagnostic algorithm of the thyroid nodules should be considered integrating the elastosonographic analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Ankara Diskapı Training and Research Hospital, Ankara, Turkey.

ABSTRACT

Background: Ultrasound is as a noninvasive method commonly used in the work-up of thyroid nodules. This study aimed to evaluate the usefulness of sonographic and elastosonographic parameters in the discrimination of malignancy.

Patients and methods: 150 thyroid nodules were evaluated by gray-scale, Doppler and elastosonography. The cytological analysis revealed that 141 nodules were benign and 9 were malignant.

Results: Orientation of the nodule was the only sonographic parameter associated with malignancy (p = 0.003). In the strain ratio analysis the best cut-off point was 1.935 to discriminate malignancy (p = 0.000), with 100% sensitivity, 76% specificity, 100% negative predictive value, 78.5% positive predictive value and 78% accuracy rate. There was a statistically significant correlation between the elasticity score and malignancy (p = 0.001). Most of the benign nodules had score 2 and 3, none of them displayed score 5. On the other hand, none of the malignant nodules had score 1 and 2, most of them displaying score 5.

Conclusions: A change in the diagnostic algorithm of the thyroid nodules should be considered integrating the elastosonographic analysis.

No MeSH data available.


Related in: MedlinePlus