Limits...
The Israeli National Committee for sex selection by pre-implantation genetic diagnosis: a novel approach (2005-2011).

Pessach N, Glasser S, Soskolne V, Barash A, Lerner-Geva L - Isr J Health Policy Res (2014)

Bottom Line: Most requested males, and the primary reason was the parents' intense emotional desire.Only one-fifth of the decisions were approvals, possibly reflecting reluctance to encourage non-medically-indicated PGD, a viewpoint not unique to Israel.Limitations include the relatively small number of cases and lack of access to Committee deliberation protocols.

View Article: PubMed Central - PubMed

Affiliation: The National Social Work Service, Ministry of Health, 15 Noah Mozes St, Tel-Aviv, 67442 Israel.

ABSTRACT

Background: Pre-implantation genetic diagnosis (PGD) for fetal sex selection raises complex dilemmas. In Israel, PGD is regulated by the Ministry of Health. It is basically prohibited, but exceptions can be made upon approval by the National Committee for Sex Selection by PGD for Non-Medical Reasons (the "Committee"). This report describes the Committee's work since its inception in May, 2005 through December, 2011.

Methods: Files were abstracted onto a structured form. Discrete variables were analyzed by chi-square analysis, and continuous variables by T-Test.

Results: During the study period 411 applications were received. Two-thirds of the applicants (n = 276; 67.2%) were Jewish and 26.8% were Moslem Arab. Over two-thirds (n = 285; 69.3%) had no children of the requested sex and ≥4 children of the opposite sex. Three-quarters of the requests were for a male (n = 308; 74.9%): 100% of Arab and 63% of Jewish applicants. Many noted more than one reason for their request. The most frequent category (n = 201; 48.9%) was a strong emotional desire, followed by medically-related reasons (n = 83; 20.2%). For 216 applications a decision was arrived at, with 46 (21.3%) approved. Of the remaining 195 for 192 over a year had passed since last contact with the Committee. The likelihood of approval was higher if applicants met the criterion of ≥4 same-sex children than if they didn't (33.7% vs. 11.6%, P = 0.001). The largest number of approvals were those requested for 'emotional' reasons, while the highest approval rate was for religious reasons.

Conclusions: This study reviewed the first seven years of Committee activity. Most requested males, and the primary reason was the parents' intense emotional desire. Only one-fifth of the decisions were approvals, possibly reflecting reluctance to encourage non-medically-indicated PGD, a viewpoint not unique to Israel. Limitations include the relatively small number of cases and lack of access to Committee deliberation protocols. It is recommended that longitudinal studies be conducted to gain insight into the consequences to individuals, couples and families--both those whose requests were approved and those denied-- of this major step in reproductive technologies and in society's effort to respond to them.

No MeSH data available.


Related in: MedlinePlus

Committee decisions by year of application (N = 216).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC4230365&req=5

Fig3: Committee decisions by year of application (N = 216).

Mentions: The rate of approval rose over the years, from 13.1% in 2005 to 41.4.% in 2011 (Figure 3). Of the 216 applications for which Committee decisions were made, 46 (21.3%) were approved, and 170 (78.7%) were denied. The likelihood of approval was significantly higher if the applicants met the criterion of four or more same-sex children than if not (33.7% vs. 11.6%, P = 0.001). The rate of approvals to Arab couples was somewhat higher than that to Jewish couples (28.8% vs. 18.5%) although this trend did not reach statistical significance. Regarding the eleven couples who had one or two sons and requested a son, only one of these was approved, and the others were rejected.Figure 3


The Israeli National Committee for sex selection by pre-implantation genetic diagnosis: a novel approach (2005-2011).

Pessach N, Glasser S, Soskolne V, Barash A, Lerner-Geva L - Isr J Health Policy Res (2014)

Committee decisions by year of application (N = 216).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4230365&req=5

Fig3: Committee decisions by year of application (N = 216).
Mentions: The rate of approval rose over the years, from 13.1% in 2005 to 41.4.% in 2011 (Figure 3). Of the 216 applications for which Committee decisions were made, 46 (21.3%) were approved, and 170 (78.7%) were denied. The likelihood of approval was significantly higher if the applicants met the criterion of four or more same-sex children than if not (33.7% vs. 11.6%, P = 0.001). The rate of approvals to Arab couples was somewhat higher than that to Jewish couples (28.8% vs. 18.5%) although this trend did not reach statistical significance. Regarding the eleven couples who had one or two sons and requested a son, only one of these was approved, and the others were rejected.Figure 3

Bottom Line: Most requested males, and the primary reason was the parents' intense emotional desire.Only one-fifth of the decisions were approvals, possibly reflecting reluctance to encourage non-medically-indicated PGD, a viewpoint not unique to Israel.Limitations include the relatively small number of cases and lack of access to Committee deliberation protocols.

View Article: PubMed Central - PubMed

Affiliation: The National Social Work Service, Ministry of Health, 15 Noah Mozes St, Tel-Aviv, 67442 Israel.

ABSTRACT

Background: Pre-implantation genetic diagnosis (PGD) for fetal sex selection raises complex dilemmas. In Israel, PGD is regulated by the Ministry of Health. It is basically prohibited, but exceptions can be made upon approval by the National Committee for Sex Selection by PGD for Non-Medical Reasons (the "Committee"). This report describes the Committee's work since its inception in May, 2005 through December, 2011.

Methods: Files were abstracted onto a structured form. Discrete variables were analyzed by chi-square analysis, and continuous variables by T-Test.

Results: During the study period 411 applications were received. Two-thirds of the applicants (n = 276; 67.2%) were Jewish and 26.8% were Moslem Arab. Over two-thirds (n = 285; 69.3%) had no children of the requested sex and ≥4 children of the opposite sex. Three-quarters of the requests were for a male (n = 308; 74.9%): 100% of Arab and 63% of Jewish applicants. Many noted more than one reason for their request. The most frequent category (n = 201; 48.9%) was a strong emotional desire, followed by medically-related reasons (n = 83; 20.2%). For 216 applications a decision was arrived at, with 46 (21.3%) approved. Of the remaining 195 for 192 over a year had passed since last contact with the Committee. The likelihood of approval was higher if applicants met the criterion of ≥4 same-sex children than if they didn't (33.7% vs. 11.6%, P = 0.001). The largest number of approvals were those requested for 'emotional' reasons, while the highest approval rate was for religious reasons.

Conclusions: This study reviewed the first seven years of Committee activity. Most requested males, and the primary reason was the parents' intense emotional desire. Only one-fifth of the decisions were approvals, possibly reflecting reluctance to encourage non-medically-indicated PGD, a viewpoint not unique to Israel. Limitations include the relatively small number of cases and lack of access to Committee deliberation protocols. It is recommended that longitudinal studies be conducted to gain insight into the consequences to individuals, couples and families--both those whose requests were approved and those denied-- of this major step in reproductive technologies and in society's effort to respond to them.

No MeSH data available.


Related in: MedlinePlus